Ruth Freeman

Health promotion and the randomised controlled trial: a square peg in a round hole? (2009)

Freeman, Ruth

Abstract In their paper published in BMC Oral Health in March, Barker and Horton present qualitative data which explored Latino parents' main concerns regarding accessing dental care for their...

α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II (2008)

Dong, Lan-feng, Low, Pauline, Dyason, Jeffrey Clifford, Wang, Xiufang, Prochazka, L, Witting, PK, ...

α-Tocopheryl succinate (α-TOS) is a selective inducer of apoptosis in cancer cells, which involves the accumulation of reactive oxygen species (ROS). The molecular target of α-TOS has not been...

α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II (2008)

Dong, Lan-feng, Low, Pauline, Dyason, Jeffrey Clifford, Wang, Xiufang, Prochazka, L, Witting, PK, ...

α-Tocopheryl succinate (α-TOS) is a selective inducer of apoptosis in cancer cells, which involves the accumulation of reactive oxygen species (ROS). The molecular target of α-TOS has not been...

α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II (2008)

Dong, Lan-feng, Low, Pauline, Dyason, Jeffrey Clifford, Wang, Xiufang, Prochazka, L, Witting, PK, ...

α-Tocopheryl succinate (α-TOS) is a selective inducer of apoptosis in cancer cells, which involves the accumulation of reactive oxygen species (ROS). The molecular target of α-TOS has not been...

Mitocans as anti-cancer agents targeting mitochondria: lessons from studies with vitamin E analogues, inhibitors of complex II (2007)

Neuzil, Jiri, Dyason, Jeffrey Clifford, Freeman, Ruth, Dong, Lan-feng, Prochazka, Lubomir, Wang, Xiufang, ...

Recently mitochondria in cancer cells have emerged as the Achilles heel for tumour destruction. Anti-cancer agents specifically targeting cancer cell mitochondria are referred to as 'mitocans'. These...

Vitamin E analogues as a novel group of mitocans: anti-cancer agents that act by targeting mitochondria (2007)

Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...

Mitochondria have recently emerged as new and promising targets for cancer prevention and therapy. One of the reasons for this is that mitochondria are instrumental to many types of cell death and...

Mitocans as anti-cancer agents targeting mitochondria: lessons from studies with vitamin E analogues, inhibitors of complex II (2007)

Neuzil, Jiri, Dyason, Jeffrey Clifford, Freeman, Ruth, Dong, Lan-feng, Prochazka, Lubomir, Wang, Xiufang, ...

Recently mitochondria in cancer cells have emerged as the Achilles heel for tumour destruction. Anti-cancer agents specifically targeting cancer cell mitochondria are referred to as 'mitocans'. These...

Vitamin E analogues as a novel group of mitocans: anti-cancer agents that act by targeting mitochondria (2007)

Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...

Mitochondria have recently emerged as new and promising targets for cancer prevention and therapy. One of the reasons for this is that mitochondria are instrumental to many types of cell death and...

Mitocans as anti-cancer agents targeting mitochondria: lessons from studies with vitamin E analogues, inhibitors of complex II (2007)

Neuzil, Jiri, Dyason, Jeffrey Clifford, Freeman, Ruth, Dong, Lan-feng, Prochazka, Lubomir, Wang, Xiufang, ...

Recently mitochondria in cancer cells have emerged as the Achilles heel for tumour destruction. Anti-cancer agents specifically targeting cancer cell mitochondria are referred to as 'mitocans'. These...

Vitamin E analogues as a novel group of mitocans: anti-cancer agents that act by targeting mitochondria (2007)

Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...

Mitochondria have recently emerged as new and promising targets for cancer prevention and therapy. One of the reasons for this is that mitochondria are instrumental to many types of cell death and...

Role of thioredoxin-1 in apoptosis induction by α-tocopheryl succinate and TNF-related apoptosis-inducing ligand in mesothelioma cells (2006)

Freeman, Ruth, Neuzil, Jiri

Malignant mesothelioma (MM) is a fatal type of cancer. We studied the role of the redox-active protein thioredoxin-1 (Trx-1) in apoptosis induced in MM cells and their non-malignant counterparts...

Role of thioredoxin-1 in apoptosis induction by α-tocopheryl succinate and TNF-related apoptosis-inducing ligand in mesothelioma cells (2006)

Freeman, Ruth, Neuzil, Jiri

Malignant mesothelioma (MM) is a fatal type of cancer. We studied the role of the redox-active protein thioredoxin-1 (Trx-1) in apoptosis induced in MM cells and their non-malignant counterparts...

Role of thioredoxin-1 in apoptosis induction by α-tocopheryl succinate and TNF-related apoptosis-inducing ligand in mesothelioma cells (2006)

Freeman, Ruth, Neuzil, Jiri

Malignant mesothelioma (MM) is a fatal type of cancer. We studied the role of the redox-active protein thioredoxin-1 (Trx-1) in apoptosis induced in MM cells and their non-malignant counterparts...

International comparisons of health inequalities in childhood dental caries (2004)

Adair, Pauline M, Nicoll, Alison D, Burnside, Girvan, Petersen, Poul Erik, Beighton, David, ...

OBJECTIVE: To undertake formative studies investigating how the experience of dental caries in young children living in diverse settings relates to familial and cultural perceptions and beliefs, oral...

Familial and cultural perceptions and beliefs of oral hygiene and dietary practices among ethnically and socio-economicall diverse groups (2004)

Pine, Cynthia M, Burnside, Girvan, Nicoll, Alison D, Gillett, Angela, Anwar, Shahid, ...

OBJECTIVE; The aim of this international study was to develop a valid and reliable psychometric measure to examine the extent to which parents' attitudes about engaging in twice-daily tooth brushing...

Developing explanatory models of health inequalities in childhood dental caries (2004)

Adair, Pauline M, Petersen, Poul Erik, Douglass, Chester, Burnside, Girvan, Nicoll, Alison D, ...

OBJECTIVE: Long-term aim is to determine optimum interventions to reduce dental caries in children in disadvantaged communities and minimise the effects of exclusion from health care systems, of...

Critical health promotion and education--a new research challenge (2004)

Simpson, Kirk, Freeman, Ruth

In relation to health promotion and education, the use of post‐positivist and constructivist approaches has been gathering strength in recent years. Despite this emerging tradition, little has...

Reforming NHS dentistry

Freeman, Ruth

Equitable distribution of affordable dental services is still possible

Health promotion and the randomised controlled trial: a square peg in a round hole?

Freeman, Ruth

In their paper published in BMC Oral Health in March, Barker and Horton present qualitative data which explored Latino parents' main concerns regarding accessing dental care for their pre-school...