Nawtaisong, Pruksa, Keith, James, Fraser, Tresa, Balaraman, Velmurugan, Kolokoltsov, Andrey, Davey, Robert A, ...
Abstract Outbreaks of Dengue impose a heavy economic burden on developing countries in terms of vector control and human morbidity. Effective vaccines against all four serotypes of Dengue are in...
Robert Baxter, Robert A. Davey, David Henty
We examine work carried out at Edinburgh Parallel Computing Centre relevant to parallel unstructured mesh applications of the type commonly encountered in Finite Element and Finite Volume...
Simmons, Anthony, Whitehead, Robert P, Kolokoltsov, Andrey A, Davey, Robert A
Abstract Background Genetic redirection of lymphocytes that have been genetically engineered to recognize antigens other than those originally programmed in their germlines is a potentially powerful...
Unstructured Mesh Libraries for the AP1000 (1996)
Dr Robert, M. Baxter, Robert A. Davey
We present the results from the final year of a three-year collaborative project between Fujitsu Laboratories and Edinburgh Parallel Computing Centre. We have developed and extended a suite of...
Barnett, Anna L., Davey, Robert A., Cunningham, James M.
Retrovirus infection is initiated by receptor-dependent fusion of the envelope to the cell membrane. The modular organization of the envelope protein of C type retroviruses has been exploited to...
Identification of a Receptor-Binding Pocket on the Envelope Protein of Friend Murine Leukemia Virus
Davey, Robert A., Zuo, Yi, Cunningham, James M.
Based on previous structural and functional studies, a potential receptor-binding site composed of residues that form a pocket at one end of the two long antiparallel helices in the receptor-binding...
Kolokoltsov, Andrey A., Davey, Robert A.
We describe a novel assay that permits measurement of entry of murine leukemia virus and pseudotypes with greater sensitivity and more rapidly than previously possible. To achieve this, we...
Kolokoltsov, Andrey A., Weaver, Scott C., Davey, Robert A.
Murine oncoretroviruses and lentiviruses pseudotyped with envelope proteins of alphaviruses have shown great potential in providing broad-host-range, stable vectors for gene therapy. Unlike vesicular...
Barnett, Anna L., Davey, Robert A., Cunningham, James M.
Retrovirus infection is initiated by receptor-dependent fusion of the envelope to the cell membrane. The modular organization of the envelope protein of C type retroviruses has been exploited to...
Identification of a Receptor-Binding Pocket on the Envelope Protein of Friend Murine Leukemia Virus
Davey, Robert A., Zuo, Yi, Cunningham, James M.
Based on previous structural and functional studies, a potential receptor-binding site composed of residues that form a pocket at one end of the two long antiparallel helices in the receptor-binding...
Kolokoltsov, Andrey A., Davey, Robert A.
We describe a novel assay that permits measurement of entry of murine leukemia virus and pseudotypes with greater sensitivity and more rapidly than previously possible. To achieve this, we...
Kolokoltsov, Andrey A., Weaver, Scott C., Davey, Robert A.
Murine oncoretroviruses and lentiviruses pseudotyped with envelope proteins of alphaviruses have shown great potential in providing broad-host-range, stable vectors for gene therapy. Unlike vesicular...
Fleming, Elisa H., Kolokoltsov, Andrey A., Davey, Robert A., Nichols, Joan E., Roberts, Norbert J.
Like many enveloped viruses, human respiratory syncytial virus (RSV) assembles at and buds from lipid rafts. Translocation of the envelope proteins to these membrane subdomains is essential for...
Kolokoltsov, Andrey A., Deniger, Drew, Fleming, Elisa H., Roberts, Norbert J., Karpilow, Jon M., Davey, Robert A.
Respiratory syncytial virus (RSV) is a common cause of respiratory tract infections in infants and the elderly. Like many other pH-independent enveloped viruses, RSV is thought to enter at the cell...
Phosphoinositide-3 Kinase-Akt Pathway Controls Cellular Entry of Ebola Virus
Saeed, Mohammad F., Kolokoltsov, Andrey A., Freiberg, Alexander N., Holbrook, Michael R., Davey, Robert A.
The phosphoinositide-3 kinase (PI3K) pathway regulates diverse cellular activities related to cell growth, migration, survival, and vesicular trafficking. It is known that Ebola virus requires...
Nawtaisong, Pruksa, Keith, James, Fraser, Tresa, Balaraman, Velmurugan, Kolokoltsov, Andrey, Davey, Robert A, ...
Outbreaks of Dengue impose a heavy economic burden on developing countries in terms of vector control and human morbidity. Effective vaccines against all four serotypes of Dengue are in development,...