Forest Baskett, Tom Jermoluk, James Boyle, Ralph Butler, Terrence Disz, Barnett Glick-feld, ...
arithmetic instructions executed. If successful, these algorithmsmay cause us to reexamine the issues of cache contents and interframe temporal locality in greater detail.
FIGfams: yet another set of protein families (2009)
Meyer, Folker, Overbeek, Ross, Rodriguez, Alex
We present FIGfams, a new collection of over 100 000 protein families that are the product of manual curation and close strain comparison. Using the Subsystem approach the manual curation is carried...
Forest Baskett, Tom Jermoluk, James Boyle, Ralph Butler, Terrence Disz, Barnett Glick-feld, ...
arithmetic instructions executed. If successful, these algorithmsmay cause us to reexamine the issues of cache contents and interframe temporal locality in greater detail.
Evgeni Selkov, Terry Gaasterland, Igor Goryanin, Yuri Gretchkin, Natalia Maltsev, Valeri Nenashev, ...
y
McNeil, Leslie Klis, Reich, Claudia, Aziz, Ramy K., Bartels, Daniela, Cohoon, Matthew, Disz, Terry, ...
The National Microbial Pathogen Data Resource (NMPDR) (http://www.nmpdr.org) is a National Institute of Allergy and Infections Disease (NIAID)-funded Bioinformatics Resource Center that supports...
Insights into social insects from the genome of the honeybee Apis mellifera (2006)
Robinson, Gene E, Gibbs, Richard A, Worley, Kim C, Evans, Jay D, Maleszka, Ryszard, ...
Here we report the genome sequence of the honeybee Apis mellifera, a key model for social behaviour and essential to global ecology through pollination. Compared with other sequenced insect genomes,...
McNeil, Leslie Klis, Reich, Claudia, Aziz, Ramy K., Bartels, Daniela, Cohoon, Matthew, Disz, Terry, ...
The National Microbial Pathogen Data Resource (NMPDR) (http://www.nmpdr.org) is a National Institute of Allergy and Infections Disease (NIAID)-funded Bioinformatics Resource Center that supports...
McNeil, Leslie Klis, Reich, Claudia, Aziz, Ramy K., Bartels, Daniela, Cohoon, Matthew, Disz, Terry, ...
The National Microbial Pathogen Data Resource (NMPDR) (http://www.nmpdr.org) is a National Institute of Allergy and Infections Disease (NIAID)-funded Bioinformatics Resource Center that supports...
Comparative genome analysis of Bacillus cereus group genomes with Bacillus subtilis (2005)
Anderson, Iain, Sorokin, Alexei, Kapatral, Vinayak, Reznik, Gary, Bhattacharya, Anamitra, Mikhailova, Natalia, ...
Genome features of the Bacillus cereus group genomes (representative strains of Bacillus cereus, Bacillus anthracis and Bacillus thuringiensis sub spp israelensis) were analyzed and compared with the...
Ross Overbeek, Tadhg Begley, Ralph M. Butler, Jomuna V. Choudhuri, Terry Disz, Elizabeth M. Glass, ...
Overbeek, Ross, Begley, Tadhg, Butler, Ralph M., Choudhuri, Jomuna V., Chuang, Han-Yu, Cohoon, Matthew, ...
The release of the 1000th complete microbial genome will occur in the next two to three years. In anticipation of this milestone, the Fellowship for Interpretation of Genomes (FIG) launched the...
Automatic detection of subsystem/pathway variants in genome analysis (2005)
Ye, Yuzhen, Osterman, Andrei, Overbeek, Ross, Godzik, Adam
Motivation: Proteins work together in pathways and networks, collectively comprising the cellular machinery. A subsystem (a generalization of pathway concept) is a group of related functional roles...
Kapatral, Vinayak, Ivanova, Natalia, Anderson, Iain, Reznik, Gary, Bhattacharyya, Anamitra, Gardner, Warren L., ...
We present the draft genome sequence and its analysis for Fusobacterium nucleatum sub spp. vincentii (FNV), and compare that genome with F. nucleatum ATCC 25586 (FN). A total of 441 FNV open reading...
The ERGOTM genome analysis and discovery system (2003)
Overbeek, Ross, Larsen, Niels, Walunas, Theresa, D'Souza, Mark, Pusch, Gordon, Selkov, Eugene, ...
