Apes, lice and prehistory (2009)
Abstract Although most epidemic human infectious diseases are caused by recently introduced pathogens, cospeciation of parasite and host is commonplace for endemic infections. Occasional host...
Longitudinally Profiling Neutralizing Antibody Response to SARS (2008)
Coronavirus Pseudotypes, Nigel J. Temperton, Paul K. Chan, Graham Simmons, Maria C. Zambon, Richard S. Tedder, ...
The severe acute respiratory syndrome–associated coronavirus (SARS-CoV) spike protein (S) is a major target for neutralizing antibodies. Retroviral SARS-CoV S pseudotypes have been constructed and...
He, Weijing, Neil, Stuart, Kulkarni, Hemant, Wright, Edward, Agan, Brian K, Marconi, Vincent C, ...
Duffy antigen receptor for chemokines (DARC) expressed on red blood cells (RBCs) influences plasma levels of HIV-1-suppressive and proinflammatory chemokines such as CCL5/RANTES. DARC is also the RBC...
A sexually transmitted parasitic cancer (2006)
Weiss, Robin A, Fassati, Ariberto, Murgia, Claudio
No abstract available.
The discovery of endogenous retroviruses (2006)
Abstract When endogenous retroviruses (ERV) were discovered in the late 1960s, the Mendelian inheritance of retroviral genomes by their hosts was an entirely new concept. Indeed Howard M Temin's DNA...
AIDS and HIV infection: New perspectives (1988)
Pinching, Anthony J, Weiss, Robin A, Miller, David
This volume examines the emerging pandemic of AIDS and HIV infection from a broad perspective, in particular examing the epidemiological and clinical features and its wider impact and highlighting...
The virology of human immunodeficiency viruses (1988)
Weber, Jonathan N, Weiss, Robin A
This chapter describes in detail the nature and diversity of currently recognised human immunodeficiency viruses (HIVs). It goes on to describe their genomic organisation and relates these to the...
Dupin, Nicolas, Fisher, Cyril, Kellam, Paul, Ariad, Sam, Tulliez, Micheline, Franck, Nathalie, ...
Human herpesvirus 8 (HHV-8, also called KSHV) is linked to the etiopathogenesis of Kaposi’s sarcoma (KS), multicentric Castleman’s disease (MCD), and primary effusion lymphoma (PEL). The...
Patience, Clive, Takeuchi, Yasuhiro, Cosset, Francois-Loic, Weiss, Robin A.
Interaction of retrovirus vectors and endogenous retroviruses present in packaging cell lines and target cells may result in unwanted events, such as the formation of recombinant viruses and the...
Host Range and Interference Studies of Three Classes of Pig Endogenous Retrovirus
Takeuchi, Yasuhiro, Patience, Clive, Magre, Saema, Weiss, Robin A., Banerjee, Papia T., Le Tissier, Paul, ...
Recent interest in the use of porcine organs, tissues, and cells for xenotransplantation to humans has highlighted the need to characterize the properties of pig endogenous retroviruses (PERVs)....
Virus Load and Sequence Variation in Simian Retrovirus Type 2 Infection
Rosenblum, Lisa L., Weiss, Robin A., McClure, Myra O.
The natural history of type D simian retrovirus (SRV) infection is poorly characterized in terms of viral load, antibody status, and sequence variation. To investigate this, blood samples were taken...
Morozov, Vladimir A., Lagaye, Sylvie, Taylor, Graham P., Matutes, Estella, Weiss, Robin A.
Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia/lymphoma (ATLL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and other diseases....
Kellam, Paul, Bourboulia, Dimitra, Dupin, Nicolas, Shotton, Chris, Fisher, Cyril, Talbot, Simon, ...
Human herpesvirus 8 (HHV-8; also designated Kaposi’s sarcoma-associated herpesvirus) is the likely etiological agent of Kaposi’s sarcoma (KS). HHV-8 encodes a latent nuclear antigen (LNA) which...
Susceptibility of the Porcine Endogenous Retrovirus to Reverse Transcriptase and Protease Inhibitors
Qari, Shoukat H., Magre, Saema, García-Lerma, J. Gerardo, Hussain, Althaf I., Takeuchi, Yasuhiro, Patience, Clive, ...
Porcine xenografts may offer a solution to the shortage of human donor allografts. However, all pigs contain the porcine endogenous retrovirus (PERV), raising concerns regarding the transmission of...
Multiple Groups of Novel Retroviral Genomes in Pigs and Related Species
Patience, Clive, Switzer, William M., Takeuchi, Yasuhiro, Griffiths, David J., Goward, Melanie E., Heneine, Walid, ...
In view of the concern over potential infection hazards in the use of porcine tissues and organs for xenotransplantation to humans, we investigated the diversity of porcine endogenous retrovirus...
