Ronald J. Ellis

Genetic attributes of cerebrospinal fluid-derived HIV-1 env (2006)

Pillai, Satish K., Pond, Sergei L. Kosakovsky, Liu, Yang, Good, Benjamin M., Strain, Matthew C., Ellis, Ronald J., ...

HIV-1 often invades the CNS during primary infection, eventually resulting in neurological disorders in up to 50% of untreated patients. The CNS is a distinct viral reservoir, differing from...

Genetic attributes of cerebrospinal fluid-derived HIV-1 env (2006)

Pillai, Satish K., Kosakovsky Pond, Sergei L., Liu, Yang, Good, Benjamin M., Strain, Matthew C., Ellis, Ronald J., ...

HIV-1 often invades the CNS during primary infection, eventually resulting in neurological disorders in up to 50% of untreated patients. The CNS is a distinct viral reservoir, differing from...

Elevated cerebrospinal fluid quinolinic acid levels are associated with region-specific cerebral volume loss in HIV infection (2001)

Heyes, Melvyn P., Ellis, Ronald J., Ryan, Lee, Childers, Meredith E., Grant, Igor, Wolfson, Tanya, ...

Neuronal injury, dendritic loss and brain atrophy are frequent complications of infection with human immunodeficiency virus (HIV) type 1. Activated brain macrophages and microglia can release...

Indinavir Population Pharmacokinetics in Plasma and Cerebrospinal Fluid

Letendre, Scott L., Capparelli, Edmund V., Ellis, Ronald J., McCutchan, J. Allen

Plasma and cerebrospinal fluid (CSF) indinavir concentrations were measured by high-performance liquid chromatography. The median concentration in plasma exceeded that in CSF 10-fold. The modeled CSF...

Population Pharmacokinetics of Abacavir in Plasma and Cerebrospinal Fluid

Capparelli, Edmund V., Letendre, Scott L., Ellis, Ronald J., Patel, Parul, Holland, Diane, McCutchan, J. Allen

The distribution of abacavir into the cerebrospinal fluid (CSF) was assessed by use of a population pharmacokinetic analysis. Plasma and CSF abacavir concentrations in 54 subjects were determined....

Indinavir Population Pharmacokinetics in Plasma and Cerebrospinal Fluid

Letendre, Scott L., Capparelli, Edmund V., Ellis, Ronald J., McCutchan, J. Allen

Plasma and cerebrospinal fluid (CSF) indinavir concentrations were measured by high-performance liquid chromatography. The median concentration in plasma exceeded that in CSF 10-fold. The modeled CSF...

Population Pharmacokinetics of Abacavir in Plasma and Cerebrospinal Fluid

Capparelli, Edmund V., Letendre, Scott L., Ellis, Ronald J., Patel, Parul, Holland, Diane, McCutchan, J. Allen

The distribution of abacavir into the cerebrospinal fluid (CSF) was assessed by use of a population pharmacokinetic analysis. Plasma and CSF abacavir concentrations in 54 subjects were determined....

HIV Infection and the Central Nervous System: A Primer

Ellis, Ronald J., Calero, Patricia, Stockin, Michael D.

The purpose of this brief review is to prepare readers who may be unfamiliar with Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) and the rapidly accumulating changes in...