Richard J. H. Wojcikiewicz

Calcium-dependent Clustering of Inositol 1,4,5-Trisphosphate Receptors

Wilson, Bridget S., Pfeiffer, Janet R., Smith, Alexander J., Oliver, Janet M., Oberdorf, Jon A., Wojcikiewicz, Richard J.H.

Rat basophilic leukemia (RBL-2H3) cells predominantly express the type II receptor for inositol 1,4,5-trisphosphate (InsP3), which operates as an InsP3-gated calcium channel. In these cells,...

Calcium-dependent Clustering of Inositol 1,4,5-Trisphosphate Receptors

Wilson, Bridget S., Pfeiffer, Janet R., Smith, Alexander J., Oliver, Janet M., Oberdorf, Jon A., Wojcikiewicz, Richard J.H.

Rat basophilic leukemia (RBL-2H3) cells predominantly express the type II receptor for inositol 1,4,5-trisphosphate (InsP3), which operates as an InsP3-gated calcium channel. In these cells,...

Reaction Diffusion Modeling of Calcium Dynamics with Realistic ER Geometry

Means, Shawn, Smith, Alexander J., Shepherd, Jason, Shadid, John, Fowler, John, Wojcikiewicz, Richard J. H., ...

We describe a finite-element model of mast cell calcium dynamics that incorporates the endoplasmic reticulum's complex geometry. The model is built upon a three-dimensional reconstruction of the...