Rong Wu

Novel Candidate Targets of �-Catenin/T-cell Factor Signaling Identified by Gene Expression Profiling of Ovarian Endometrioid Adenocarcinomas 1 (2008)

Donald R. Schwartz, Rong Wu, Albert M. Levin, Chiang-ching Huang, Kerby A. Shedden, ...

The activity of �-catenin (�-cat), a key component of the Wnt signaling pathway, is deregulated in about 40 % of ovarian endometrioid adenocarcinomas (OEAs), usually as a result of CTNNB1 gene...

Scalable scheduling of parallel servers (2007)

Wu, Rong

With the increasing use of distributed systems, designing effective task scheduling policies becomes increasingly crucial. We study scheduling for tightly coupled server systems (a single queue for...

Controllability of open quantum systems with Kraus-map dynamics (2006)

Wu, Rong, Pechen, Alexander, Brif, Constantin, Rabitz, Herschel

This paper presents a constructive proof of complete kinematic state controllability of finite-dimensional open quantum systems whose dynamics are represented by Kraus maps. For any pair of states...

Multi-layered round robin routing for parallel servers (2004)

Douglas G. Down, Rong Wu

(Work done while both authors were visitors at EURANDOM, P.O. Box 513,

B.: SCENATOR: a prototype tool for requirements inconsistency detection (2003)

Rong Wu

Based on very elementary mathematical concepts, SCENATOR allows a short feed-back cycle between stakeholders and specifiers. It also scales up the size of formal software requirements which can be...

Total duration of negative surplus for the compound Poisson process that is perturbed by diffusion (2002)

Zhang, Chunsheng, Wu, Rong

In this paper, we consider the compound Poisson process that is perturbed by diffusion (CPD). We derive formulae for the Laplace transform, expectation and variance of total duration of negative...

Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals (2002)

Cowell,Ian G., Aucott,Rebecca, Mahadevaiah,Shantha K., Burgoyne,Paul S., Huskisson,Neville, Bongiorni,Silvia, ...

We show that methylated lysine 9 of histone H3 (Me9H3) is a marker of heterochromatin in divergent animal species. It localises to both constitutive and facultative heterochromatin and replicates...

Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals (2002)

Cowell, Ian G., Aucott, Rebecca, Mahadevaiah, Shantha K., Burgoyne, Paul S., Huskisson, Neville, Bongiorni, Silvia, ...

We show that methylated lysine 9 of histone H3 (Me9H3) is a marker of heterochromatin in divergent animal species. It localises to both constitutive and facultative heterochromatin and replicates...

Neurotoxic Activity of the HIV-1 Envelope Glycoprotein: Activation of Protein Kinase C in Rat Astrocytes (2002)

Oyewole Adeyemo, Rong Wu, Scott Parker, Etty N. Benveniste, Eric Hunter, Isaac Adebayo

Abstract: Envelope glycoprotein (gp120) of the human immunodeficiency virus type one (HIV-1), has adverse effects on glial cells and neurons. This study reports on the direct effect of recombinant...

Transaction Management for a Main-Memory Database (2002)

Piyush Burte, Boanerges Aleman-meza, D. Brent Weatherly, Rong Wu, Supervising Professor, John A. Miller

As part of research by members of the Department of Computer Science at the University of Georgia, we have developed a Java-based Transaction Manager that fits into the multi-layered design of MMODB,...

Empirical evidence that algorithm animation promoted understand of distributed algorithms (2002)

Mihail E. Tudoreanu, Rong Wu, Ashley Hamilton-taylor, Eileen Kraemer

Previous studies of program visualization have generally failed to provide convincing support for the benefits of algorithm animation in promoting the understanding of computations. This paper...

Algorithm Animation Beneficial in Understanding Distributed Algorithms (2002)

Mihail E. Tudoreanu, Rong Wu, Ashley Hamilton-Taylor, Eileen Kraemer

Previous studies of program visualization have failed to provide convincing support for the benefits of algorithm animation in promoting the understanding of computations. This paper presents a study...

Restored Expression of Fragile Histidine Triad Protein and Tumorigenicity of Cervical Carcinoma Cells (2000)

Wu, Rong, Connolly, Denise C., Dunn, Rodney L., Cho, Kathleen R.

