Cloning and expression of the rabbit prostaglandin EP2 receptor (2002)
Guan, Youfei, Stillman, Brett A, Zhang, Yahua, Schneider, André, Saito, Osamu, Davis, Linda S, ...
Abstract Background Prostaglandin E 2 (PGE 2 ) has multiple physiologic roles mediated by G protein coupled receptors designated E-prostanoid, or "EP" receptors. Evidence supports an important role...
The variable region of mouse [lambda]3 chains /--by Richard M. Breyer. (1982)
Supervised by Herman Eisen.
Cloning and expression of the rabbit prostaglandin EP2 receptor
Guan, Youfei, Stillman, Brett A, Zhang, Yahua, Schneider, André, Saito, Osamu, Davis, Linda S, ...
Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II
Qi, Zhonghua, Hao, Chuan-Ming, Langenbach, Robert I., Breyer, Richard M., Redha, Reyadh, Morrow, Jason D., ...
Therapeutic use of cyclooxygenase-inhibiting (COX-inhibiting) nonsteroidal antiinflammatory drugs (NSAIDs) is often complicated by renal side effects including hypertension and edema. The present...
Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II
Zhonghua, Qi, Hao, Chuan-Ming, Langenbach, Robert I., Breyer, Richard M., Redha, Reyadh, Morrow, Jason D., ...
Yang, Li, Yamagata, Noboru, Yadav, Rajwardhan, Brandon, Suzanne, Courtney, Regina L., Morrow, Jason D., ...
Prostaglandin E2 (PGE2), a major COX metabolite, plays important roles in several facets of tumor biology. We characterized the contribution of the PGE2 EP2 receptor to cancer-associated immune...
Guan, You-Fei, Zhang, Ya-Hua, Breyer, Richard M, Davis, Linda, Breyer, Matthew D
The present study examined the expression and role of the thiazolidinedione (TZD)-activated transcription factor, peroxisome proliferator-activated receptor γ (PPARγ), in human bladder cancers. In...
Cloning and expression of the rabbit prostaglandin EP2 receptor
Guan, Youfei, Stillman, Brett A, Zhang, Yahua, Schneider, André, Saito, Osamu, Davis, Linda S, ...
Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II
Qi, Zhonghua, Hao, Chuan-Ming, Langenbach, Robert I., Breyer, Richard M., Redha, Reyadh, Morrow, Jason D., ...
Therapeutic use of cyclooxygenase-inhibiting (COX-inhibiting) nonsteroidal antiinflammatory drugs (NSAIDs) is often complicated by renal side effects including hypertension and edema. The present...
Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II
Zhonghua, Qi, Hao, Chuan-Ming, Langenbach, Robert I., Breyer, Richard M., Redha, Reyadh, Morrow, Jason D., ...
Yang, Li, Yamagata, Noboru, Yadav, Rajwardhan, Brandon, Suzanne, Courtney, Regina L., Morrow, Jason D., ...
Prostaglandin E2 (PGE2), a major COX metabolite, plays important roles in several facets of tumor biology. We characterized the contribution of the PGE2 EP2 receptor to cancer-associated immune...
Guan, You-Fei, Zhang, Ya-Hua, Breyer, Richard M, Davis, Linda, Breyer, Matthew D
The present study examined the expression and role of the thiazolidinedione (TZD)-activated transcription factor, peroxisome proliferator-activated receptor γ (PPARγ), in human bladder cancers. In...
Shie, Feng-Shiun, Breyer, Richard M., Montine, Thomas J.
Experimental therapies for Alzheimer’s disease (AD) are focused on enhanced clearance of neurotoxic Aβ peptides from brain. Microglia can be neuroprotective by phagocytosing Aβ; however, this...
Antihypertensive effects of selective prostaglandin E2 receptor subtype 1 targeting
Guan, Youfei, Zhang, Yahua, Wu, Jing, Qi, Zhonghua, Yang, Guangrui, Dou, Dou, ...
Clinical use of prostaglandin synthase–inhibiting NSAIDs is associated with the development of hypertension; however, the cardiovascular effects of antagonists for individual prostaglandin...
Mouse EP3 α, β, and γ Receptor Variants Reduce Tumor Cell Proliferation and Tumorigenesis in Vivo*
Macias-Perez, Ines M., Zent, Roy, Carmosino, Monica, Breyer, Matthew D., Breyer, Richard M., Pozzi, Ambra
Prostaglandin E2, which exerts its functions by binding to four G protein-coupled receptors (EP1-4), is implicated in tumorigenesis. Among the four E-prostanoid (EP) receptors, EP3 is unique in that...
Increased dietary NaCl induces renal medullary PGE2 production and natriuresis via the EP2 receptor
Chen, Jian, Zhao, Min, He, Wenjuan, Milne, Ginger L., Howard, Jocelyn R. H., Morrow, Jason, ...
A high-NaCl diet induces renal medullary cyclooxygenase (COX)2 expression, and selective intramedullary infusion of a COX2 inhibitor increases blood pressure in rats on a high-salt diet. The present...