Roland Krüger

138 Genome Informatics 15(1): 138–148 (2004) Model Reduction and Analysis of Robustness for the Wnt/β-Catenin Signal Transduction Pathway (2008)

Roland Krüger, Reinhart Heinrich

We present a framework for model reduction of signal transduction networks. The methods are explained by considering a recent model for Wnt/β-catenin signalling which plays an important regulatory...

Statistical Analysis of the FleetNet Highway Movement Patterns (2005)

Krüger, Roland, Füßler, Holger, Torrent-Moreno, Marc, Transier, Matthias, Hartenstein, Hannes, Effelsberg, Wolfgang

The major objective of the FleetNet project [5, 2] was to develop a platform for inter-vehicle communication based on the principles of ad-hoc communication. In its process, unicast datagram routing...

Studying Vehicle Movements on Highways and their Impact on Ad-Hoc Connectivity (2005)

Füßler, Holger, Torrent-Moreno, Marc, Krüger, Roland, Transier, Matthias, Hartenstein, Hannes, Effelsberg, Wolfgang

While Mobile Ad-Hoc Networks are generally studied using a randomized node move- ment model such as the Random Way-Point model [8], Vehicular Ad-Hoc Networks deal with street-bound vehicles following...

Integrative model of the response of yeast to osmotic shock (2005)

Klipp, Edda, Nordlander, Bodil, Krüger, Roland, Gennemark, Peter, Hohmann, Stefan

Integration of experimental studies with mathematical modeling allows insight into systems properties, prediction of perturbation effects and generation of hypotheses for further research. We present...

Studying Vehicle Movements on Highways and their Impact on Ad-Hoc Connectivity (2005)

Holger Füßler, Roland Krüger, Marc Torrent-moreno, Hannes Hartenstein

➔ Ad-hoc routing research is mainly based on node mobility models like Random Way-Point (RWP). ➔ RWP is used as a 'general'/average movement model and is well-understood analytically....

The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway (2003)

Ethan Lee, Adrian Salic, Roland Krüger, Reinhart Heinrich, Marc W. Kirschner

Wnt signaling is important in both oncogenesis and development. Mathematical modeling predicts several unusual features of the Wnt pathway, some of which are tested experimentally.

The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway (2003)

Ethan Lee, Adrian Salic, Roland Krüger, Reinhart Heinrich, Marc W. Kirschner

Wnt signaling plays an important role in both oncogenesis and development. Activation of the Wnt pathway results in stabilization of the transcriptional coactivator β-catenin. Recent studies have...

The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway

Lee, Ethan, Salic, Adrian, Krüger, Roland, Heinrich, Reinhart, Kirschner, Marc W

Wnt signaling plays an important role in both oncogenesis and development. Activation of the Wnt pathway results in stabilization of the transcriptional coactivator β-catenin. Recent studies have...

The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway

Lee, Ethan, Salic, Adrian, Krüger, Roland, Heinrich, Reinhart, Kirschner, Marc W

Wnt signaling plays an important role in both oncogenesis and development. Activation of the Wnt pathway results in stabilization of the transcriptional coactivator β-catenin. Recent studies have...