The ERGOTM (http://ergo.integratedgenomics.com/ERGO/) genome analysis and discovery suite is an integration of biological data from genomics, biochemistry, high-throughput expression profiling,...
Discovering lactic acid bacteria by genomics (2002)
Klaenhammer, Todd, Altermann, Eric, Arigoni, Fabrizio, Bolotin, Alexander, Breidt, Fred, Broadbent, Jeffrey, ...
This review summarizes a collection of lactic acid bacteria that are now undergoing genomic sequencing and analysis. Summaries are presented on twenty different species, with each overview discussing...
Discovering lactic acid bacteria by genomics (2002)
Klaenhammer, Todd, Altermann, Eric, Arigoni, Fabrizio, Bolotin, Alexander, Breidt, Fred, Broadbent, Jeffrey, ...
This review summarizes a collection of lactic acid bacteria that are now undergoing genomic sequencing and analysis. Summaries are presented on twenty different species, with each overview discussing...
DOI: 10.1093/nar/gkg148 The ERGO TM genome analysis and discovery system (2002)
Ross Overbeek, Niels Larsen, Theresa Walunas, Gordon Pusch, Eugene Selkov, Konstantinos Liolios, ...
The ERGO TM
Bhattacharyya, Anamitra, Stilwagen, Stephanie, Reznik, Gary, Feil, Helene, Feil, William S., Anderson, Iain, ...
Bhattacharyya, Anamitra, Stilwagen, Stephanie, Reznik, Gary, Feil, Helene, Feil, William S., Anderson, Iain, ...
Deppenmeier, Uwe, Johann, André, Hartsch, Thomas, Merkl, Rainer, Schmitz, Ruth A:, Martinez-Arias, Rosa, ...
The Archaeon Methanosarcina mazei and related species are of great ecological importance as they are the only organisms fermenting acetate, methylamines and methanol to methane, carbon dioxide and...
The RDP-II (Ribosomal Database Project (2001)
Bonnie L. Maidak, Gary J. Olsen, Niels Larsen, Ross Overbeek, Michael J. Mccaughey, Carl R. Woese
The Ribosomal Database Project (RDP) is a curated database that offers ribosome-related data, analysis services and associated computer programs. The offerings include phylogenetically ordered...
Overbeek, Ross, Larsen, Niels, Pusch, Gordon D., DSouza, Mark, Jr, Evgeni Selkov, Kyrpides, Nikos, ...
The WIT (What Is There) (http://wit.mcs.anl.gov/WIT2/ ) system has been designed to support comparative analysis of sequenced genomes and to generate metabolic reconstructions based...
Kyrpides, Nikos C., Ouzounis, Christos A., Iliopoulos, Ioannis, Vonstein, Veronika, Overbeek, Ross
The proliferation of genome sequence data has led to the development of a number of tools and strategies that facilitate computational analysis. These methods include the identification of motif...
The Use of Gene Clusters to Infer Functional Coupling (1998)
Ross Overbeek, Michael Fonstein, Mark D'Souza, Natalia Maltsev, Gordon D. Pusch
Earlier, we presented evidence that it is possible to predict functional coupling between genes based on conservation of gene clusters between genomes. With the rapid increase in availability of...
The metabolic pathway collection: an update (1997)
Miliusha Galimova, Igor Goryanin, Yuri Gretchkin, Natalia Ivanova, Yuri Komarov, Natalia Maltsev, ...
The Metabolic Pathway Collection from EMP is an extraction of data from the larger Enzymes and Metabolic Pathways database (EMP). This extraction has been made publicly available in the hope that...
The metabolic pathway collection from EMP: The enzymes and metabolic pathways database (1996)
Svetlana Basmanova, Terry Gaasterl, Igor Goryanin, Yuri Gretchkin, Natalia Maltsev, Valeri Nenashev, ...
The Enzymes and Metabolic Pathways database (EMP) is an encoding of the contents of over 10 000 original publications on the topics of enzymology and metabolism. This large body of information has...
Genetic Sequence Analysis: The Grand Challenge (1995)
Terry Gaasterland, Ross Overbeek
B B B B B B B B B B B B B P P P P hhhhhh h % % " " ¸ ¸ @ @ @ \Pi \Pi \Pi \Pi \Pi \Pi \Pi \Gamma \Gamma i i i \Gamma \Gamma \Gamma \Gamma Z Z fi fi fi fi fi i i i i \Gamma \Gamma \Gamma...
