Hovatta, Iiris, Zapala, Matthew A, Broide, Ron S, Schadt, Eric E, Libiger, Ondrej, Schork, Nicholas J, ...
Abstract Background Expression quantitative trait locus (eQTL) mapping is used to find loci that are responsible for the transcriptional activity of a particular gene. In recent eQTL studies,...
Adult mouse brain gene expression patterns bear an embryologic imprint
Zapala, Matthew A., Hovatta, Iiris, Ellison, Julie A., Wodicka, Lisa, Del Rio, Jo A., Tennant, Richard, ...
The current model to explain the organization of the mammalian nervous system is based on studies of anatomy, embryology, and evolution. To further investigate the molecular organization of the adult...
Adult mouse brain gene expression patterns bear an embryologic imprint
Zapala, Matthew A., Hovatta, Iiris, Ellison, Julie A., Wodicka, Lisa, Del Rio, Jo A., Tennant, Richard, ...
The current model to explain the organization of the mammalian nervous system is based on studies of anatomy, embryology, and evolution. To further investigate the molecular organization of the adult...
Hovatta, Iiris, Zapala, Matthew A, Broide, Ron S, Schadt, Eric E, Libiger, Ondrej, Schork, Nicholas J, ...
Gene expression profiles of five brain regions from six inbred mouse strains suggest that many regulatory networks are highly specific to particular brain regions.
Nootropic α7 nicotinic receptor allosteric modulator derived from GABAA receptor modulators
Ng, Herman J., Whittemore, Edward R., Tran, Minhtam B., Hogenkamp, Derk J., Broide, Ron S., Johnstone, Timothy B., ...
Activation of brain α7 nicotinic acetylcholine receptors (α7 nAChRs) has broad therapeutic potential in CNS diseases related to cognitive dysfunction, including Alzheimer's disease and...