Novel Endogenous Retrovirus in Rabbits Previously Reported as Human Retrovirus 5
Griffiths, David J., Voisset, Cécile, Venables, Patrick J. W., Weiss, Robin A.
Human retrovirus 5 (HRV-5) represented a fragment of a novel retrovirus sequence identified in human RNA and DNA preparations. In this study, the genome of HRV-5 was cloned and sequenced and...
Identification of receptors for pig endogenous retrovirus
Ericsson, Thomas A., Takeuchi, Yasuhiro, Templin, Christian, Quinn, Gary, Farhadian, Shelli F., Wood, James C., ...
Xenotransplantation of porcine tissues has the potential to treat a wide variety of major health problems including organ failure and diabetes. Balanced against the potential benefits of...
Jenner, Richard G., Maillard, Karine, Cattini, Nicola, Weiss, Robin A., Boshoff, Chris, Wooster, Richard, ...
Kaposi's sarcoma-associated herpesvirus is associated with three human tumors: Kaposi's sarcoma, and the B cell lymphomas, plasmablastic lymphoma associated with multicentric Castleman's disease, and...
Proposal for Numbering Mutants of Avian Leukosis and Sarcoma Viruses
Vogt, Peter K., Weiss, Robin A., Hanafusa, Hidesaburo
A system for the numbering of mutants of avian sarcoma and leukosis viruses is proposed.
Detection of Avian Tumor Virus-Specific Nucleotide Sequences in Avian Cell DNAs
Varmus, Harold E., Weiss, Robin A., Friis, Robert R., Levinson, Warren, Bishop, J. Michael
The effect of unlabeled cellular DNA upon the reassociation kinetics of labeled double-stranded DNA made by DNA polymerase from avian tumor viruses has been used to measure virus-specific nucleotide...
Neil, Stuart J. D., Clapham, Paul R., Nibbs, Robert J., McKnight, Áine, Weiss, Robin A.
The role of coreceptors other than CCR5 and CXCR4 in the pathogenesis of human immunodeficiency virus (HIV) disease is controversial. Here we show that a promiscuous CC chemokine receptor, D6, can...
HIV and AIDS in relation to other pandemics
Among the viruses plaguing humans, HIV is a recent acquisition. Its outstanding success as an infection poses immense scientific challenges to human health and raises the question “What comes...
The discovery of endogenous retroviruses
When endogenous retroviruses (ERV) were discovered in the late 1960s, the Mendelian inheritance of retroviral genomes by their hosts was an entirely new concept. Indeed Howard M Temin's DNA provirus...
Dupin, Nicolas, Fisher, Cyril, Kellam, Paul, Ariad, Sam, Tulliez, Micheline, Franck, Nathalie, ...
Human herpesvirus 8 (HHV-8, also called KSHV) is linked to the etiopathogenesis of Kaposi’s sarcoma (KS), multicentric Castleman’s disease (MCD), and primary effusion lymphoma (PEL). The...
Patience, Clive, Takeuchi, Yasuhiro, Cosset, Francois-Loic, Weiss, Robin A.
Interaction of retrovirus vectors and endogenous retroviruses present in packaging cell lines and target cells may result in unwanted events, such as the formation of recombinant viruses and the...
Host Range and Interference Studies of Three Classes of Pig Endogenous Retrovirus
Takeuchi, Yasuhiro, Patience, Clive, Magre, Saema, Weiss, Robin A., Banerjee, Papia T., Le Tissier, Paul, ...
Recent interest in the use of porcine organs, tissues, and cells for xenotransplantation to humans has highlighted the need to characterize the properties of pig endogenous retroviruses (PERVs)....
Virus Load and Sequence Variation in Simian Retrovirus Type 2 Infection
Rosenblum, Lisa L., Weiss, Robin A., McClure, Myra O.
The natural history of type D simian retrovirus (SRV) infection is poorly characterized in terms of viral load, antibody status, and sequence variation. To investigate this, blood samples were taken...
Morozov, Vladimir A., Lagaye, Sylvie, Taylor, Graham P., Matutes, Estella, Weiss, Robin A.
Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia/lymphoma (ATLL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and other diseases....
Kellam, Paul, Bourboulia, Dimitra, Dupin, Nicolas, Shotton, Chris, Fisher, Cyril, Talbot, Simon, ...
Human herpesvirus 8 (HHV-8; also designated Kaposi’s sarcoma-associated herpesvirus) is the likely etiological agent of Kaposi’s sarcoma (KS). HHV-8 encodes a latent nuclear antigen (LNA) which...