Automating the Determination of 3D Protein Structure (1994)
Karen Rayl, Terry Gaasterl, Ross Overbeek
. The creation of an automated method for determining 3D protein structure would be invaluable to the field of biology and presents an interesting challenge to computer science. Unfortunately, given...
Olsen, Gary J., Matsuda, Hideo, Hagstrom, Ray, Overbeek, Ross
We have developed a new tool, called fastDNAml, for constructing phylogenetic trees from DNA sequences. The program can be run on a wide variety of computers ranging from Unix workstations to...
The Ribosomal Database project (1994)
Maidak, Bonnie L., Larsen, Niels, McCaughey, Michael J., Overbeek, Ross, Olsen, Gary J., Fogel, Karl, ...
The Ribosomal Database Project (RDP) is a curated database that offers ribosome-related data, analysis services, and associated computer programs. The offerings include phylogenetically ordered...
Applications of the Aurora Parallel Prolog System to Computational Molecular Biology (1993)
Ewing Lusk, Shyam Mudambi, Ecrc Gmbh, Ross Overbeek
We describe an investigation into the use of the Aurora parallel Prolog system in two applications within the area of computational molecular biology. The computational requirements were large, due...
The ribosomal database project (1993)
Larsen, Niels, Olsen, Gary J., Maidak, Bonnie L., McCaughey, Michael J., Overbeek, Ross, Macke, Thomas J., ...
The Ribosomal Database Project (RDP) is a curated database that offers ribosome data along with related programs and services. The offerings include phylogenetically ordered alignments of ribosomal...
An integrated database to support research on escherichia coli (1992)
Ra Baehr, George Dunham, Adam Ginsburg, Ray Hagstrom, David Joerg, Toni Kazic, ...
by the Office of Energy Research, U.S. Department of Energy, under Contract W-31-109-Eng-38. 1
The Ribosomal Database Project (1992)
Olsen, Gary J., Overbeek, Ross, Larsen, Niels, Marsh, Terry L., McCaughey, Michael J., Maciukenas, Michael A., ...
The Ribosomal Database Project (RDP) compiles ribosomal sequences and related data, and redistributes them in aligned and phylogenetically ordered form to its user community. It also offers various...
Parallel Adaptive Numerical Schemes For (1987)
Hyperbolic Systems Of, Bradley J. Lucier, Ross Overbeek
We generalize the first author's adaptive numerical scheme for scalar first order conservation laws to systems of equations. The resulting numerical methods generate highly non-uniform,...
THE REPRESENTATION OF MANY-ONE DEGREES BY THE WORD PROBLEM FOR THUE SYSTEMS! (1971)
The object of this paper is to show that, given any total recursive function g, one can effectively construct a Thue system T such that the decision problem for the range of g and the word problem...
The SEED: A Peer-to-Peer Environment for Genome Annotation (0000)
The article discusses the use of SEED, a tool kit created for studying genomics. Genome annotation is the most important areas in genomics today. It is the process of identifying the functions of...
The use of gene clusters to infer functional coupling
Overbeek, Ross, Fonstein, Michael, D’Souza, Mark, Pusch, Gordon D., Maltsev, Natalia
Previously, we presented evidence that it is possible to predict functional coupling between genes based on conservation of gene clusters between genomes. With the rapid increase in the availability...
Graham, David E., Overbeek, Ross, Olsen, Gary J., Woese, Carl R.
Comparisons of complete genome sequences allow the most objective and comprehensive descriptions possible of a lineage's evolution. This communication uses the completed genomes from four major...
Functional analysis of gapped microbial genomes: Amino acid metabolism of Thiobacillus ferrooxidans
Selkov, Evgeni, Overbeek, Ross, Kogan, Yakov, Chu, Lien, Vonstein, Veronika, Holmes, David, ...
A gapped genome sequence of the biomining bacterium Thiobacillus ferrooxidans strain ATCC23270 was assembled from sheared DNA fragments (3.2-times coverage) into 1,912 contigs. A total of 2,712...
Archaeal Shikimate Kinase, a New Member of the GHMP-Kinase Family
Daugherty, Matthew, Vonstein, Veronika, Overbeek, Ross, Osterman, Andrei
Shikimate kinase (EC 2.7.1.71) is a committed enzyme in the seven-step biosynthesis of chorismate, a major precursor of aromatic amino acids and many other aromatic compounds. Genes for all enzymes...