BACKGROUND: Allelic losses in the short arm of chromosome 3 are common in cervical carcinomas. The fragile histidine triad (FHIT) gene at chromosome region 3p14.2 is a candidate tumor suppressor gene...

Increased p50/p50 NF-κB Activation in Human Papillomavirus Type 6- or Type 11-Induced Laryngeal Papilloma Tissue

Vancurova, Ivana, Wu, Rong, Miskolci, Veronika, Sun, Shishinn

We have observed elevated NF-κB DNA-binding activity in nuclear extracts from human papillomavirus type 6- and 11-infected laryngeal papilloma tissues. The predominant DNA-binding species is the...

Differential Subnuclear Localization and Replication Timing of Histone H3 Lysine 9 Methylation States

Wu, Rong, Terry, Anna V., Singh, Prim B., Gilbert, David M.

Mono-, di-, and trimethylation of specific histone residues adds an additional level of complexity to the range of histone modifications that may contribute to a histone code. However, it has not...

Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing

Feijoo, Carmen, Hall-Jackson, Clare, Wu, Rong, Jenkins, David, Leitch, Jane, Gilbert, David M., ...

Checkpoints maintain order and fidelity in the cell cycle by blocking late-occurring events when earlier events are improperly executed. Here we describe evidence for the participation of Chk1 in an...

Requirement of STAT3 Activation for Differentiation of Mucosal Stratified Squamous Epithelium

Wu, Rong, Sun, Shishinn, Steinberg, Bettie M

STAT3, a member of the signal transducers and activators of transcription (STAT) family, has been shown to play a key role in promoting proliferation, differentiation, or cell cycle progression,...

Somatic Mutations of the PPP2R1B Candidate Tumor Suppressor Gene at Chromosome 11q23 are Infrequent in Ovarian Carcinomas

Wu, Rong, Connolly, Denise C, Ren, Xiaodan, Fearon, Eric R, Cho, Kathleen R

Previous studies have demonstrated frequent allelic losses of distal chromosome 11q in ovarian carcinomas. The tumor suppressor gene(s) presumably targeted by these losses have not yet been...

Increased p50/p50 NF-κB Activation in Human Papillomavirus Type 6- or Type 11-Induced Laryngeal Papilloma Tissue

Vancurova, Ivana, Wu, Rong, Miskolci, Veronika, Sun, Shishinn

We have observed elevated NF-κB DNA-binding activity in nuclear extracts from human papillomavirus type 6- and 11-infected laryngeal papilloma tissues. The predominant DNA-binding species is the...

Differential Subnuclear Localization and Replication Timing of Histone H3 Lysine 9 Methylation States

Wu, Rong, Terry, Anna V., Singh, Prim B., Gilbert, David M.

Mono-, di-, and trimethylation of specific histone residues adds an additional level of complexity to the range of histone modifications that may contribute to a histone code. However, it has not...

Requirement of STAT3 Activation for Differentiation of Mucosal Stratified Squamous Epithelium

Wu, Rong, Sun, Shishinn, Steinberg, Bettie M

STAT3, a member of the signal transducers and activators of transcription (STAT) family, has been shown to play a key role in promoting proliferation, differentiation, or cell cycle progression,...

Somatic Mutations of the PPP2R1B Candidate Tumor Suppressor Gene at Chromosome 11q23 are Infrequent in Ovarian Carcinomas

Wu, Rong, Connolly, Denise C, Ren, Xiaodan, Fearon, Eric R, Cho, Kathleen R

Previous studies have demonstrated frequent allelic losses of distal chromosome 11q in ovarian carcinomas. The tumor suppressor gene(s) presumably targeted by these losses have not yet been...

Molecular Genetic Evidence Supporting the Clonality and Appendiceal Origin of Pseudomyxoma Peritonei in Women

Szych, Christine, Staebler, Annette, Connolly, Denise C., Wu, Rong, Cho, Kathleen R., Ronnett, Brigitte M.

Pseudomyxoma peritonei (PMP) is a poorly understood condition characterized by mucinous ascites and multifocal peritoneal mucinous tumors. Women with PMP often have mucinous tumors involving both the...

Amplification and Overexpression of the L-MYC Proto-Oncogene in Ovarian Carcinomas

Wu, Rong, Lin, Lin, Beer, David G., Ellenson, Lora H., Lamb, Barbara J., Rouillard, Jean-Marie, ...

