Robin Joy Thomson

Synthesis and Biological Evaluation of Galactofuranosyl Alkyl Thioglycosides as Inhibitors of Mycobacteria (2007)

Davis, Christopher, Hartnell, Regan David, Madge, Paul David, Owen, David James, Thomson, Robin Joy, Chong, Andrew, ...

As part of our research interest directed toward the development of antimycobacterial agents, we have investigated compounds based on galactofuranose (Galf), an essential cell wall component of...

Synthesis and Biological Evaluation of Galactofuranosyl Alkyl Thioglycosides as Inhibitors of Mycobacteria (2007)

Davis, Christopher, Hartnell, Regan David, Madge, Paul David, Owen, David James, Thomson, Robin Joy, Chong, Andrew, ...

As part of our research interest directed toward the development of antimycobacterial agents, we have investigated compounds based on galactofuranose (Galf), an essential cell wall component of...

Synthesis and Biological Evaluation of Galactofuranosyl Alkyl Thioglycosides as Inhibitors of Mycobacteria (2007)

Davis, Christopher, Hartnell, Regan David, Madge, Paul David, Owen, David James, Thomson, Robin Joy, Chong, Andrew, ...

As part of our research interest directed toward the development of antimycobacterial agents, we have investigated compounds based on galactofuranose (Galf), an essential cell wall component of...

Synthesis and evaluation of galactofuranosyl N,N-dialkyl sulfenamides and sulfonamides as antimycobacterial agents (2007)

Owen, David James, Davis, Christopher, Hartnell, Regan David, Madge, Paul David, Thomson, Robin Joy, Chong, Andrew, ...

The recent emergence of clinically oppressive superbugs, some with resistance to nearly all frontline drug therapies, has challenged our ability to combat such infectious organisms as Mycobacterium...

Synthesis and evaluation of 4-O-alkylated 2-deoxy-2,3-didehydro-N-acetylneuraminic acid derivatives as inhibitors of human parainfluenza virus type-3 sialidase activity (2007)

Tindal, David James, Dyason, Jeffrey Clifford, Thomson, Robin Joy, Suzuki, Takashi, Ueyama, Hiroo, Kuwahara, Yohta, ...

The X-ray crystal structure of the paramyxoviral surface glycoprotein haemagglutinin-neuraminidase (HN) from Newcastle Disease virus was used as a template to design inhibitors of the HN from human...

Structural analysis of a designed inhibitor complexed with the hemagglutinin-neuraminidase of Newcastle disease virus (2006)

Ryan, Charlotte, Zaitsev, Viateslav, Tindal, David James, Dyason, Jeffrey Clifford, Thomson, Robin Joy, Alymova, Irina, ...

Viruses of the Paramyxoviridae family are the leading cause of respiratory disease in children. The human parainfluenza viruses (hPIV) are members of the Paramyxovirinae subfamily, which also...

Modelling, synthesis and biological evaluation of novel glucoronide-based probes of Vibrio cholerae sialidase (2006)

Mann, Maretta, Thomson, Robin Joy, Dyason, Jeffrey Clifford, McAtamney, Sarah, Von Itzstein, Mark

The development of sialidase inhibitors is an area of continuing interest due to their potential use as therapeutic agents to combat viral and bacterial infections. Herein, we report our studies...

Unsaturated N-acetyl-D-glycosaminuronic acid glycosides as inhibitors of influenza virus sialidase (2006)

Mann, Maretta, Islam, Tasneem, Dyason, Jeffrey Clifford, Florio, Pas, Trower, Carolyn J., Thomson, Robin Joy, ...

The threat of pandemic influenza is a significant concern of governments worldwide. There is a very limited and relatively expensive armament to tackle such a pandemic should it occur. This fact...

An efficient approach to N-acetyl-D-glucosaminuronic acid-based sialylmimetics as potential sialidase inhibitors (2004)

Mann, Maretta, Thomson, Robin Joy, Von Itzstein, Mark

A novel approach to the synthesis of ²-glycosides of N-acetyl-D-glucosaminuronic acid, in six steps and good overall yield from N-acetyl-D-glucosamine, has been developed. The key synthetic step was...

An efficient approach to N-acetyl-D-glucosaminuronic acid-based sialylmimetics as potential sialidase inhibitors (2004)

Mann, Maretta, Thomson, Robin Joy, Von Itzstein, Mark

A novel approach to the synthesis of ²-glycosides of N-acetyl-D-glucosaminuronic acid, in six steps and good overall yield from N-acetyl-D-glucosamine, has been developed. The key synthetic step was...

An efficient approach to N-acetyl-D-glucosaminuronic acid-based sialylmimetics as potential sialidase inhibitors (2004)

Mann, Maretta, Thomson, Robin Joy, Von Itzstein, Mark

A novel approach to the synthesis of ²-glycosides of N-acetyl-D-glucosaminuronic acid, in six steps and good overall yield from N-acetyl-D-glucosamine, has been developed. The key synthetic step was...

