Scientific Commons: Robert W. Milne

Renal Disposition of Colistin in the Isolated Perfused Rat Kidney (2009)

Ma, Zheng, Wang, Jiping, Nation, Roger L., Li, Jian, Turnidge, John Douglas, Coulthard, Kingsley, ...

Zheng Ma, Jiping Wang, Roger L. Nation, Jian Li, John D. Turnidge, Kingsley Coulthard, and Robert W. Milne

Renal Disposition of Colistin in the Isolated Perfused Rat Kidney (2009)

Ma, Zheng, Wang, Jiping, Nation, Roger L., Li, Jian, Turnidge, John Douglas, Coulthard, Kingsley, ...

Zheng Ma, Jiping Wang, Roger L. Nation, Jian Li, John D. Turnidge, Kingsley Coulthard, and Robert W. Milne

Comparison of once-, twice- and thrice-daily dosing of colistin on antibacterial effect and emergence of resistance: studies with Pseudomonas aeruginosa in an in vitro pharmacodynamic model (2008)

Bergen, Phillip J., Li, Jian, Nation, Roger L., Turnidge, John D., Coulthard, Kingsley, Milne, Robert W.

Objectives The optimal dosing regimen for colistin methanesulphonate (CMS) against Pseudomonas aeruginosa is unknown. CMS is converted in vivo to its active form, colistin. We evaluated three...

Subacute toxicity of colistin methanesulfonate in rats: Comparison of various intravenous dosage regimens (2008)

Wallace, Stephanie J., Li, Jian, Nation, Roger L., Rayner, Craig R., Taylor, David, Middleton, Deborah, ...

Stephanie J. Wallace, Jian Li, Roger L. Nation, Craig R. Rayner, David Taylor, Deborah Middleton, Robert W. Milne, Kingsley Coulthard, and John D. Turnidge

Subacute toxicity of colistin methanesulfonate in rats: Comparison of various intravenous dosage regimens (2008)

Wallace, Stephanie J., Li, Jian, Nation, Roger L., Rayner, Craig R., Taylor, David, Middleton, Deborah, ...

Stephanie J. Wallace, Jian Li, Roger L. Nation, Craig R. Rayner, David Taylor, Deborah Middleton, Robert W. Milne, Kingsley Coulthard, and John D. Turnidge

Comparison of once-, twice- and thrice-daily dosing of colistin on antibacterial effect and emergence of resistance: studies with Pseudomonas aeruginosa in an in vitro pharmacodynamic model (2008)

Bergen, Phillip J., Li, Jian, Nation, Roger L., Turnidge, John Douglas, Coulthard, Kingsley, Milne, Robert W.

Steady-state pharmacokinetics of the enantiomers of perhexiline in CYP2D6 poor and extensive metabolizers administered Rac-perhexiline (2008)

Davies, Benjamin James Lloyd, Herbert, Megan K., Coller, Janet Kristie, Somogyi, Andrew Alexander, Milne, Robert W., Sallustio, Benedetta Cristina

The definitive version may be found at www.wiley.com

Comparison of once-, twice- and thrice-daily dosing of colistin on antibacterial effect and emergence of resistance: studies with Pseudomonas aeruginosa in an in vitro pharmacodynamic model (2008)

Bergen, Phillip J., Li, Jian, Nation, Roger L., Turnidge, John Douglas, Coulthard, Kingsley, Milne, Robert W.

Steady-state pharmacokinetics of the enantiomers of perhexiline in CYP2D6 poor and extensive metabolizers administered Rac-perhexiline (2008)

Davies, Benjamin James Lloyd, Herbert, Megan K., Coller, Janet Kristie, Somogyi, Andrew Alexander, Milne, Robert W., Sallustio, Benedetta Cristina

The definitive version may be found at www.wiley.com

Effect of CYP2D6 metabolizer status on the disposition of the (+) and (-) enantiomers of perhexiline in patients with myocardial ischaemia (2007)

Inglis, Sally Catherine, Herbert, Megan K., Davies, Benjamin James Lloyd, Coller, Janet Kristie, James, Heather M., Horowitz, John David, ...

Sally C. Inglis; Megan K. Herbert; Benjamin J.L. Davies; Janet K. Coller; Heather M. James; John D. Horowitz; Raymond G. Morris; Robert W. Milne; Andrew A. Somogyi; Benedetta C. Sallustio

CYP2B6 CYP2D6 and CYP3A4 catalyze the primary oxidative metabolism of perhexiline enantiomers by human liver microsomes (2007)

Davies, Benjamin James Lloyd, Coller, Janet Kristie, Somogyi, Andrew Alexander, Milne, Robert W., Sallustio, Benedetta Cristina

Effect of CYP2D6 metabolizer status on the disposition of the (+) and (-) enantiomers of perhexiline in patients with myocardial ischaemia (2007)

Inglis, Sally Catherine, Herbert, Megan K., Davies, Benjamin James Lloyd, Coller, Janet Kristie, James, Heather M., Horowitz, John David, ...