Gene amplification is an important mechanism of oncogene activation in various human cancers, including ovarian carcinomas (OvCas). We used restriction landmark genomic scanning (RLGS) to detect...

Role of β-Catenin/T-Cell Factor-Regulated Genes in Ovarian Endometrioid Adenocarcinomas

Zhai, Yali, Wu, Rong, Schwartz, Donald R., Darrah, Danielle, Reed, Heather, Kolligs, Frank T., ...

In various cancers, inactivating mutations in the adenomatous polyposis coli or Axin tumor suppressor proteins or activating mutations in β-catenin’s amino-terminal domain elevate β-catenin...

Up-regulation of Rac1 by Epidermal Growth Factor Mediates COX-2 Expression in Recurrent Respiratory Papillomas

Wu, Rong, Coniglio, Salvatore J, Chan, Amanda, Symons, Marc H, Steinberg, Bettie M

Recurrent respiratory papillomas are epithelial tumors of the airway caused by human papillomaviruses. We previously reported that the epidermal growth factor receptor (EGFR) is overexpressed in...

Classifications of ovarian cancer tissues by proteomic patterns

Zhu, Yi, Wu, Rong, Sangha, Navneet, Yoo, Chul, Cho, Kathleen R., Shedden, Kerby A., ...

Ovarian cancer is a morphologically and biologically heterogeneous disease. The identification of type-specific protein markers for ovarian cancer would provide the basis for more tailored...

Uncoupling global and fine-tuning replication timing determinants for mouse pericentric heterochromatin

Wu, Rong, Singh, Prim B., Gilbert, David M.

Mouse chromocenters are clusters of late-replicating pericentric heterochromatin containing HP1 bound to trimethylated lysine 9 of histone H3 (Me3K9H3). Using a cell-free system to initiate...

Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing

Feijoo, Carmen, Hall-Jackson, Clare, Wu, Rong, Jenkins, David, Leitch, Jane, Gilbert, David M., ...

Checkpoints maintain order and fidelity in the cell cycle by blocking late-occurring events when earlier events are improperly executed. Here we describe evidence for the participation of Chk1 in an...

Immune Dysregulation and Tumor-Associated Gene Changes in Recurrent Respiratory Papillomatosis: A Paired Microarray Analysis

DeVoti, James A, Rosenthal, David W, Wu, Rong, Abramson, Allan L, Steinberg, Bettie M, Bonagura, Vincent R

Recurrent respiratory papillomas (RRP) are benign airway tumors, caused primarily by human papillomaviruses (HPV) types 6 and 11. The disease is characterized by multiple recurrences after surgical...

The expected discounted penalty function for the perturbed compound Poisson risk process with constant interest

Wang, Guojing, Wu, Rong

In this paper, we consider the Gerber-Shiu expected discounted penalty function for the perturbed compound Poisson risk process with constant force of interest. We decompose the Gerber-Shiu function...

Neurofibromin 1 (NF1) Defects Are Common in Human Ovarian Serous Carcinomas and Co-occur with TP53 Mutations12

Sangha, Navneet, Wu, Rong, Kuick, Rork, Powers, Scott, Mu, David, Fiander, Diane, ...

Ovarian serous carcinoma (OSC) is the most common and lethal histologic type of ovarian epithelial malignancy. Mutations of TP53 and dysfunction of the Brca1 and/or Brca2 tumor-suppressor proteins...

The distribution of the first [beta] point in the classical risk model with interest

Li, Zhigang, Wu, Rong, Du, Yonghong

In this paper we investigate the distribution function and the Laplace-Stieltjes Transform(L-S-T) of the first [beta] point of the surplus process {U(t),t[greater-or-equal, slanted]0} using its...

Round robin scheduling of heterogeneous parallel servers in heavy traffic

Wu, Rong, Down, Douglas G.

We consider scheduling for heterogeneous server systems, where tasks arrive according to a Poisson process, with their processing requirements following a discrete distribution with finite support....

Total duration of negative surplus for the risk model with debit interest

He, Jingmin, Wu, Rong, Zhang, Huayue

This paper investigates the compound Poisson risk model with debit interest. The model assumes that the company is allowed to borrow at some debit interest rate when the surplus turns negative. We...