Walter, Nicole AR, Bottomly, Daniel, Laderas, Ted, Mooney, Michael A, Darakjian, Priscila, Searles, Robert P, ...
Abstract Background Allelic variation is the cornerstone of genetically determined differences in gene expression, gene product structure, physiology, and behavior. However, allelic variation,...
Original Contributions Fine scale mapping of a genetic locus for conditioned fear (2007)
Christopher J. Talbot, Richard A. Radcliffe, Jan Fullerton, Robert Hitzemann, Jeanne M. Wehner, Jonathan Flint
Fear conditioning is one of a number of models for investigating the genetic basis of individual variation in emotion and learning. Genetic mapping using crosses between strains of laboratory mice...
The Collaborative Cross, a community resource for the genetic analysis of complex traits (2004)
Churchill, Gary A., Airey, David C., Allayee, Hooman, Angel, Joe M., Attie, Alan D., Beatty, Jackson, ...
The goal of the Complex Trait Consortium is to promote the development of resources that can be used to understand, treat and ultimately prevent pervasive human diseases. Existing and proposed mouse...
The nature and identification of quantitative trait loci: a community’s view (2003)
Rosemann, Michael, Pomp, Daniel, Peirce, Jeremy L., Palmer, Abraham A., Paigen, Beverly, Osadchuk, Alexander V., ...
This white paper by eighty members of the Complex Trait Consortium presents a community’s view on the approaches and statistical analyses that are needed for the identification of genetic loci that...
Fine scale mapping of a genetic locus for conditioned fear (2003)
Talbot, Christopher J., Radcliffe, R.A., Fullerton, J., Hitzemann, Robert, Wehner, J.M., Flint, J.
A strategy for the integration of QTL, gene expression, and sequence analyses (2003)
Hitzemann, Robert, Malmanger, B., Reed, C., Lawler, M., Hitzemann, Barbara, Coulombe, S., ...
John K. Belknap, Robert Hitzemann, John C. Crabbe, Tamara J. Phillips, Kari J. Buck, Robert W. Williams, ...
Quantitative genetics and QTL mapping have undergone a revolution in the last decade. Progress in the next decade promises to be at least as rapid, and strategies for fine mapping QTLs and...
Goldstein, Rita Z., Leskovjan, Andreana C., Hoff, Anne L., Hitzemann, Robert, Bashan, Francine, Khalsa, Sahib Singh, ...
We used exploratory and confirmatory statistical approaches to study the severity of neuropsychological (NP) impairment in 42 crack/cocaine addicted subjects and in 112 comparison subjects (40...
Anger and depression in cocaine addiction: association with the orbitofrontal cortex
Goldstein, Rita Z., Alia-Klein, Nelly, Leskovjan, Andreana C., Fowler, Joanna S., Wang, Gene-Jack, Gur, Ruben C., ...
The high prevalence of anger, impulsivity and violence in cocaine addiction implicates chronic cocaine use in the compromise of higher-order inhibitory control neurocognitive processes. We used the...