WIT: integrated system for high-throughput genome sequence analysis and metabolic reconstruction
Overbeek, Ross, Larsen, Niels, Pusch, Gordon D., D’Souza, Mark, Jr, Evgeni Selkov, Kyrpides, Nikos, ...
The WIT (What Is There) (http://wit.mcs.anl.gov/WIT2/ ) system has been designed to support comparative analysis of sequenced genomes and to generate metabolic reconstructions based on chromosomal...
Kyrpides, Nikos C., Ouzounis, Christos A., Iliopoulos, Ioannis, Vonstein, Veronika, Overbeek, Ross
The proliferation of genome sequence data has led to the development of a number of tools and strategies that facilitate computational analysis. These methods include the identification of motif...
The genome sequence of the facultative intracellular pathogen Brucella melitensis
DelVecchio, Vito G., Kapatral, Vinayak, Redkar, Rajendra J., Patra, Guy, Mujer, Cesar, Los, Tamara, ...
Brucella melitensis is a facultative intracellular bacterial pathogen that causes abortion in goats and sheep and Malta fever in humans. The genome of B. melitensis strain 16M was sequenced and found...
Whole-genome comparative analysis of three phytopathogenic Xylella fastidiosa strains
Bhattacharyya, Anamitra, Stilwagen, Stephanie, Ivanova, Natalia, D'Souza, Mark, Bernal, Axel, Lykidis, Athanasios, ...
Xylella fastidiosa (Xf) causes wilt disease in plants and is responsible for major economic and crop losses globally. Owing to the public importance of this phytopathogen we embarked on a comparative...
Genome Sequence and Analysis of the Oral Bacterium Fusobacterium nucleatum Strain ATCC 25586
Kapatral, Vinayak, Anderson, Iain, Ivanova, Natalia, Reznik, Gary, Los, Tamara, Lykidis, Athanasios, ...
We present a complete DNA sequence and metabolic analysis of the dominant oral bacterium Fusobacterium nucleatum. Although not considered a major dental pathogen on its own, this anaerobe facilitates...
Genes for the cytoskeletal protein tubulin in the bacterial genus Prosthecobacter
Jenkins, Cheryl, Samudrala, Ram, Anderson, Iain, Hedlund, Brian P., Petroni, Giulio, Michailova, Natasha, ...
Tubulins, the protein constituents of the microtubule cytoskeleton, are present in all known eukaryotes but have never been found in the Bacteria or Archaea. Here we report the presence of two...
The ERGOTM genome analysis and discovery system
Overbeek, Ross, Larsen, Niels, Walunas, Theresa, D'Souza, Mark, Pusch, Gordon, Selkov, Eugene, ...
The ERGOTM (http://ergo.integratedgenomics.com/ERGO/) genome analysis and discovery suite is an integration of biological data from genomics, biochemistry, high-throughput expression profiling,...
Bhattacharyya, Anamitra, Stilwagen, Stephanie, Reznik, Gary, Feil, Helene, Feil, William S., Anderson, Iain, ...
Draft sequencing is a rapid and efficient method for determining the near-complete sequence of microbial genomes. Here we report a comparative analysis of one complete and two draft genome sequences...
The Ribosomal Database Project
Olsen, Gary J., Overbeek, Ross, Larsen, Niels, Marsh, Terry L., McCaughey, Michael J., Maciukenas, Michael A., ...
The Ribosomal Database Project (RDP) compiles ribosomal sequences and related data, and redistributes them in aligned and phylogenetically ordered form to its user community. It also offers various...
Kapatral, Vinayak, Ivanova, Natalia, Anderson, Iain, Reznik, Gary, Bhattacharyya, Anamitra, Gardner, Warren L., ...
We present the draft genome sequence and its analysis for Fusobacterium nucleatum sub spp. vincentii (FNV), and compare that genome with F. nucleatum ATCC 25586 (FN). A total of 441 FNV open reading...
The Subsystems Approach to Genome Annotation and its Use in the Project to Annotate 1000 Genomes
Overbeek, Ross, Begley, Tadhg, Butler, Ralph M., Choudhuri, Jomuna V., Chuang, Han-Yu, Cohoon, Matthew, ...
The release of the 1000th complete microbial genome will occur in the next two to three years. In anticipation of this milestone, the Fellowship for Interpretation of Genomes (FIG) launched the...
