Boffetta, Paolo, McLaughlin, Joseph K., Lavecchia, Carlo, Tarone, Robert E., Lipworth, Loren, Blot, William J.
Boffetta, Paolo, McLaughlin, Joseph K, La Vecchia, Carlo, Tarone, Robert E, Lipworth, Loren, Blot, William J
Mortensen, Frank Viborg, Jepsen, Peter, Tarone, Robert E., Funch-Jensen, Peter, Jensen, Lone S., Sørensen, Henrik Toft
Sphincterotomy of the ampulla of Vater—a common diagnostic and therapeutic procedure that is sometimes done during endoscopic retrograde cholangiography (ERC)—allows reflux of intestinal content...
False-Positive Results in Cancer Epidemiology: A Plea for Epistemological Modesty (2008)
Boffetta, Paolo, McLaughlin, Joseph K., La Vecchia, Carlo, Tarone, Robert E., Lipworth, Loren, Blot, William J.
False-positive results are inherent in the scientific process of testing hypotheses concerning the determinants of cancer and other human illnesses. Although much of what is known about the etiology...
Jepsen, Peter, Vilstrup, Hendrik, Tarone, Robert E., Friis, Søren, Sørensen, Henrik Toft
Recent studies from several countries, including the United States, have indicated that the incidence rate of intrahepatic cholangiocarcinoma is increasing while that of extrahepatic...
Risk of Soft Tissue Sarcomas by Individual Subtype in Survivors of Hereditary Retinoblastoma (2007)
Kleinerman, Ruth A., Tucker, Margaret A., Abramson, David H., Seddon, Johanna M., Tarone, Robert E., Fraumeni, Joseph F.
Background Survivors of hereditary retinoblastoma have an increased risk for second malignancies, especially soft tissue sarcomas. However, the risks of individual histologic subtypes of soft tissue...
McLaughlin, Joseph K., Lipworth, Loren, Fryzek, Jon P., Ye, Weimin, Tarone, Robert E., Nyren, Olof
Epidemiologic evidence does not support a consistently increased cancer risk among women with cosmetic breast implants, but few studies have assessed risk beyond 15 years. Swedish women who underwent...
Self-reported Electrical Appliance Use and Risk of Adult Brain Tumors (2005)
Kleinerman, Ruth A., Linet, Martha S., Hatch, Elizabeth E., Tarone, Robert E., Black, Peter M., Selker, Robert G., ...
Electrical appliances produce the highest intensity exposures to residential extremely low frequency electromagnetic fields. The authors investigated whether appliances may be associated with adult...
E. Janet Tawn, Caroline A. Whitehouse, Robert E. Tarone
Tawn, E. J., Whitehouse, C. A. and Tarone, R. E. FISH Chromosome Aberration Analysis on Retired Radiation Workers from the Sellafield Nuclear Facility. Radiat. Res. 162, 249–256 (2004). Chromosome...
E. Janet Tawn, Caroline A. Whitehouse, C. Paul Daniel, Robert E. Tarone, Andrea M. Bothwell, Ann Fisher
Tawn, E. J., Whitehouse, C. A., Daniel, C. P., Tarone, R.;thE., Bothwell, A. M. and Fisher, A. Somatic Cell Mutations at the Glycophorin A Locus in Erythrocytes of Radiation Workers from the...
Doody, Michele Morin, Sigurdson, Alice S., Kampa, Diane, Chimes, Kathleen, Alexander, Bruce H., Ron, Elaine, ...
In a follow-up study, only 64% of 126,628 US radiologic technologists completed a questionnaire during 1994–1997 after two mailings. The authors conducted a randomized trial of financial...
Cancer Risk among Workers at Danish Companies using Trichloroethylene: A Cohort Study (2003)
Raaschou-Nielsen, Ole, Hansen, Johnni, McLaughlin, Joseph K., Kolstad, Henrik, Christensen, Jytte M., Tarone, Robert E., ...
Trichloroethylene is an animal carcinogen with limited evidence of carcinogenicity in humans. Cancer incidence between 1968 and 1997 was evaluated in a cohort of 40,049 blue-collar workers in 347...
Sociodemographic indicators and risk of brain tumours (2003)
Inskip, Peter D, Tarone, Robert E, Hatch, Elizabeth E, Wilcosky, Timothy C, Fine, Howard A, Black, Peter M, ...
