Robert C. Nowinski

Monoclonal Antibodies Identify Individual Determinants on Mouse Mammary Tumor Virus Glycoprotein gp52 with Group, Class, or Type Specificity

Massey, Richard J., Arthur, Larry O., Nowinski, Robert C., Schochetman, Gerald

Hybrid cell lines producing monoclonal antibodies against the C3H strain of mouse mammary tumor virus (C3H MMTV) were prepared by the fusion of mouse myeloma cells with the lymphocytes of BALB/c mice...

Chromatographic Separation and Antigenic Analysis of Proteins of the Oncornaviruses II. Mammalian Leukemia-Sarcoma Viruses

Nowinski, Robert C., Fleissner, Erwin, Sarkar, Nurul H., Aoki, Tadao

Proteins of leukemia and sarcoma viruses from the chicken, mouse, hamster, and cat were analyzed by gel filtration in guanidine hydrochloride. The mammalian viruses were found to contain six major...

Serological Analysis of the Deoxyribonucleic Acid Polymerase of Avian Oncornaviruses II. Comparison of Avian Deoxyribonucleic Acid Polymerases

Nowinski, Robert C., Watson, K. F., Yaniv, A., Spiegelman, S.

Monospecific antiserum prepared against the isolated deoxyribonucleic acid (DNA) polymerase of avian myeloblastosis virus (AMV) neutralized the endogenous ribonucleic acid-instructed DNA polymerase...

Cell Surface Antigens Associated with Murine Leukemia Virus: Definition of the GL and GT Antigenic Systems

Nowinski, Robert C., Peters, Elizabeth D.

Two new serological specificities were identified on the surface of murine leukemia virus (MuLV)-infected cells by direct and absorption immunofluorescence tests. Both antigens were detected with...

Helical Nucleocapsid Structure of the Oncogenic Ribonucleic Acid Viruses (Oncornaviruses)

Sarkar, Nurul H., Nowinski, Robert C., Moore, Dan H.

Negative staining of virions and isolated nucleoids from avian myeloblastosis virus, murine leukemia virus, murine mammary tumor virus, and feline leukemia virus reveals common internal structures....

Purification of IMP:Pyrophosphate Phosphoribosyltransferases, Catalytically Incompetent Enzymes in Lesch-Nyhan Disease

Rubin, Charles S., Dancis, Joseph, Yip, Lily C., Nowinski, Robert C., Balis, M. Earl

IMP:pyrophosphate phosphoribosyltransferase (IPPase) (EC 2.4.2.8) has been purified over 7000-fold from human erythrocytes. The purified enzyme moved as a single band on disc electrophoresis....

Serological and Structural Properties of Mason-Pfizer Monkey Virus Isolated from the Mammary Tumor of a Rhesus Monkey

Nowinski, Robert C., Edynak, Eugene, Sarkar, Nurul H.

We describe here serological and structural properties of a virus, Mason-Pfizer Monkey Virus (M-PMV), isolated from a simian mammary tumor. This virus is morphologically similar to the known...

Monoclonal Antibodies Identify Individual Determinants on Mouse Mammary Tumor Virus Glycoprotein gp52 with Group, Class, or Type Specificity

Massey, Richard J., Arthur, Larry O., Nowinski, Robert C., Schochetman, Gerald

Hybrid cell lines producing monoclonal antibodies against the C3H strain of mouse mammary tumor virus (C3H MMTV) were prepared by the fusion of mouse myeloma cells with the lymphocytes of BALB/c mice...

Chromatographic Separation and Antigenic Analysis of Proteins of the Oncornaviruses II. Mammalian Leukemia-Sarcoma Viruses

Nowinski, Robert C., Fleissner, Erwin, Sarkar, Nurul H., Aoki, Tadao

Proteins of leukemia and sarcoma viruses from the chicken, mouse, hamster, and cat were analyzed by gel filtration in guanidine hydrochloride. The mammalian viruses were found to contain six major...

Serological Analysis of the Deoxyribonucleic Acid Polymerase of Avian Oncornaviruses II. Comparison of Avian Deoxyribonucleic Acid Polymerases

Nowinski, Robert C., Watson, K. F., Yaniv, A., Spiegelman, S.

Monospecific antiserum prepared against the isolated deoxyribonucleic acid (DNA) polymerase of avian myeloblastosis virus (AMV) neutralized the endogenous ribonucleic acid-instructed DNA polymerase...

Cell Surface Antigens Associated with Murine Leukemia Virus: Definition of the GL and GT Antigenic Systems

Nowinski, Robert C., Peters, Elizabeth D.

Two new serological specificities were identified on the surface of murine leukemia virus (MuLV)-infected cells by direct and absorption immunofluorescence tests. Both antigens were detected with...

Helical Nucleocapsid Structure of the Oncogenic Ribonucleic Acid Viruses (Oncornaviruses)

Sarkar, Nurul H., Nowinski, Robert C., Moore, Dan H.

Negative staining of virions and isolated nucleoids from avian myeloblastosis virus, murine leukemia virus, murine mammary tumor virus, and feline leukemia virus reveals common internal structures....

Purification of IMP:Pyrophosphate Phosphoribosyltransferases, Catalytically Incompetent Enzymes in Lesch-Nyhan Disease

Rubin, Charles S., Dancis, Joseph, Yip, Lily C., Nowinski, Robert C., Balis, M. Earl

IMP:pyrophosphate phosphoribosyltransferase (IPPase) (EC 2.4.2.8) has been purified over 7000-fold from human erythrocytes. The purified enzyme moved as a single band on disc electrophoresis....

Serological and Structural Properties of Mason-Pfizer Monkey Virus Isolated from the Mammary Tumor of a Rhesus Monkey

Nowinski, Robert C., Edynak, Eugene, Sarkar, Nurul H.

We describe here serological and structural properties of a virus, Mason-Pfizer Monkey Virus (M-PMV), isolated from a simian mammary tumor. This virus is morphologically similar to the known...