Screening fetal losses for monosomy X with a simple PCR-based procedure (2000)
Pereira,Rinaldo W., Sturzeneker,Rosane, Pena,Sérgio D.J.
To screen for monosomy X in spontaneous fetal losses we explored a simple molecular strategy based on loss of heterozygosity at highly polymorphic X-linked loci. We developed a multiplex fluorescent...
Sturzeneker, Rosane, Bevilacqua, Roberta A.U., Haddad, Luciana A., Simpson, Andrew J.G., Pena, Sérgio D.J.
We screened 42 sporadic gastric tumors and found that seven of them had significant microsatellite instability. These were then studied at 26 microsatellite loci, comprising di-, tri- and...
Diagnosis of the fragile X syndrome in males using methylation-specific PCR of the FMRI locus (1999)
Pena,Sérgio D.J., Sturzeneker,Rosane
We have developed a non-isotopic technique based on methylation-specific PCR (MSP) of the FMR1 promoter for the identification of fragile X full mutations among men. DNA samples were first treated...