Ovarian Cancer Pathogenesis: A Model in Evolution (2010)
Alison M. Karst, Ronny Drapkin
Ovarian cancer is a deadly disease for which there is no effective means of early detection. Ovarian carcinomas comprise a diverse group of neoplasms, exhibiting a wide range of morphological...
Ovarian Cancer Pathogenesis: A Model in Evolution (2010)
Alison M. Karst, Ronny Drapkin
Ovarian cancer is a deadly disease for which there is no effective means of early detection. Ovarian carcinomas comprise a diverse group of neoplasms, exhibiting a wide range of morphological...
Kanellopoulou, Chryssa, Muljo, Stefan A., Kung, Andrew L., Ganesan, Shridar, Drapkin, Ronny, Jenuwein, Thomas, ...
Dicer is the enzyme that cleaves double-stranded RNA (dsRNA) into 21–25-nt-long species responsible for sequence-specific RNA-induced gene silencing at the transcriptional, post-transcriptional, or...
Cantor, Sharon B., Drapkin, Ronny, Zhang, Fan, Lin, Yafang, Han, Juliana, Pamidi, Sushmita, ...
BACH1 is a nuclear protein that directly interacts with the highly conserved, C-terminal BRCT repeats of the tumor suppressor, BRCA1. Mutations within the BRCT repeats disrupt the interaction between...
Cantor, Sharon B., Bell, Daphne W., Ganesan, Shridar, Kass, Elizabeth M., Drapkin, Ronny, Grossman, Steven R., ...
BRCA1 interacts in vivo with a novel protein, BACH1, a member of the DEAH helicase family. BACH1 binds directly to the BRCT repeats of BRCA1. A BACH1 derivative, bearing a mutation in a residue that...
Cantor, Sharon, Drapkin, Ronny, Zhang, Fan, Lin, Yafang, Han, Juliana, Pamidi, Sushmita, ...
BACH1 is a nuclear protein that directly interacts with the highly conserved, C-terminal BRCT repeats of the tumor suppressor, BRCA1. Mutations within the BRCT repeats disrupt the interaction between...
Kanellopoulou, Chryssa, Muljo, Stefan A., Kung, Andrew L., Ganesan, Shridar, Drapkin, Ronny, Jenuwein, Thomas, ...
Dicer is the enzyme that cleaves double-stranded RNA (dsRNA) into 21–25-nt-long species responsible for sequence-specific RNA-induced gene silencing at the transcriptional, post-transcriptional, or...
Cantor, Sharon, Drapkin, Ronny, Zhang, Fan, Lin, Yafang, Han, Juliana, Pamidi, Sushmita, ...
BACH1 is a nuclear protein that directly interacts with the highly conserved, C-terminal BRCT repeats of the tumor suppressor, BRCA1. Mutations within the BRCT repeats disrupt the interaction between...
Kanellopoulou, Chryssa, Muljo, Stefan A., Kung, Andrew L., Ganesan, Shridar, Drapkin, Ronny, Jenuwein, Thomas, ...
Dicer is the enzyme that cleaves double-stranded RNA (dsRNA) into 21–25-nt-long species responsible for sequence-specific RNA-induced gene silencing at the transcriptional, post-transcriptional, or...
Association of BRCA1 with the inactive X chromosome and XIST RNA.
Ganesan, Shridar, Silver, Daniel P, Drapkin, Ronny, Greenberg, Roger, Feunteun, Jean, Livingston, David M
Breast cancer, early onset 1 (BRCA1) encodes a nuclear protein that participates in breast and ovarian cancer suppression. The molecular basis for the gender and tissue specificity of the BRCA1...
Lessons from BRCA: The Tubal Fimbria Emerges as an Origin for Pelvic Serous Cancer
Crum, Christopher P., Drapkin, Ronny, Kindelberger, David, Medeiros, Fabiola, Miron, Alexander, Lee, Yonghee
Ovarian epithelial cancer is diagnosed in approximately 25,000 women yearly in the United States, accounting for approximately 12,500 deaths. Of these tumors, serous cancer is the most lethal, due to...
Ovarian Cancer Pathogenesis: A Model in Evolution
Karst, Alison M., Drapkin, Ronny
Ovarian cancer is a deadly disease for which there is no effective means of early detection. Ovarian carcinomas comprise a diverse group of neoplasms, exhibiting a wide range of morphological...
New Insights Into the Pathogenesis of Serous Ovarian Cancer and Its Clinical Impact
Levanon, Keren, Crum, Christopher, Drapkin, Ronny
There are only a handful of concepts concerning cancer and carcinogenesis that are currently beyond dispute. One such dogma is the adenoma-carcinoma sequence and that a multistep accumulation of...