Rine Dudoit

Received ***, revised ***, accepted *** Published online *** (2009)

Rine Dudoit, Houston N. Gilbert

Summary This article proposes resampling-based empirical Bayes multiple testing procedures for controlling a broad class of Type I error rates, defined as generalized tail probability (gTP) error...

DATA and PREPROCESSING (2009)

Houston N. Gilbert, Katherine S. Pollard, Rine Dudoit

Large scale biological studies often involve testing multiple hypotheses simultaneously. Our research has included resampling-based multiple testing procedures (MTPs) based on a test statistics joint...

Multiple tests of association with biological annotation metadata (2009)

Rine Dudoit

Abstract: We propose a general and formal statistical framework for multiple tests of association between known fixed features of a genome and unknown parameters of the distribution of variable...

Smoking History_____________________________ (2009)

Joint Work S, Ra Sinisi, Annette Molinaro, Rine Dudoit, Merrill Birkner, ...

ESTIMATION PROBLEMS 1. Prediction of clinical outcomes based on epidemiological and genomic data such as gene expression / single nucleotide polymorphism (SNP) / comparative genomic hybridization...

Analysis (A. Poustka) DKFZ Heidelberg Acknowledgements (2008)

Wolfgang Huber, Anja Von Heydebreck, Günther Sawitzki, Holger Sültmann, Klaus Steiner, Markus Vogt, ...

First analysis steps o quality control and optimization o calibration and error modeling o data transformations

Address for correspondence: (2007)

Rine Dudoit, Terence P. Speed, Yongchao Ge, Yongchao Ge

The burgeoning field of genomics has revived interest in multiple testing procedures by raising new methodological and computational challenges. For example, microarray experiments generate large...

Address for correspondence: (2007)

Jane Fridly, Rine Dudoit, Sandrine Dudoit

Applications of resampling methods to estimate the number of clusters and to improve the accuracy of a clustering method

Survival ensembles (2006)

Torsten Hothorn, Peter Bühlmann, Rine Dudoit, Annette Molinaro

This document reproduces the data analyses presented in Hothorn et al. (2006). For a description of the theory behind applications shown here we refer to the original manuscript. 1.1 Acute myeloid...

Supervised detection of regulatory motifs in DNA sequences (2003)

Sunduz Keles, Rine Dudoit, Rine Dudoit, Biao Xing, Biao Xing, ...

Copyright c○2003 by the authors. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic,...

ARTICLE IN PRESS (2003)

Annette M. Molinaro, Rine Dudoit

Tree-based multivariate regression and density

Supervised detection of regulatory motifs in DNA sequences (2003)

Rine Dudoit, Biao Xing, Michael B. Eisen

Identification of transcription factor binding sites (regulatory motifs) is a major interest in contemporary biology. We propose a new likelihood based method, COMODE, for identifying structural...

CROSS-VALIDATED DELE- TION/SUBSTITUTION/ADDITION ALGORITHM FOR PREDICTION: APPLICATIONS IN GENOMICS (2003)

Joint Work S, Rine Dudoit, Ra Sinisi, Annette Molinaro, Mike Eisen

1. Prediction of clinical outcomes based on epidemiological and genomic data such as gene expression / single nucleotide polymorphism (SNP) / comparative genomic hybridization (CGH). 2. Prediction of...

Asymptotic optimality of likelihoodbased cross validation (2003)

Rine Dudoit

Likelihood-based cross-validation is a statistical tool for selecting a density estimate based on n i.i.d. observations from the true density among a collection of candidate density estimators....

Comparison of discrimination methods for the classification of tumors using gene expression data (2002)

Rine Dudoit, Jane Fridly, Terence P. Speed

A reliable and precise classi � cation of tumors is essential for successful diagnosis and treatment of cancer. cDNA microarrays and highdensity oligonucleotide chips are novel biotechnologies...

Statistical methods for identifying differentially expressed genes in replicated cDNA microarray experiments (2002)

Rine Dudoit, Yee Hwa Yang, Matthew J. Callow, Terence P. Speed

Abstract: DNA microarrays are a new and promising biotechnology whichallows the monitoring of expression levels in cells for thousands of genes simultaneously. The present paper describes statistical...

Statistical methods for identifying dierentially expressed genes in replicated cDNA microarray experiments (2002)

Sandrine Dudoit Yeehwayang, Rine Dudoit, Matthew J. Callow, Terence P. Speed, Sandrine Dudoit

Microarrays are part of a new class of biotechnologies which allow the monitoring of expression levels for thousands of genes simultaneously. This paper describes statistical methods for the...

from (1998)

Rine Dudoit, Terence P. Speed

score test for linkage using identity by descent data