Susceptibility of the Porcine Endogenous Retrovirus to Reverse Transcriptase and Protease Inhibitors
Qari, Shoukat H., Magre, Saema, García-Lerma, J. Gerardo, Hussain, Althaf I., Takeuchi, Yasuhiro, Patience, Clive, ...
Porcine xenografts may offer a solution to the shortage of human donor allografts. However, all pigs contain the porcine endogenous retrovirus (PERV), raising concerns regarding the transmission of...
Multiple Groups of Novel Retroviral Genomes in Pigs and Related Species
Patience, Clive, Switzer, William M., Takeuchi, Yasuhiro, Griffiths, David J., Goward, Melanie E., Heneine, Walid, ...
In view of the concern over potential infection hazards in the use of porcine tissues and organs for xenotransplantation to humans, we investigated the diversity of porcine endogenous retrovirus...
Novel Endogenous Retrovirus in Rabbits Previously Reported as Human Retrovirus 5
Griffiths, David J., Voisset, Cécile, Venables, Patrick J. W., Weiss, Robin A.
Human retrovirus 5 (HRV-5) represented a fragment of a novel retrovirus sequence identified in human RNA and DNA preparations. In this study, the genome of HRV-5 was cloned and sequenced and...
Identification of receptors for pig endogenous retrovirus
Ericsson, Thomas A., Takeuchi, Yasuhiro, Templin, Christian, Quinn, Gary, Farhadian, Shelli F., Wood, James C., ...
Xenotransplantation of porcine tissues has the potential to treat a wide variety of major health problems including organ failure and diabetes. Balanced against the potential benefits of...
Jenner, Richard G., Maillard, Karine, Cattini, Nicola, Weiss, Robin A., Boshoff, Chris, Wooster, Richard, ...
Kaposi's sarcoma-associated herpesvirus is associated with three human tumors: Kaposi's sarcoma, and the B cell lymphomas, plasmablastic lymphoma associated with multicentric Castleman's disease, and...
Proposal for Numbering Mutants of Avian Leukosis and Sarcoma Viruses
Vogt, Peter K., Weiss, Robin A., Hanafusa, Hidesaburo
A system for the numbering of mutants of avian sarcoma and leukosis viruses is proposed.
Detection of Avian Tumor Virus-Specific Nucleotide Sequences in Avian Cell DNAs
Varmus, Harold E., Weiss, Robin A., Friis, Robert R., Levinson, Warren, Bishop, J. Michael
The effect of unlabeled cellular DNA upon the reassociation kinetics of labeled double-stranded DNA made by DNA polymerase from avian tumor viruses has been used to measure virus-specific nucleotide...
Neil, Stuart J. D., Clapham, Paul R., Nibbs, Robert J., McKnight, Áine, Weiss, Robin A.
The role of coreceptors other than CCR5 and CXCR4 in the pathogenesis of human immunodeficiency virus (HIV) disease is controversial. Here we show that a promiscuous CC chemokine receptor, D6, can...
HIV and AIDS in relation to other pandemics
Among the viruses plaguing humans, HIV is a recent acquisition. Its outstanding success as an infection poses immense scientific challenges to human health and raises the question “What comes...
The discovery of endogenous retroviruses
When endogenous retroviruses (ERV) were discovered in the late 1960s, the Mendelian inheritance of retroviral genomes by their hosts was an entirely new concept. Indeed Howard M Temin's DNA provirus...
What have we learnt from SARS?
Weiss, Robin A, McLean, Angela R
With outbreaks of infectious disease emerging from animal sources, we have learnt to expect the unexpected. We were, and are, expecting a new influenza A pandemic, but no one predicted the emergence...
Human RNA “Rumor” Viruses: the Search for Novel Human Retroviruses in Chronic Disease
Voisset, Cécile, Weiss, Robin A., Griffiths, David J.
Summary: Retroviruses are an important group of pathogens that cause a variety of diseases in humans and animals. Four human retroviruses are currently known, including human immunodeficiency virus...
Although most epidemic human infectious diseases are caused by recently introduced pathogens, cospeciation of parasite and host is commonplace for endemic infections. Occasional host infidelity,...
Forsman, Anna, Beirnaert, Els, Hoorelbeke, Bart, Hijazi, Karolin, Koh, Willie, ...
Members of the Camelidae family produce immunoglobulins devoid of light chains. We have characterized variable domains of these heavy chain antibodies, the VHH, from llamas immunized with human...
Emerging Technologies for the Detection of Rabies Virus: Challenges and Hopes in the 21st Century
Fooks, Anthony R., Johnson, Nicholas, Freuling, Conrad M., Wakeley, Philip R., Banyard, Ashley C., McElhinney, Lorraine M., ...
The diagnosis of rabies is routinely based on clinical and epidemiological information, especially when exposures are reported in rabies-endemic countries. Diagnostic tests using conventional assays...