Ronald J. Lukas

Functional presynaptic [alpha]6-containing nicotinic acetylcholine receptors participate in nicotine reward in the VTA: where and how (2009)

Kechun Yang, Lori Buhlman, Ming Gao, Ghous M. Khan, Robert A. Nichols, Jamie DeChon, ...

In the ventral tegmental area (VTA), [alpha]6-nAChRs express abundantly, but their location, function, pharmacology, and roles in cholinergic modulation of dopaminergic (DA) neurons remain elusive....

Roles of nicotinic acetylcholine receptor beta subunits in function of human alpha4-containing nicotinic receptors (2006)

Yu, Kewei, Hu, Jun, Kuo, Yen-Ping, Segerberg, Marsha, ...

Naturally expressed nicotinic acetylcholine receptors (nAChR) containing alpha4 subunits (alpha4*-nAChR) in combination with beta2 subunits (alpha4beta2-nAChR) are among the most abundant,...

Mol Pharmacol 66:675–682, 2004 Printed in U.S.A. Enantioselective Effects of Hydroxy Metabolites of Bupropion on Behavior and on Function of Monoamine Transporters and (2004)

Nicotinic Receptors, M. Imad Damaj, F. Ivy Carroll, J. Brek Eaton, Hernan A. Navarro, Bruce E. Blough, ...

Bupropion is an atypical antidepressant that also has usefulness as a smoking-cessation aid. Because hydroxybupropion, a major metabolite of bupropion, is believed to contribute to its antidepressant...

Roles of nicotinic acetylcholine receptor β subunits in function of human α4-containing nicotinic receptors

Wu, Jie, Liu, Qiang, Yu, Kewei, Hu, Jun, Kuo, Yen-Ping, Segerberg, Marsha, ...

Naturally expressed nicotinic acetylcholine receptors (nAChR) containing α4 subunits (α4*-nAChR) in combination with β2 subunits (α4β2-nAChR) are among the most abundant, high-affinity nicotine...

Evaluation of benzyltetrahydroisoquinolines as ligands for neuronal nicotinic acetylcholine receptors

Exley, Richard, Iturriaga-Vásquez, Patricio, Lukas, Ronald J, Sher, Emanuele, Cassels, Bruce K, Bermudez, Isabel

Effects of derivatives of coclaurine (C), which mimic the ‘eastern' or the nonquaternary halves of the alkaloids tetrandrine or d-tubocurarine, respectively, both of which are inhibitors of...