Robert Ian Richards

Contribution of mGluR and Fmr1 functional pathways to neurite morphogenesis, craniofacial development and fragile X syndrome (2006)

Tucker, Ben, Richards, Robert Ian, Lardelli, Michael Trent

Fragile X Syndrome is a leading heritable cause of mental retardation that results from the loss of FMR1 gene function. Studies in mouse and Drosophila model organisms have been critical in...

Contribution of mGluR and Fmr1 functional pathways to neurite morphogenesis, craniofacial development and fragile X syndrome (2006)

Tucker, Ben, Richards, Robert Ian, Lardelli, Michael Trent

Fragile X Syndrome is a leading heritable cause of mental retardation that results from the loss of FMR1 gene function. Studies in mouse and Drosophila model organisms have been critical in...

Common chromosomal fragile site FRA16D mutation in cancer cells (2005)

Finnis, M., Dayan, S., Hobson, L., Chenevix-Trench, G., Friend, K. L., Ried, Karin, ...

Neither the molecular basis for common fragile site DNA instability nor the contribution of this form of chromosomal instability to cancer is clearly understood. Fragile site FRA16D (16q23.2) is...

The pathogenic agent in Drosophila models of 'polyglutamine' diseases (2005)

McLeod, Catherine Jean, O'Keefe, Louise Veronica, Richards, Robert Ian

A substantial body of evidence supports the identity of polyglutamine as the pathogenic agent in a variety of human neurodegenerative disorders where the mutation is an expanded CAG repeat. However,...

FRA16D common chromosomal fragile site oxido-reductase (FOR/WWOX) protects against the effects of ionizing radiation in Drosophila (2005)

O'Keefe, Louise Veronica, Liu, Yinghong, Perkins, A. J., Dayan, Sonia, Saint, Robert Bryce, Richards, Robert Ian

Fragile sites are chromosomal structures that have been proposed to have a determining role in cancer-associated DNA instability. The human WWOX gene spans the FRA16D chromosomal fragile site, the...

FRA16D common chromosomal fragile site oxido-reductase (FOR/WWOX) protects against the effects of ionizing radiation in Drosophila (2005)

O’Keefe, Louise Veronica, Liu, Y-H., Perkins, A., Dayan, S., Saint, Robert Bryce, Richards, Robert Ian

Fragile sites are chromosomal structures that have been proposed to have a determining role in cancer associated DNA instability. The human WWOX gene spans the FRA16D chromosomal fragile site, the...

Common chromosomal fragile site FRA16D mutation in cancer cells (2005)

Finnis, M., Dayan, S., Hobson, L., Chenevix-Trench, G., Friend, K. L., Ried, Karin, ...

Neither the molecular basis for common fragile site DNA instability nor the contribution of this form of chromosomal instability to cancer is clearly understood. Fragile site FRA16D (16q23.2) is...

The pathogenic agent in Drosophila models of 'polyglutamine' diseases (2005)

McLeod, Catherine Jean, O'Keefe, Louise Veronica, Richards, Robert Ian

A substantial body of evidence supports the identity of polyglutamine as the pathogenic agent in a variety of human neurodegenerative disorders where the mutation is an expanded CAG repeat. However,...

FRA16D common chromosomal fragile site oxido-reductase (FOR/WWOX) protects against the effects of ionizing radiation in Drosophila (2005)

O'Keefe, Louise Veronica, Liu, Yinghong, Perkins, A. J., Dayan, Sonia, Saint, Robert Bryce, Richards, Robert Ian

Fragile sites are chromosomal structures that have been proposed to have a determining role in cancer-associated DNA instability. The human WWOX gene spans the FRA16D chromosomal fragile site, the...

FRA16D common chromosomal fragile site oxido-reductase (FOR/WWOX) protects against the effects of ionizing radiation in Drosophila (2005)

O’Keefe, Louise Veronica, Liu, Y-H., Perkins, A., Dayan, S., Saint, Robert Bryce, Richards, Robert Ian

Fragile sites are chromosomal structures that have been proposed to have a determining role in cancer associated DNA instability. The human WWOX gene spans the FRA16D chromosomal fragile site, the...

Autosomal dominant congenital non-progressive ataxia overlaps with the SCA15 locus (2004)

Dudding, T. E., Friend, K. L., Schofield, P. R., Lee, S., Wilkinson, I., Richards, Robert Ian

Background: Most patients with pure nonprogressive congenital cerebellar ataxia have a sporadic form of unknown heredity and etiology. Several small families have been reported with a dominantly...

Dynamic mutations on the move in Banff (2004)

La Spada, A. R., Richards, Robert Ian, Wieringa, B.

The mechanisms involved in microsatellite repeat instability and the consequent pathways that lead to disease have fascinated investigators from a wide range of disciplines for over a decade. This...

Autosomal dominant congenital non-progressive ataxia overlaps with the SCA15 locus (2004)

Dudding, T. E., Friend, K. L., Schofield, P. R., Lee, S., Wilkinson, I., Richards, Robert Ian

Background: Most patients with pure nonprogressive congenital cerebellar ataxia have a sporadic form of unknown heredity and etiology. Several small families have been reported with a dominantly...

Dynamic mutations on the move in Banff (2004)

La Spada, A. R., Richards, Robert Ian, Wieringa, B.

The mechanisms involved in microsatellite repeat instability and the consequent pathways that lead to disease have fascinated investigators from a wide range of disciplines for over a decade. This...

Fragile and unstable chromosomes in cancer: causes and consequences (2001)

Richards, Robert Ian

Cancer cells commonly exhibit various forms of genetic instability, such as changes in chromosome copy number, translocations and point mutations in particular genes. Although transmissible change...

Dynamic mutations (2001)

Richards, Robert Ian, Sutherland, G. R.

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Fragile X Syndrome (2001)

Sutherland, G. R., Richards, Robert Ian

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Fragile and unstable chromosomes in cancer: causes and consequences (2001)

Richards, Robert Ian

Cancer cells commonly exhibit various forms of genetic instability, such as changes in chromosome copy number, translocations and point mutations in particular genes. Although transmissible change...

Dynamic mutations (2001)

Richards, Robert Ian, Sutherland, G. R.

http://proxy.library.adelaide.edu.au/login?url=http://library.adelaide.edu.au/cgi-bin/Pwebrecon.cgi?BBID=641191

Fragile X Syndrome (2001)

Sutherland, G. R., Richards, Robert Ian

http://proxy.library.adelaide.edu.au/login?url=http://library.adelaide.edu.au/cgi-bin/Pwebrecon.cgi?BBID=1112099

Chromosomal fragile site FRA16D and DNA instability in cancer (2000)

Mangelsdorf, Marie Elise, Ried, Karin, Woollatt, E., Dayan, S., Eyre, H., Finnis, M. L., ...

It has been proposed that common aphidicolin-inducible fragile sites, in general, predispose to specific chromosomal breakage associated with deletion, amplification, and/or translocation in certain...

Chromosomal fragile site FRA16D and DNA instability in cancer (2000)

Mangelsdorf, Marie Elise, Ried, Karin, Woollatt, E., Dayan, S., Eyre, H., Finnis, M. L., ...

It has been proposed that common aphidicolin-inducible fragile sites, in general, predispose to specific chromosomal breakage associated with deletion, amplification, and/or translocation in certain...