Background To better understand patterns of occurrence or diagnosis of brain tumours in different segments of the population, we evaluated associations between sociodemographic variables and the...
Landi, Maria Teresa, Baccarelli, Andrea, Tarone, Robert E., Pesatori, Angela, Tucker, Margaret A., Hedayati, Mohammad, ...
Background: Exposure to UV radiation is associated with cutaneous malignant melanoma (CMM). In mammalian cells, UV radiation induces DNA damage that can be repaired by the nucleotide excision repair...
Landi, Maria Teresa, Baccarelli, Andrea, Pesatori, Angela C., Hedayati, Mohammad, Grossman, Lawrence, Tucker, Margaret A., ...
Cancer in Korean War Navy Technicians: Mortality Survey after 40 Years (2002)
Groves, Frank D., Page, William F., Gridley, Gloria, Lisimaque, Laure, Stewart, Patricia A., Tarone, Robert E., ...
This study reports on over 40 years of mortality follow-up of 40,581 Navy veterans of the Korean War with potential exposure to high-intensity radar. The cohort death rates were compared with...
Wang, Wendy. W., Spurdle, Amanda. B., Kolachana, Prema, Bove, Betsy, Modan, Baruch, Ebbers, Sarah. M., ...
Wang, Wendy. W., Spurdle, Amanda. B., Kolachana, Prema, Bove, Betsy, Modan, Baruch, Ebbers, Sarah. M., ...
Bowman, Joseph D., Thomas, Duncan C., Kleinerman, Ruth A., Linet, Martha S., Tarone, Robert E., Wacholder, Sholom, ...
Recent Trends in Lung Cancer Mortality in the United States (2001)
Jemal, Ahmedin, Chu, Kenneth C., Tarone, Robert E.
Background: Previous age–period–cohort analyses of lung cancer incidence and mortality rates in the United States have demonstrated a decrease in risk by birth cohort through 1950, consistent...
Larry W. Figgs, Nina Titenko Holl, Nathanial Rothman, Shelia Hoar Zahm, Robert E. Tarone, Robert Hill, ...
Objective: Evaluate peripheral blood lymphocyte proliferation (replicative index:RI) and micronuclei frequency (MF) among 2,4-D herbicide applicators. Methods: Twelve applicators spraying only 2,4-D...
Auvinen, Anssi, Linet, Martha S., Hatch, Elizabeth E., Kleinerman, Ruth A., Robison, Leslie L., Kaune, William T., ...
Data collected by the National Cancer Institute-Children's Cancer Group were utilized to explore various metrics of magnetic field levels and risk of acute lymphoblastic leukemia (ALL) in children....
Hereditary Retinoblastoma and Risk of Lung Cancer (2000)
Kleinerman, Ruth A., Tarone, Robert E., Abramson, David H., Seddon, Johanna M., Li, Frederick P., Tucker, Margaret A.
Kleinerman, Ruth A., Kaune, William T., Hatch, Elizabeth E., Wacholder, Sholom, Linet, Martha S., Robison, Leslie L., ...
In the National Cancer Institute/Children's Cancer Group case-control study of childhood acute lymphoblastic leukemia (1989–1993), living in a home with a high-voltage wire code was not...
A new xeroderma pigmentosum group C poly(AT) insertion/deletion polymorphism (2000)
Khan, Sikandar G., Metter, E.Jeffrey, Tarone, Robert E., Bohr, Vilhelm A., Grossman, Lawrence, Hedayati, Mohammad, ...
We found a common biallelic polymorphism (PAT) in the xeroderma pigmentosum complementation group C (XPC) DNA repair gene consisting of an insertion of 83 bases of A and T [poly(AT)] and a...
Alternate Ranging Methods for Cancer Mortality Maps (2000)
Grauman, Dan J., Tarone, Robert E., Devesa, Susan S., Fraumeni, Joseph F.
Background: Mapping techniques can highlight the spatial or temporal variations in rates of cancer mortality. In mapping geographic patterns of cancer mortality, spatial units are grouped into...
Linet, Martha S., Ries, Lynn A. G., Smith, Malcolm A., Tarone, Robert E., Devesa, Susan S.
BACKGROUND: Public concern about possible increases in childhood cancer incidence in the United States led us to examine recent incidence and mortality patterns. METHODS: Cancers diagnosed in...
