Russell E. Bishop

Solution structure and dynamics of the outer membrane enzyme PagP by NMR

Hwang, Peter M., Choy, Wing-Yiu, Lo, Eileen I., Chen, Lu, Forman-Kay, Julie D., Raetz, Christian R. H., ...

The bacterial outer membrane enzyme PagP transfers a palmitate chain from a phospholipid to lipid A. In a number of pathogenic Gram-negative bacteria, PagP confers resistance to certain cationic...

Transfer of palmitate from phospholipids to lipid A in outer membranes of Gram-negative bacteria

Bishop, Russell E., Gibbons, Henry S., Guina, Tina, Trent, M.Stephen, Miller, Samuel I., Raetz, Christian R.H.

Regulated covalent modifications of lipid A are implicated in virulence of pathogenic Gram-negative bacteria. The Salmonella typhimurium PhoP/PhoQ-activated gene pagP is required both for...

An msbB Homologue Carried in Plasmid pO157 Encodes an Acyltransferase Involved in Lipid A Biosynthesis in Escherichia coli O157:H7

Kim, Sang-Hyun, Jia, Wenyi, Bishop, Russell E., Gyles, Carlton

Escherichia coli O157:H7 carries a chromosomal msbB1 and a plasmid-encoded msbB2 gene. We characterized msbB2 function as a homologue of msbB1 by examination of wild-type organisms and mutant strains...

The integral membrane enzyme PagP alternates between two dynamically distinct states

Hwang, Peter M., Bishop, Russell E., Kay, Lewis E.

PhoPQ-activated gene P (PagP) is an integral membrane enzyme that transfers the sn-1 palmitate chain from phospholipid to lipopolysaccharide in Gram-negative bacteria. A recent x-ray crystallographic...

A hydrocarbon ruler measures palmitate in the enzymatic acylation of endotoxin

Ahn, Victoria E, Lo, Eileen I, Engel, Christian K, Chen, Lu, Hwang, Peter M, Kay, Lewis E, ...

The ability of enzymes to distinguish between fatty acyl groups can involve molecular measuring devices termed hydrocarbon rulers, but the molecular basis for acyl-chain recognition in any...

Solution structure and dynamics of the outer membrane enzyme PagP by NMR

Hwang, Peter M., Choy, Wing-Yiu, Lo, Eileen I., Chen, Lu, Forman-Kay, Julie D., Raetz, Christian R. H., ...

The bacterial outer membrane enzyme PagP transfers a palmitate chain from a phospholipid to lipid A. In a number of pathogenic Gram-negative bacteria, PagP confers resistance to certain cationic...

Transfer of palmitate from phospholipids to lipid A in outer membranes of Gram-negative bacteria

Bishop, Russell E., Gibbons, Henry S., Guina, Tina, Trent, M.Stephen, Miller, Samuel I., Raetz, Christian R.H.

Regulated covalent modifications of lipid A are implicated in virulence of pathogenic Gram-negative bacteria. The Salmonella typhimurium PhoP/PhoQ-activated gene pagP is required both for...

An msbB Homologue Carried in Plasmid pO157 Encodes an Acyltransferase Involved in Lipid A Biosynthesis in Escherichia coli O157:H7

Kim, Sang-Hyun, Jia, Wenyi, Bishop, Russell E., Gyles, Carlton

Escherichia coli O157:H7 carries a chromosomal msbB1 and a plasmid-encoded msbB2 gene. We characterized msbB2 function as a homologue of msbB1 by examination of wild-type organisms and mutant strains...

The integral membrane enzyme PagP alternates between two dynamically distinct states

Hwang, Peter M., Bishop, Russell E., Kay, Lewis E.

PhoPQ-activated gene P (PagP) is an integral membrane enzyme that transfers the sn-1 palmitate chain from phospholipid to lipopolysaccharide in Gram-negative bacteria. A recent x-ray crystallographic...

A hydrocarbon ruler measures palmitate in the enzymatic acylation of endotoxin

Ahn, Victoria E, Lo, Eileen I, Engel, Christian K, Chen, Lu, Hwang, Peter M, Kay, Lewis E, ...

The ability of enzymes to distinguish between fatty acyl groups can involve molecular measuring devices termed hydrocarbon rulers, but the molecular basis for acyl-chain recognition in any...

Modulation of Hexa-Acyl Pyrophosphate Lipid A Population under Escherichia coli Phosphate (Pho) Regulon Activation▿

Lamarche, Martin G., Kim, Sang-Hyun, Crépin, Sébastien, Mourez, Michael, Bertrand, Nicolas, Bishop, Russell E., ...

Environmental phosphate is an important signal for microorganism gene regulation, and it has recently been shown to trigger some key bacterial virulence mechanisms. In many bacteria, the Pho regulon...