Molecular characterization of EGFR, PDGFRA and VEGFR2 in cervical adenosquamous carcinoma (2009)
Longatto-Filho, Adhemar, Pinheiro, Céline, Martinho, Olga, Moreira, Marise AR, Ribeiro, Luiz FJ, Queiroz, Geraldo S, ...
Abstract Background Adenosquamous carcinoma of the uterine cervix is an infrequent but aggressive subtype of cervical cancer. A better understanding of its biological behaviour is warranted to define...
Tineke E Buffart, Beatriz Carvalho, Thomas Mons, Rui M Reis, Cátia Moutinho, Paula Silva, ...
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DNA copy number profiles of gastric cancer precursor lesions (2007)
Buffart, Tineke E, Carvalho, Beatriz, Mons, Thomas, Reis, Rui M, Moutinho, Cátia, Silva, Paula, ...
Abstract Background Chromosomal instability (CIN) is the most prevalent type of genomic instability in gastric tumours, but its role in malignant transformation of the gastric mucosa is still...
Carvalho, Inês, Milanezi, Fernanda, Martins, Albino, Reis, Rui M, Schmitt, Fernando
Abstract Introduction Receptor tyrosine kinases have been extensively studied owing to their frequently abnormal activation in the development and progression of human cancers. Platelet-derived...
Genetic Profile of Gliosarcomas
Reis, Rui M., Könü-Lebleblicioglu, Dilek, Lopes, Jose Manuel, Kleihues, Paul, Ohgaki, Hiroko
There are distinct genetic pathways leading to the glioblastoma, the most malignant astrocytic brain tumor. Primary (de novo) glioblastomas develop in older patients and are characterized by...
Fujisawa, Hironori, Kurrer, Michael, Reis, Rui M., Yonekawa, Yasuhiro, Kleihues, Paul, Ohgaki, Hiroko
Loss of heterozygosity on chromosome 10 (LOH#10) is the most frequent genetic alteration in glioblastomas and occurs in more than 80% of cases. We recently reported that PTEN (MMAC1) on 10q23.3 is...
DNA copy number profiles of gastric cancer precursor lesions
Buffart, Tineke E, Carvalho, Beatriz, Mons, Thomas, Reis, Rui M, Moutinho, Cátia, Silva, Paula, ...