Evaluation of Birth Cohort Patterns in Population Disease Rates (1996)
Tarone, Robert E., Chu, Kenneth C.
Interpretation of trends in disease rates using conventional age-period-cohort analyses is made difficult by the lack of a unique set of parameters specifying any given model. Because of difficulties...
Recent Trends in U.S. Breast Cancer Incidence, Survival, and Mortality Rates (1996)
Chu, Kenneth C., Tarone, Robert E., Kessler, Larry G., Ries, Lynn A. G., Hankey, Benjamin F., Miller, Barry A., ...
Background: Clinical trials have demonstrated that use of mammographic screening and advances in therapy can improve prognosis for women with breast cancer. Purpose: We determined the trends in...
Recent Cancer Trends in the United States (1995)
Devesa, Susan S., Blot, William J., Stone, B. J., Miller, Barry A., Tarone, Robert E., Fraumeni, Joseph F.
Background: Cancer incidence rates have been reported to be increasing in the United States, although trends vary according to form of cancer. Purpose: We identify the cancers accounting for the...
Chu, Kenneth C., Tarone, Robert E., Chow, Wong-Ho, Hankey, Benjamin F., Ries, Lynn A. Gloeckler
Background Colorectal cancer mortality rates among U.S. white males remained relatively constant from 1950 through 1984 but declined sharply from 1985 through 1990. Those for U.S. white females...
Parshad, Ram, Sanford, Katherine K., Price, Floyd M., Rhim, Johng S., Tarone, Robert E., Fusenig, Norbert E., ...
Human skin keratinocytes after malignant neoplastic transformation by infection with Kirsten murine sarcoma virus (KiMSV) or transfection with pSV2 ras (containing an activated c-Ha-ras oncogene)...
Implications of Birth Cohort Patterns in Interpreting Trends in Breast Cancer Rates (1992)
Tarone, Robert E., Chu, Kenneth C.
Background: Most investigations of trends in cancer rates are based on a cross-sectional approach, i.e., an examination of trend in rates by year of diagnosis or death. When there are longitudinal...
ROBBINS, JAY H., BRUMBACK, ROGER A., MENDIONES, MARLENE, BARRETT, SUSANNA F., CARL, JAMES R., CHO, SECHIN, ...
Xeroderma pigmentosum (XP) is an autosomal recessive, neurocutaneous disorder characterized by sunlight-induced skin cancers and defective DNA repair. Many XP children develop a primary neuronal...
Hayes, Howard M., Tarone, Robert E., Cantor, Kenneth P., Jessen, Carl R., McCurnin, Dennis M., Richardson, Ralph C.
A hospital-based case-control study of companion dogs examined the risk of developing canine malignant lymphoma associated with the use of chemicals in and about the home. Information from a...
Excess of Seminomas Observed in Vietnam Service U.S. Military Working Dogs (1990)
Hayes, Howard M., Tarone, Robert E., Casey, Harold W., Huxsoll, David L.
During the Vietnam War, US military working dogs served with their companion dog handlers in close proximity, sharing common exposures to war-related activity, many zoonotic infectious agents,...
Sanford, Katherine K., Parshad, Ram, Price, Floyd M., Jones, Gary M., Tarone, Robert E., Eierman, Lindsay, ...
An assay for ataxia-telangiectasia (A-T) heterozygotes, i.e., healthy carriers of the A-T gene(s), requiring only a small sample (3.5 mL) of peripheral blood, is described. Frequencies of chromatid...
Takai, Setsuo, Floyd, M.Price, Sanford, Katherine K., Tarone, Robert E., Parshad, Ram
Previous reports showed that skin fibroblasts or peripheral blood lymphocytes from individuals with hereditary cancer or with a genetic disorder predisposing to cancer show an abnormally high...
Enhanced Malignant Conversion of Benign Mouse Skin Tumors by Cisplatin (1990)
Hennings, Henry, Shores, Robert A., Poirier, Miriam C., Reed, Eddie, Tarone, Robert E., Yuspa, Stuart H.
The chemotherapeutic agent cisplatin, reported to be a complete carcinogen in rodents and a tumor initiator for mouse skin, was tested for activity to enhance the conversion of carcinogen-induced...
