Ireland, Zoe, Russell, Aaron P, Wallimann, Theo, Walker, David W, Snow, Rod
Abstract Background Creatine synthesis takes place predominately in the kidney and liver via a two-step process involving AGAT ( L -arginine:glycine amidinotransferase) and GAMT (guanidinoacetate...
Ireland, Zoe, Dickinson, Hayley, Snow, Rod, Walker, David W.
Objective We hypothesized that elevating creatine in the maternal diet would reach fetal and placental tissues and improve fetal survival after acute hypoxia at birth.Study DesignPregnant spiny mice...
Murphy, K.T., Aughey, R., Petersen, Aaron, Clark, S., Goodman, Craig, Hawley, John, ...
Aim: This study investigated the effects of endurance training status and sex differences on skeletal muscle Na+,K+-pump mRNA expression, content and activity. Methods: Forty-five endurance-trained...
µ- Calpain and calpain-3 are not autolyzed with exhaustive exercise in humans (2006)
Murphy, Robyn M., Snow, Rod, Lamb, Graham D.
µ-calpain and calpain-3 are Ca2+-dependent proteases found in skeletal muscle. Autolysis of calpains is observed using Western blot analysis as the cleaving of the full-length proteins to...
Sprint training reduces urinary purine loss following intense exercise in humans (2006)
Stathis, Christos G., Carey, Michael F., Hayes, Alan, Garnham, Andrew, Snow, Rod
The influence of allopurinol on urinary purine loss after repeated sprint exercise in man (2005)
Stathis, Christos G., Carey, Michael F., Snow, Rod
The influence of allopurinol on urinary purine loss was examined in 7 active male subjects (age 24.9 ± 3.0 years, weight 82.8 ± 8.3 kg, V˙o2peak 48.1 ± 6.9 mL ·...
Petersen, A. C., Murphy, K. T., Snow, Rod, Leppik, J. A., Aughey, R. J., Garnham, Andrew, ...
We investigated whether depressed muscle Na+-K+-ATPase activity with exercise reflected a loss of Na+-K+-ATPase units, the time course of its recovery postexercise, and whether this depressed...
Murphy, K. Τ., Petersen, A. C., Goodman, C., Gong, X., Leppik, J. Α., Garnham, Anne, ...
This study investigated effects of prolonged submaximal exercise on Na+-K+-ATPase mRNA and protein expression, maximal activity, and content in human skeletal muscle. We also investigated the effects...
Murphy, K., Petersen, A., Goodman, Craig, Gong, X., Leppik, J., Garnham, A., ...
This study investigated effects of prolonged submaximal exercise on Na+-K+-ATPase mRNA and protein expression, maximal activity, and content in human skeletal muscle. We also investigated the effects...
Murphy, K.T., Snow, Rod, Petersen, A., Murphy, R., Mollica, J., Lee, J., ...
Characterization of expression of, and consequently also the acute exercise effects on, Na+,K+-ATPase isoforms in human skeletal muscle remains incomplete and was therefore investigated. Fifteen...
Stephens, T, Canny, B, Snow, Rod, McConell, G
1. The nucleoside intermediate 5'-aminoimidazole-4-carboxyamide-ribonucleoside (AICAR) activates skeletal muscle AMP-activated protein kinase (AMPK) and increases glucose uptake. The AMPK...
Murphy, Robyn M., Tunstall, Rebecca J., Mehan, Kate A., Cameron-Smith, David, McKenna, Michael J., Spriet, Lawrence L., ...
The present study investigated whether there were any differences between males and females in respect to creatine transporter (CreaT) gene expression and/or total creatine (TCr) content in human...
Snow, Rod, Turnbull, J., Da Silva, S., Jiang, F., Tarnopolsky, M. A.
This study investigated the effects of riluzole (Ril), creatine (Cr) and a combination of these treatments on the onset and progression of clinical signs and neuropathology in an animal model of...
Baldwin, Jacinta, Snow, Rod, Gibala, Martin J., Garnham, Andrew, Howarth, Krista, Febbraio, Mark A.
The hypothesis that fatigue during prolonged exercise arises from insufficient intramuscular glycogen, which limits tricarboxylic acid cycle (TCA) activity due to reduced TCA cycle intermediates...
Russell, A., Wadley, G., Hesselink, M., Schaart, G., Lo, Sing Kai, Leger, B., ...
Uncoupling protein 3 (UCP3) is a muscle mitochondrial protein believed to uncouple the respiratory chain, producing heat and reducing aerobic ATP production. Our aim was to quantify and compare the...
Russell, Aaron, Le Rossignol, P., Snow, Rod, Lo, Sing Kai
The accumulated oxygen deficit (AOD) method assumes a linear VO<sub>2</sub>-power relationship for exercise intensities increasing from below the lactate threshold (BLT) to above the...
Reliability of performance in repeated sprint cycling tests (2002)
Watt, K. K. O., Hopkins, W. G., Snow, Rod
We have estimated the reliability of performance in a commonly employed exercise test consisting of repeated sprints on a cycle ergometer. Eight recreationally active young men completed a practice...
Russell, Aaron, Le Rossignol, P., Snow, Rod, Lo, Sing Kai
The aim of the present study was to determine the influence of pedal rate on the precision and quantification of the accumulated oxygen deficit (AOD). Eight trained male triathletes completed a...
Creatine and the creatine transporter: a review (2001)
The cellular role of creatine (Cr) and Cr phosphate (CrP) has been studied extensively in neural, cardiac and skeletal muscle. Several studies have demonstrated that alterations in the cellular total...