Sally C. Inglis; Megan K. Herbert; Benjamin J.L. Davies; Janet K. Coller; Heather M. James; John D. Horowitz; Raymond G. Morris; Robert W. Milne; Andrew A. Somogyi; Benedetta C. Sallustio

CYP2B6 CYP2D6 and CYP3A4 catalyze the primary oxidative metabolism of perhexiline enantiomers by human liver microsomes (2007)

Davies, Benjamin James Lloyd, Coller, Janet Kristie, Somogyi, Andrew Alexander, Milne, Robert W., Sallustio, Benedetta Cristina

Accumulation of trimethylamine and trimethylamine-N-oxide in end-stage renal disease patients undergoing haemodialysis (2006)

Bain, Marcus A., Faull, Randall, Fornasini, Gianfranco, Milne, Robert W., Evans, Allan M.

Background. Trimethylamine (TMA) is a short-chain tertiary aliphatic amine that is derived from the diet either directly from the consumption of foods high in TMA or by the intake of food high in...

Accumulation of trimethylamine and trimethylamine-N-oxide in end-stage renal disease patients undergoing haemodialysis (2006)

Bain, Marcus A., Faull, Randall, Fornasini, Gianfranco, Milne, Robert W., Evans, Allan M.

Background. Trimethylamine (TMA) is a short-chain tertiary aliphatic amine that is derived from the diet either directly from the consumption of foods high in TMA or by the intake of food high in...

Accumulation of trimethylamine and trimethylamine-N-oxide in end-stage renal disease patients undergoing haemodialysis (2006)

Bain, Marcus A., Faull, Randall, Fornasini, Gianfranco, Milne, Robert W., Evans, Allan M.

Background. Trimethylamine (TMA) is a short-chain tertiary aliphatic amine that is derived from the diet either directly from the consumption of foods high in TMA or by the intake of food high in...

Accumulation of trimethylamine and trimethylamine-N-oxide in end-stage renal disease patients undergoing haemodialysis (2006)

Bain, Marcus A., Faull, Randall, Fornasini, Gianfranco, Milne, Robert W., Evans, Allan M.

Background. Trimethylamine (TMA) is a short-chain tertiary aliphatic amine that is derived from the diet either directly from the consumption of foods high in TMA or by the intake of food high in...

Pharmacokinetics of colistin methanesulphonate and colistin in rats following an intravenous dose of colistin methanesulphonate (2004)

Li, Jian, Milne, Robert W., Nation, Roger L., Turnidge, John D., Smeaton, Timothy C., Coulthard, Kingsley

Objectives: To determine the disposition of colistin methanesulphonate (CMS) and colistin following intravenous (iv) administration of CMS in rats. Methods: Five rats received a single iv bolus of 15...

Pharmacokinetics of colistin methanesulphonate and colistin in rats following an intravenous dose of colistin methanesulphonate (2004)

Li, Jian, Milne, Robert W., Nation, Roger L., Turnidge, John D., Smeaton, Timothy C., Coulthard, Kingsley

Objectives: To determine the disposition of colistin methanesulphonate (CMS) and colistin following intravenous (iv) administration of CMS in rats. Methods: Five rats received a single iv bolus of 15...

A small-scale synthesis and enantiomeric resolution of (RS)-[1-C-14]-2-phenylpropionic acid and biosynthesis of its diastereomeric acyl glucuronides (2001)

Shackleford, David M., Hayball, Peter J., Reynolds, Geoffrey D., Hamon, David P.G., Evans, Allan M., Milne, Robert W., ...

David M. Shackleford, Peter J. Hayball, Geoffrey D. Reynolds, David P.G. Hamon, Allan M. Evans, Robert W. Milne, Roger L. Nation

A small-scale synthesis and enantiomeric resolution of (RS)-[1-C-14]-2-phenylpropionic acid and biosynthesis of its diastereomeric acyl glucuronides (2001)

Shackleford, David M., Hayball, Peter J., Reynolds, Geoffrey D., Hamon, David P.G., Evans, Allan M., Milne, Robert W., ...

David M. Shackleford, Peter J. Hayball, Geoffrey D. Reynolds, David P.G. Hamon, Allan M. Evans, Robert W. Milne, Roger L. Nation

The disposition of morphine and its 3- and 6-glucuronide metabolites in humans and sheep / Robert W. Milne. (1994)

Milne, Robert W. (Robert William).