Deficient G2 phase repair of radiation-induced chromatin damage in the SENCAR mouse (1989)
Sanford, Katherine K., Parshad, Ram, Price, Floyd M., Gantt, Raymond, Jones, Gary M., Tarone, Robert E.
The SENCAR mouse, selectively bred for sensitivity to skin tumor induction by two-stage chemical carcinogenesis, is also genetically hypersensitive to skin carcinogenesis by high doses of UV. Skin...
Chu, Kenneth C., Smart, Charles R., Tarone, Robert E.
The Health Insurance Plan (HIP) of Greater New York conducted a clinical trial to determine if screening for breast cancer with mammography and clinical examination would decrease breast cancer...
CAMERON, THOMAS P., HICKMAN, ROBERT L., KORNREICH, MARY R., TARONE, ROBERT E.
History, Survival, and Growth Patterns of B6C3F1 Mice and F344 Rats in the National Cancer Institute Carcinogenesis Testing Program. CAMERON, T. P., HICKMAN, R. L., KORNREICH, M. R., AND TARONE, R....
On heterogeneity tests based on efficient scores (1985)
For cases in which a parameter may be estimated from several independent data sets, Mather (1935) proposed a heterogeneity test based on the efficient scores for the individual data sets evaluated at...
TARONE, ROBERT E., GART, JOHN J., HAUCK, WALTER W.
Nurminen (1981) gives conditions for the asymptotic efficiency of general weighted mean estimators. His application is a noniterative estimator of a common relative risk for binomial variates. This...
BLADDER CANCER IN PET DOGS: A SENTINEL FOR ENVIRONMENTAL CANCER? (1981)
HAYES, HOWARD M., HOOVER, ROBERT, TARONE, ROBERT E.
Proportional morbidity ratios (PMRs) were calculated for cancers, by site or type, in 8760 pet dogs seen at 13 veterinary medical teaching hospitals in the United States and Canada. A significant...
On distribution-free tests for equality of survival distributions (1977)
TARONE, ROBERT E., WARE, JAMES
Two statistics for testing the equality of survival distributions in the presence of arbitarry right censorship, the log rank test statistic and the modified Wilcoxon test statictic, are shown to...
Tests for trend in life table analysis (1975)
Using the regression model proposed by Cox (1972) a test for monotone trend in hazard functions is derived for use, for example, in chemical carcinogenesis experiments in which a chemical is...
Winter, David B., Phung, Quy H., Umar, Asad, Baker, Sean M., Tarone, Robert E., Tanaka, Kiyoji, ...
Mutations are introduced into rearranged Ig variable genes at a frequency of 10−2 mutations per base pair by an unknown mechanism. Assuming that DNA repair pathways generate or remove mutations,...
Winter, David B., Phung, Quy H., Umar, Asad, Baker, Sean M., Tarone, Robert E., Tanaka, Kiyoji, ...
Mutations are introduced into rearranged Ig variable genes at a frequency of 10−2 mutations per base pair by an unknown mechanism. Assuming that DNA repair pathways generate or remove mutations,...
Rosner, Karli, Winter, David B, Tarone, Robert E, Skovgaard, Gunhild Lange, Bohr, Vilhelm A, Gearhart, Patricia J
The third complementarity-determining region (CDR3) of immunoglobulin variable genes for the heavy chain (VH) has been shown to be shorter in length in hypermutated antibodies than in...
Perfluorinated Chemicals and Fetal Growth: A Study within the Danish National Birth Cohort
Fei, Chunyuan, McLaughlin, Joseph K., Tarone, Robert E., Olsen, Jørn
Phung, Quy H., Winter, David B., Cranston, Aaron, Tarone, Robert E., Bohr, Vilhelm A., Fishel, Richard, ...
Rearranged immunoglobulin variable genes are extensively mutated after stimulation of B lymphocytes by antigen. Mutations are likely generated by an error-prone DNA polymerase, and the mismatch...
False-Positive Results in Cancer Epidemiology: A Plea for Epistemological Modesty
Boffetta, Paolo, McLaughlin, Joseph K., La Vecchia, Carlo, Tarone, Robert E., Lipworth, Loren, Blot, William J.
False-positive results are inherent in the scientific process of testing hypotheses concerning the determinants of cancer and other human illnesses. Although much of what is known about the etiology...