Roger A. Johns

Distinct expression of synaptic NR2A and NR2B in the central nervous system and impaired morphine tolerance and physical dependence in mice deficient in postsynaptic density-93 protein (2008)

Liaw, Wen-Jinn, Zhu, Xu-Guang, Yaster, Myron, Johns, Roger A, Gauda, Estelle B, Tao, Yuan-Xiang

Abstract Postsynaptic density (PSD)-93, a neuronal scaffolding protein, binds to and clusters N -methyl-D-aspartate receptor (NMDAR) subunits NR2A and NR2B at cellular membranes in vitro . However,...

PDZ Domains at Excitatory Synapses: Potential Molecular Targets for Persistent Pain Treatment

Tao, Yuan-Xiang, Johns, Roger A

Persistent pain, a common clinical condition, could be caused by inflammation, tissue injury secondary to trauma or surgery, and nerve injuries. It is often inadequately controlled by current...

Distinct expression of synaptic NR2A and NR2B in the central nervous system and impaired morphine tolerance and physical dependence in mice deficient in postsynaptic density-93 protein

Liaw, Wen-Jinn, Zhu, Xu-Guang, Yaster, Myron, Johns, Roger A, Gauda, Estelle B, Tao, Yuan-Xiang

Postsynaptic density (PSD)-93, a neuronal scaffolding protein, binds to and clusters N-methyl-D-aspartate receptor (NMDAR) subunits NR2A and NR2B at cellular membranes in vitro. However, the roles of...