Rune Linding

Directional and quantitative phosphorylation networks (2008)

Jørgensen, Claus, Linding, Rune

Directionality in protein signalling networks is due to modulated protein–protein interactions and is fundamental for proper signal progression and response to external and internal cues. This...

NetworKIN: a resource for exploring cellular phosphorylation networks (2008)

Linding, Rune, Jensen, Lars Juhl, Pasculescu, Adrian, Olhovsky, Marina, Colwill, Karen, Bork, Peer, ...

Protein kinases control cellular responses by phosphorylating specific substrates. Recent proteome-wide mapping of protein phosphorylation sites by mass spectrometry has discovered thousands of in...

Systematic Discovery of New Recognition Peptides Mediating Protein Interaction Networks (2005)

Victor Neduva, Rune Linding, Isabelle Su-Angrand, Alexander Stark, Federico De Masi, Toby J. Gibson, ...

Many protein interactions are mediated by short amino acid motifs. The authors describe a new approach to identify these interaction motifs and experimentally validate some of their binding...

Systematic Discovery of New Recognition Peptides Mediating Protein Interaction Networks (2005)

Victor Neduva, Rune Linding, Isabelle Su-Angrand, Alexander Stark, Federico De Masi, Toby J. Gibson, ...

Many aspects of cell signalling, trafficking, and targeting are governed by interactions between globular protein domains and short peptide segments. These domains often bind multiple peptides that...

Phospho.ELM: A database of experimentally verified phosphorylation sites in eukaryotic proteins (2004)

Diella, Francesca, Cameron, Scott, Gemünd, Christine, Linding, Rune, Via, Allegra, Kuster, Bernhard, ...

Abstract Background Post-translational phosphorylation is one of the most common protein modifications. Phosphoserine, threonine and tyrosine residues play critical roles in the regulation of many...

ELM server: a new resource for investigating short functional sites in modular eukaryotic proteins (2003)

Rune Linding, Christine Gemünd, Sophie Chabanis-davidson, Morten Mattingsdal, Scott Cameron, ...

Multidomain proteins predominate in eukaryotic proteomes. Individual functions assigned to different sequence segments combine to create a complex function for the whole protein. While on-line...

ELM server: a new resource for investigating short functional sites in modular eukaryotic proteins (2003)

Puntervoll, Pål, Linding, Rune, Gemünd, Christine, Chabanis-Davidson, Sophie, Mattingsdal, Morten, Cameron, Scott, ...

Multidomain proteins predominate in eukaryotic proteomes. Individual functions assigned to different sequence segments combine to create a complex function for the whole protein. While on-line...

GlobPlot: exploring protein sequences for globularity and disorder (2003)

Linding, Rune, Russell, Robert B., Neduva, Victor, Gibson, Toby J.

A major challenge in the proteomics and structural genomics era is to predict protein structure and function, including identification of those proteins that are partially or wholly unstructured....

BLAST2SRS, a web server for flexible retrieval of related protein sequences in the SWISS-PROT and SPTrEMBL databases (2003)

Bimpikis, Konstantinos, Budd, Aidan, Linding, Rune, Gibson, Toby J.

SRS (Sequence Retrieval System) is a widely used keyword search engine for querying biological databases. BLAST2 is the most widely used tool to query databases by sequence similarity search. These...

BLAST2SRS, a web server for flexible retrieval of related protein sequences in the SWISS-PROT and SPTrEMBL databases

Bimpikis, Konstantinos, Budd, Aidan, Linding, Rune, Gibson, Toby J.

SRS (Sequence Retrieval System) is a widely used keyword search engine for querying biological databases. BLAST2 is the most widely used tool to query databases by sequence similarity search. These...

ELM server: a new resource for investigating short functional sites in modular eukaryotic proteins

Puntervoll, Pål, Linding, Rune, Gemünd, Christine, Chabanis-Davidson, Sophie, Mattingsdal, Morten, Cameron, Scott, ...

Multidomain proteins predominate in eukaryotic proteomes. Individual functions assigned to different sequence segments combine to create a complex function for the whole protein. While on-line...

GlobPlot: exploring protein sequences for globularity and disorder

Linding, Rune, Russell, Robert B., Neduva, Victor, Gibson, Toby J.

A major challenge in the proteomics and structural genomics era is to predict protein structure and function, including identification of those proteins that are partially or wholly unstructured....

WW Domains Provide a Platform for the Assembly of Multiprotein Networks†

Ingham, Robert J., Colwill, Karen, Howard, Caley, Dettwiler, Sabine, Lim, Caesar S. H., Yu, Joanna, ...

WW domains are protein modules that mediate protein-protein interactions through recognition of proline-rich peptide motifs and phosphorylated serine/threonine-proline sites. To pursue the functional...

Systematic Discovery of New Recognition Peptides Mediating Protein Interaction Networks

Neduva, Victor, Linding, Rune, Su-Angrand, Isabelle, Stark, Alexander, De Masi, Federico, Gibson, Toby J, ...

Many aspects of cell signalling, trafficking, and targeting are governed by interactions between globular protein domains and short peptide segments. These domains often bind multiple peptides that...

BLAST2SRS, a web server for flexible retrieval of related protein sequences in the SWISS-PROT and SPTrEMBL databases

Bimpikis, Konstantinos, Budd, Aidan, Linding, Rune, Gibson, Toby J.

SRS (Sequence Retrieval System) is a widely used keyword search engine for querying biological databases. BLAST2 is the most widely used tool to query databases by sequence similarity search. These...

ELM server: a new resource for investigating short functional sites in modular eukaryotic proteins

Puntervoll, Pål, Linding, Rune, Gemünd, Christine, Chabanis-Davidson, Sophie, Mattingsdal, Morten, Cameron, Scott, ...

Multidomain proteins predominate in eukaryotic proteomes. Individual functions assigned to different sequence segments combine to create a complex function for the whole protein. While on-line...

GlobPlot: exploring protein sequences for globularity and disorder

Linding, Rune, Russell, Robert B., Neduva, Victor, Gibson, Toby J.

A major challenge in the proteomics and structural genomics era is to predict protein structure and function, including identification of those proteins that are partially or wholly unstructured....

WW Domains Provide a Platform for the Assembly of Multiprotein Networks†

Ingham, Robert J., Colwill, Karen, Howard, Caley, Dettwiler, Sabine, Lim, Caesar S. H., Yu, Joanna, ...

WW domains are protein modules that mediate protein-protein interactions through recognition of proline-rich peptide motifs and phosphorylated serine/threonine-proline sites. To pursue the functional...

Systematic Discovery of New Recognition Peptides Mediating Protein Interaction Networks

Neduva, Victor, Linding, Rune, Su-Angrand, Isabelle, Stark, Alexander, De Masi, Federico, Gibson, Toby J, ...

Many aspects of cell signalling, trafficking, and targeting are governed by interactions between globular protein domains and short peptide segments. These domains often bind multiple peptides that...

NetworKIN: a resource for exploring cellular phosphorylation networks

Linding, Rune, Jensen, Lars Juhl, Pasculescu, Adrian, Olhovsky, Marina, Colwill, Karen, Bork, Peer, ...

Protein kinases control cellular responses by phosphorylating specific substrates. Recent proteome-wide mapping of protein phosphorylation sites by mass spectrometry has discovered thousands of in...