An efficient approach to N-acetyl-D-glucosaminuronic acid-based sialylmimetics as potential sialidase inhibitors (2004)

Mann, Maretta, Thomson, Robin Joy, Von Itzstein, Mark

A novel approach to the synthesis of β-glycosides of N-acetyl-D-glucosaminuronic acid, in six steps and good overall yield from N-acetyl-D-glucosamine, has been developed. The key synthetic step was...

Saturation transfer difference (STD) 1H-NMR experiments and in silico docking experiments to probe the binding of N-acetylneuraminic acid and derivatives to Vibrio cholerae sialidase. (2004)

Haselhorst, Thomas Erwin, Wilson, Jenny, Thomson, Robin Joy, McAtamney, Sarah, Menting, John G., Coppel, Ross L., ...

Saturation transfer difference (STD) 1H NMR experiments were used to probe the epitope binding characteristics of the sialidase [EC 3.2.1.18] from the bacterium Vibrio cholerae, the causative agent...

Rapid, clean, and mild O-acetylation of alcohols and carbohydrates in an ionic liquid (2002)

Forsyth, Stewart A, MacFarlane, Douglas R, Thomson, Robin Joy, Von Itzstein, Mark

Archetypal O-acetylation reactions of alcohols and carbohydrates proceed rapidly in high yield under mild conditions in a dicyanamide based ionic liquid, that is not only an effective solvent but...

A convenient synthesis of C-galactofuranosylic compounds (C-galactofuranosides) (2002)

Owen, David J., Thomson, Robin Joy, Von Itzstein, Mark

Galactofuranose sugar units are essential for the production of the cell coat of many pathogenic microorganisms. This sugar is not found in mammals, and so compounds that may interfere with the...

Rapid, clean, and mild O-acetylation of alcohols and carbohydrates in an ionic liquid (2002)

Forsyth, Stewart A, MacFarlane, Douglas R, Thomson, Robin Joy, Von Itzstein, Mark

Archetypal O-acetylation reactions of alcohols and carbohydrates proceed rapidly in high yield under mild conditions in a dicyanamide based ionic liquid, that is not only an effective solvent but...

A convenient synthesis of C-galactofuranosylic compounds (C-galactofuranosides) (2002)

Owen, David J., Thomson, Robin Joy, Von Itzstein, Mark

Galactofuranose sugar units are essential for the production of the cell coat of many pathogenic microorganisms. This sugar is not found in mammals, and so compounds that may interfere with the...

Rapid, clean, and mild O-acetylation of alcohols and carbohydrates in an ionic liquid (2002)

Forsyth, Stewart A, MacFarlane, Douglas R, Thomson, Robin Joy, Von Itzstein, Mark

Archetypal O-acetylation reactions of alcohols and carbohydrates proceed rapidly in high yield under mild conditions in a dicyanamide based ionic liquid, that is not only an effective solvent but...

A convenient synthesis of C-galactofuranosylic compounds (C-galactofuranosides) (2002)

Owen, David J., Thomson, Robin Joy, Von Itzstein, Mark

Galactofuranose sugar units are essential for the production of the cell coat of many pathogenic microorganisms. This sugar is not found in mammals, and so compounds that may interfere with the...

Rapid, clean, and mild O-acetylation of alcohols and carbohydrates in an ionic liquid (2002)

Forsyth, Stewart A, MacFarlane, Douglas R, Thomson, Robin Joy, Von Itzstein, Mark

Archetypal O-acetylation reactions of alcohols and carbohydrates proceed rapidly in high yield under mild conditions in a dicyanamide based ionic liquid, that is not only an effective solvent but...

A convenient synthesis of C-galactofuranosylic compounds (C-galactofuranosides) (2002)

Owen, David J., Thomson, Robin Joy, Von Itzstein, Mark

Galactofuranose sugar units are essential for the production of the cell coat of many pathogenic microorganisms. This sugar is not found in mammals, and so compounds that may interfere with the...

Synthesis of new chiral phosphines for use in catalytic asymmetric reactions (1985)

Thomson, Robin Joy.

Submitted for the degree of Doctor of Philosophy in the Dept. of Chemistry. Summary: leaves xix-xxi. Typescript. Bibliography: leaves 270-284.

Synthesis of new chiral phosphines for use in catalytic asymmetric reactions (1985)

Thomson, Robin Joy.

Submitted for the degree of Doctor of Philosophy in the Dept. of Chemistry. Summary: leaves xix-xxi. Microreproduction of original issued: [Clayton, Vic.] 1985. xxi, 292 leaves (1 folded)....