Roberts, Corbette, Anderson, Kelsi L., Murphy, Ellen, Projan, Steven J., Mounts, William, Hurlburt, Barry, ...
Bacterial pathogens regulate virulence factor expression at both the level of transcription initiation and mRNA processing/turnover. Within Staphylococcus aureus, virulence factor transcript...
Comparative Genomics of NAD Biosynthesis in Cyanobacteria
Gerdes, Svetlana Y., Kurnasov, Oleg V., Shatalin, Konstantin, Polanuyer, Boris, Sloutsky, Roman, Vonstein, Veronika, ...
Biosynthesis of NAD(P) cofactors is of special importance for cyanobacteria due to their role in photosynthesis and respiration. Despite significant progress in understanding NAD(P) biosynthetic...
The use of gene clusters to infer functional coupling
Overbeek, Ross, Fonstein, Michael, D’Souza, Mark, Pusch, Gordon D., Maltsev, Natalia
Previously, we presented evidence that it is possible to predict functional coupling between genes based on conservation of gene clusters between genomes. With the rapid increase in the availability...
Graham, David E., Overbeek, Ross, Olsen, Gary J., Woese, Carl R.
Comparisons of complete genome sequences allow the most objective and comprehensive descriptions possible of a lineage's evolution. This communication uses the completed genomes from four major...
Functional analysis of gapped microbial genomes: Amino acid metabolism of Thiobacillus ferrooxidans
Selkov, Evgeni, Overbeek, Ross, Kogan, Yakov, Chu, Lien, Vonstein, Veronika, Holmes, David, ...
A gapped genome sequence of the biomining bacterium Thiobacillus ferrooxidans strain ATCC23270 was assembled from sheared DNA fragments (3.2-times coverage) into 1,912 contigs. A total of 2,712...
Archaeal Shikimate Kinase, a New Member of the GHMP-Kinase Family
Daugherty, Matthew, Vonstein, Veronika, Overbeek, Ross, Osterman, Andrei
Shikimate kinase (EC 2.7.1.71) is a committed enzyme in the seven-step biosynthesis of chorismate, a major precursor of aromatic amino acids and many other aromatic compounds. Genes for all enzymes...
WIT: integrated system for high-throughput genome sequence analysis and metabolic reconstruction
Overbeek, Ross, Larsen, Niels, Pusch, Gordon D., D’Souza, Mark, Jr, Evgeni Selkov, Kyrpides, Nikos, ...
The WIT (What Is There) (http://wit.mcs.anl.gov/WIT2/ ) system has been designed to support comparative analysis of sequenced genomes and to generate metabolic reconstructions based on chromosomal...
Kyrpides, Nikos C., Ouzounis, Christos A., Iliopoulos, Ioannis, Vonstein, Veronika, Overbeek, Ross
The proliferation of genome sequence data has led to the development of a number of tools and strategies that facilitate computational analysis. These methods include the identification of motif...
The genome sequence of the facultative intracellular pathogen Brucella melitensis
DelVecchio, Vito G., Kapatral, Vinayak, Redkar, Rajendra J., Patra, Guy, Mujer, Cesar, Los, Tamara, ...
Brucella melitensis is a facultative intracellular bacterial pathogen that causes abortion in goats and sheep and Malta fever in humans. The genome of B. melitensis strain 16M was sequenced and found...
Whole-genome comparative analysis of three phytopathogenic Xylella fastidiosa strains
Bhattacharyya, Anamitra, Stilwagen, Stephanie, Ivanova, Natalia, D'Souza, Mark, Bernal, Axel, Lykidis, Athanasios, ...
Xylella fastidiosa (Xf) causes wilt disease in plants and is responsible for major economic and crop losses globally. Owing to the public importance of this phytopathogen we embarked on a comparative...
Genome Sequence and Analysis of the Oral Bacterium Fusobacterium nucleatum Strain ATCC 25586
Kapatral, Vinayak, Anderson, Iain, Ivanova, Natalia, Reznik, Gary, Los, Tamara, Lykidis, Athanasios, ...
We present a complete DNA sequence and metabolic analysis of the dominant oral bacterium Fusobacterium nucleatum. Although not considered a major dental pathogen on its own, this anaerobe facilitates...
Genes for the cytoskeletal protein tubulin in the bacterial genus Prosthecobacter
Jenkins, Cheryl, Samudrala, Ram, Anderson, Iain, Hedlund, Brian P., Petroni, Giulio, Michailova, Natasha, ...
