Combinatorial roles for pRB, p107, and p130 in E2F-mediated cell cycle control
Classon, Marie, Salama, Sofie, Gorka, Carolyn, Mulloy, Roseann, Braun, Pascal, Harlow, Ed
Numerous studies have implicated the pRB family of nuclear proteins in the control of cell cycle progression. Although over-expression experiments have revealed that each of these proteins, pRB,...
Opposing roles of pRB and p107 in adipocyte differentiation
Classon, Marie, Kennedy, Brian K., Mulloy, Roseann, Harlow, Ed
The retinoblastoma (RB) family of proteins, pRB, p107, and p130, have been postulated to be partially redundant in their ability to regulate progression through the G1 phase of the cell cycle....
The Retinoblastoma Protein Is Required for Ras-Induced Oncogenic Transformation†
Williams, Jonathan P., Stewart, Timothy, Li, Bihua, Mulloy, Roseann, Dimova, Dessislava, Classon, Marie
Most human cancers involve either mutational activation of the Ras oncogenic pathway and/or inactivation of the retinoblastoma tumor suppressor (RB) pathway. Paradoxically, tumors that harbor Ras...
Combinatorial roles for pRB, p107, and p130 in E2F-mediated cell cycle control
Classon, Marie, Salama, Sofie, Gorka, Carolyn, Mulloy, Roseann, Braun, Pascal, Harlow, Ed
Numerous studies have implicated the pRB family of nuclear proteins in the control of cell cycle progression. Although over-expression experiments have revealed that each of these proteins, pRB,...
Opposing roles of pRB and p107 in adipocyte differentiation
Classon, Marie, Kennedy, Brian K., Mulloy, Roseann, Harlow, Ed
The retinoblastoma (RB) family of proteins, pRB, p107, and p130, have been postulated to be partially redundant in their ability to regulate progression through the G1 phase of the cell cycle....
The Retinoblastoma Protein Is Required for Ras-Induced Oncogenic Transformation†
Williams, Jonathan P., Stewart, Timothy, Li, Bihua, Mulloy, Roseann, Dimova, Dessislava, Classon, Marie
Most human cancers involve either mutational activation of the Ras oncogenic pathway and/or inactivation of the retinoblastoma tumor suppressor (RB) pathway. Paradoxically, tumors that harbor Ras...
p190A RhoGAP Is a Glycogen Synthase Kinase-3-β Substrate Required for Polarized Cell Migration*S⃞
Jiang, Wei, Betson, Martha, Mulloy, Roseann, Foster, Rosemary, Lévay, Magdolna, Ligeti, Erzsébet, ...
The Rho GTPases are critical regulators of the actin cytoskeleton and are required for cell adhesion, migration, and polarity. Among the key Rho regulatory proteins in the context of cell migration...