Ronda K. Sapp

A functional SNP of interferon-γ gene is important for interferon-α-induced and spontaneous recovery from hepatitis C virus infection

Huang, Ying, Yang, Huiying, Borg, Brian B., Su, Xiaowen, Rhodes, Shannon L., Yang, Kai, ...

Cytokine polymorphisms are associated with disease outcome and interferon (IFN) treatment response in hepatitis C virus (HCV) infection. We genotyped eight SNPs spanning the entire IFN-γ gene in two...

Production of Infectious Hepatitis C Virus of Various Genotypes in Cell Cultures▿

Kato, Takanobu, Matsumura, Takuya, Heller, Theo, Saito, Satoru, Sapp, Ronda K., Murthy, Krishna, ...

A unique hepatitis C virus (HCV) strain JFH-1 has been shown to replicate efficiently in cell culture with production of infectious HCV. We previously developed a DNA expression system containing HCV...

Immunization with hepatitis C virus-like particles results in control of hepatitis C virus infection in chimpanzees

Elmowalid, Gamal A., Qiao, Ming, Jeong, Sook-Hyang, Borg, Brian B., Baumert, Thomas F., Sapp, Ronda K., ...

Recombinant hepatitis C virus (HCV)-like particles (HCV-LPs) containing HCV structural proteins (core, E1, and E2) produced in insect cells resemble the putative HCV virions and are capable of...