Tubulins, the protein constituents of the microtubule cytoskeleton, are present in all known eukaryotes but have never been found in the Bacteria or Archaea. Here we report the presence of two...
The ERGOTM genome analysis and discovery system
Overbeek, Ross, Larsen, Niels, Walunas, Theresa, D'Souza, Mark, Pusch, Gordon, Selkov, Eugene, ...
The ERGOTM (http://ergo.integratedgenomics.com/ERGO/) genome analysis and discovery suite is an integration of biological data from genomics, biochemistry, high-throughput expression profiling,...
Bhattacharyya, Anamitra, Stilwagen, Stephanie, Reznik, Gary, Feil, Helene, Feil, William S., Anderson, Iain, ...
Draft sequencing is a rapid and efficient method for determining the near-complete sequence of microbial genomes. Here we report a comparative analysis of one complete and two draft genome sequences...
The Ribosomal Database Project
Olsen, Gary J., Overbeek, Ross, Larsen, Niels, Marsh, Terry L., McCaughey, Michael J., Maciukenas, Michael A., ...
The Ribosomal Database Project (RDP) compiles ribosomal sequences and related data, and redistributes them in aligned and phylogenetically ordered form to its user community. It also offers various...
Kapatral, Vinayak, Ivanova, Natalia, Anderson, Iain, Reznik, Gary, Bhattacharyya, Anamitra, Gardner, Warren L., ...
We present the draft genome sequence and its analysis for Fusobacterium nucleatum sub spp. vincentii (FNV), and compare that genome with F. nucleatum ATCC 25586 (FN). A total of 441 FNV open reading...
The Subsystems Approach to Genome Annotation and its Use in the Project to Annotate 1000 Genomes
Overbeek, Ross, Begley, Tadhg, Butler, Ralph M., Choudhuri, Jomuna V., Chuang, Han-Yu, Cohoon, Matthew, ...
The release of the 1000th complete microbial genome will occur in the next two to three years. In anticipation of this milestone, the Fellowship for Interpretation of Genomes (FIG) launched the...
Roberts, Corbette, Anderson, Kelsi L., Murphy, Ellen, Projan, Steven J., Mounts, William, Hurlburt, Barry, ...
Bacterial pathogens regulate virulence factor expression at both the level of transcription initiation and mRNA processing/turnover. Within Staphylococcus aureus, virulence factor transcript...
Comparative Genomics of NAD Biosynthesis in Cyanobacteria
Gerdes, Svetlana Y., Kurnasov, Oleg V., Shatalin, Konstantin, Polanuyer, Boris, Sloutsky, Roman, Vonstein, Veronika, ...
Biosynthesis of NAD(P) cofactors is of special importance for cyanobacteria due to their role in photosynthesis and respiration. Despite significant progress in understanding NAD(P) biosynthetic...
Anderson, Kelsi L., Roberts, Corbette, Disz, Terrence, Vonstein, Veronika, Hwang, Kaitlyn, Overbeek, Ross, ...
Despite its being a leading cause of nosocomal and community-acquired infections, surprisingly little is known about Staphylococcus aureus stress responses. In the current study, Affymetrix S. aureus...
McNeil, Leslie Klis, Reich, Claudia, Aziz, Ramy K., Bartels, Daniela, Cohoon, Matthew, Disz, Terry, ...
The National Microbial Pathogen Data Resource (NMPDR) () is a National Institute of Allergy and Infections Disease (NIAID)-funded Bioinformatics Resource Center that supports research in selected...
The SEED: A Peer-to-Peer Environment for Genome Annotation
The article discusses the use of SEED, a tool kit created for studying genomics. Genome annotation is the most important areas in genomics today. It is the process of identifying the functions of...
Bonner, Carol A., Disz, Terrence, Hwang, Kaitlyn, Song, Jian, Vonstein, Veronika, Overbeek, Ross, ...
Summary: Many enzymes and other proteins are difficult subjects for bioinformatic analysis because they exhibit variant catalytic, structural, regulatory, and fusion mode features within a protein...
FIGfams: yet another set of protein families
Meyer, Folker, Overbeek, Ross, Rodriguez, Alex
We present FIGfams, a new collection of over 100 000 protein families that are the product of manual curation and close strain comparison. Using the Subsystem approach the manual curation is carried...