AMPK and TNF-{alpha} at the crossroad of cell survival and death in ischaemic heart (2009)
Peng, Wei, Zhang, Yan, Zhu, Weizhong, Cao, Chun-Mei, Xiao, Rui-Ping
Cross-talk of opioid peptide receptor and {beta}-adrenergic receptor signalling in the heart (2004)
Pepe, Salvatore, Lakatta, Edward G, Xiao, Rui-Ping
Opioid peptide receptor (OPR) and β-adrenergic receptor (β-AR) are well-established members of G-protein-coupled receptor (GPCR) superfamily and are involved in regulating cardiac contractility,...
Zhu, Wei-Zhong, Zheng, Ming, Koch, Walter J., Lefkowitz, Robert J., Kobilka, Brian K., Xiao, Rui-Ping
The goal of this study was to determine whether β1-adrenergic receptor (AR) and β2-AR differ in regulating cardiomyocyte survival and apoptosis and, if so, to explore underlying mechanisms. One...
The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy
Liao, Pu, Georgakopoulos, Dimitrios, Kovacs, Attila, Zheng, Meizi, Lerner, Deborah, Pu, Haiying, ...
Stress-induced mitogen-activated protein kinase (MAP) p38 is activated in various forms of heart failure, yet its effects on the intact heart remain to be established. Targeted activation of p38 MAP...
Zhu, Wei-Zhong, Wang, Shi-Qiang, Chakir, Khalid, Yang, Dongmei, Zhang, Tong, Brown, Joan Heller, ...
β1-adrenergic receptor (β1AR) stimulation activates the classic cAMP/protein kinase A (PKA) pathway to regulate vital cellular processes from the change of gene expression to the control of...
Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart
Ding, Jian-Hua, Xu, Xiangdong, Yang, Dongmei, Chu, Pao-Hsien, Dalton, Nancy D, Ye, Zhen, ...
Many genetic diseases are caused by mutations in cis-acting splicing signals, but few are triggered by defective trans-acting splicing factors. Here we report that tissue-specific ablation of the...
Zhu, Wei-Zhong, Zheng, Ming, Koch, Walter J., Lefkowitz, Robert J., Kobilka, Brian K., Xiao, Rui-Ping
The goal of this study was to determine whether β1-adrenergic receptor (AR) and β2-AR differ in regulating cardiomyocyte survival and apoptosis and, if so, to explore underlying mechanisms. One...
The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy
Liao, Pu, Georgakopoulos, Dimitrios, Kovacs, Attila, Zheng, Meizi, Lerner, Deborah, Pu, Haiying, ...
Stress-induced mitogen-activated protein kinase (MAP) p38 is activated in various forms of heart failure, yet its effects on the intact heart remain to be established. Targeted activation of p38 MAP...
Zhu, Wei-Zhong, Wang, Shi-Qiang, Chakir, Khalid, Yang, Dongmei, Zhang, Tong, Brown, Joan Heller, ...
β1-adrenergic receptor (β1AR) stimulation activates the classic cAMP/protein kinase A (PKA) pathway to regulate vital cellular processes from the change of gene expression to the control of...
Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart
Ding, Jian-Hua, Xu, Xiangdong, Yang, Dongmei, Chu, Pao-Hsien, Dalton, Nancy D, Ye, Zhen, ...
Many genetic diseases are caused by mutations in cis-acting splicing signals, but few are triggered by defective trans-acting splicing factors. Here we report that tissue-specific ablation of the...
Zhou, Ying-Ying, Song, Long-Sheng, Lakatta, Edward G, Xiao, Rui-Ping, Cheng, Heping
Transgenic overexpression of the β2-adrenergic receptor (β2AR) in mouse heart augments baseline cardiac function in a ligand-independent manner, due to the presence of spontaneously active β2AR...