Ron D. M. Soede

Phosphorylation of Chemoattractant Receptors Is Not Essential for Chemotaxis or Termination of G-protein-mediated Responses (1997)

Kim, Ji-Yun, Soede, Ron D.M., Schaap, Pauline, Valkema, Romi, Borleis, Jane A., Haastert, Peter J.M. Van, ...

In several G-protein-coupled signaling systems, ligand-induced receptor phosphorylation by specific kinases is suggested to lead to desensitization via mechanisms including receptor/G-protein...

Cell-permeable Non-hydrolyzable cAMP Derivatives as Tools for Analysis of Signaling Pathways Controlling Gene Regulation in Dictyostelium (1993)

Schaap, Pauline, Ments-Cohen, Martine Van, Soede, Ron D.M., Brandt, Raymond, Firtel, Richard A., Dostmann, Wolfgang, ...

A novel class of cAMP derivatives were tested for binding to surface cAMP receptors (CAR), protein kinase A (PKA), and cAMP-phosphodiesterase (PDE) and for induction of three classes of cAMP...

ZAP-70 Tyrosine Kinase Is Required for LFA-1–dependent T Cell Migration

Soede, Ron D.M., Wijnands, Yvonne M., Van Kouteren-Cobzaru, Ioana, Roos, Ed

The ZAP-70 tyrosine kinase is essential for T cell activation by the T cell receptor. We show that ZAP-70 is also required for migration of T cells that is dependent on the integrin LFA-1. Invasion...