RhoL controls invasion and Rap1 localization during immune cell transmigration in Drosophila (2010)
Daria Siekhaus, Martin Haesemeyer, Olivia Moffitt, Ruth Lehmann
Kunwar, Prabhat S., Sano, Hiroko, Renault, Andrew D., Barbosa, Vitor, Fuse, Naoyuki, Lehmann, Ruth
Despite significant progress in identifying the guidance pathways that control cell migration, how a cell starts to move within an intact organism, acquires motility, and loses contact with its...
Van Der Knaap, Suzan, Messerli, Ruth, Baronti, Fabio, Lehmann, Ruth, ...
OBJECTIVE: Clinical scales evaluating arm function after stroke are weak at detecting quality of movement. Therefore a new scale, the Motor Evaluation Scale for Upper Extremity in Stroke Patients...
Egalitarian binds dynein light chain to establish oocyte polarity and maintain oocyte fate (2004)
Caryn Navarro, Hamsa Puthalakath, Jerry M. Adams, Andreas Strasser, Ruth Lehmann
Prabhat S. Kunwar, Michelle Starz-Gaiano, Roland J. Bainton, Ulrike Heberlein, Ruth Lehmann
A novel G protein-coupled receptor (GPCR) is shown to be essential for transepithelial migration of Drosophila germ cells. Leukocyte transepithelial migration also requires GPCR signaling, suggesting...
Prabhat S. Kunwar, Michelle Starz-Gaiano, Roland J. Bainton, Ulrike Heberlein, Ruth Lehmann
In most organisms, germ cells are formed distant from the somatic part of the gonad and thus have to migrate along and through a variety of tissues to reach the gonad. Transepithelial migration...
Targeted mRNA degradation by double-stranded RNA in vitro (1999)
Tuschl, Thomas, Zamore, Phillip D., Lehmann, Ruth, Bartel, David P., Sharp, Phillip A.
Schlosser, Manfred, Desponds, Olivier, Lehmann, Ruth, Moret, Etienne, Rauchschwalbe, Guenter
A review with 64 refs., including discussion of the structural flexibility of organometallic species, the stereochem. of 2-alkenylmetal compds., and the origin of the endo effect. [on SciFinder (R)]
The enigmatic 1J(CH) coupling constants of allyl-type organometallic compounds (1990)
Schlosser, Manfred, Lehmann, Ruth, Jenny, Titus
A new attempt has been made to identify the factors responsible for the abnormally small one-bond C, H coupling consts. obsd. for allyl, pentadienyl and heptatrienyl compds. of Li and K. In-plane...
Cross-regulatory interactions among the gap genes of Drosophila (1986)
Herbert Jäckle, Diethard Tautz, Reinhard Schuh, Eveline Seifert, Ruth Lehmann
Staehle, Manfred, Lehmann, Ruth, Kramar, Jaroslav, Schlosser, Manfred
When treated with BuLi and Me3CONa, both norbornadiene and norbornene underwent a H/Na-exchange at the 2-position. The diene, however, reacted approx. 30 times faster with Me3SiCl....
Facile hydrogen/metal exchange between butylpotassium and saturated ethers (1984)
Lehmann, Ruth, Schlosser, Manfred
At temps. between -100 and -40 Deg, lithium salt-free butylpotassium (prepd. from dibutylmercury) readily metalates satd. ethers such as Me2O or THF. [on SciFinder (R)]
Le sémantisme des mots expressifs en Suisse romande. (1949)
Bern, Phil. I Diss. - Auch im Buchh. als : Romanica helvetica. Bd. 34.
Poly(A)-independent regulation of maternal hunchback translation in the Drosophila embryo
Chagnovich, Daniel, Lehmann, Ruth
Development of the Drosophila abdomen requires repression of maternal hunchback (hb) mRNA translation in the posterior of the embryo. This regulation involves at least four components: nanos response...
An essential role of DmRad51/SpnA in DNA repair and meiotic checkpoint control
Staeva-Vieira, Eric, Yoo, Siuk, Lehmann, Ruth
Rad51 is a conserved protein essential for recombinational repair of double-stranded DNA breaks (DSBs) in somatic cells and during meiosis in germ cells. Yeast Rad51 mutants are viable but show...
Tre1, a G Protein-Coupled Receptor, Directs Transepithelial Migration of Drosophila Germ Cells
Kunwar, Prabhat S, Starz-Gaiano, Michelle, Bainton, Roland J, Heberlein, Ulrike, Lehmann, Ruth
In most organisms, germ cells are formed distant from the somatic part of the gonad and thus have to migrate along and through a variety of tissues to reach the gonad. Transepithelial migration...
Targeted mRNA degradation by double-stranded RNA in vitro
Tuschl, Thomas, Zamore, Phillip D., Lehmann, Ruth, Bartel, David P., Sharp, Phillip A.
Double-stranded RNA (dsRNA) directs gene-specific, post-transcriptional silencing in many organisms, including vertebrates, and has provided a new tool for studying gene function. The biochemical...
Morris, Jason Z, Navarro, Caryn, Lehmann, Ruth
The Drosophila oocyte develops from a cluster of 16 interconnected cells that derive from a common progenitor. One of these cells, the oocyte, arrests in meiosis. The other cells endoreplicate their...
l(3)malignant brain tumor and three novel genes are required for Drosophila germ-cell formation.
Yohn, Christopher B, Pusateri, Leslie, Barbosa, Vitor, Lehmann, Ruth
To identify genes involved in the process of germ-cell formation in Drosophila, a maternal-effect screen using the FLP/FRT-ovoD method was performed on chromosome 3R. In addition to expected...
Poly(A)-independent regulation of maternal hunchback translation in the Drosophila embryo
Chagnovich, Daniel, Lehmann, Ruth
Development of the Drosophila abdomen requires repression of maternal hunchback (hb) mRNA translation in the posterior of the embryo. This regulation involves at least four components: nanos response...
An essential role of DmRad51/SpnA in DNA repair and meiotic checkpoint control
Staeva-Vieira, Eric, Yoo, Siuk, Lehmann, Ruth
Rad51 is a conserved protein essential for recombinational repair of double-stranded DNA breaks (DSBs) in somatic cells and during meiosis in germ cells. Yeast Rad51 mutants are viable but show...
Tre1, a G Protein-Coupled Receptor, Directs Transepithelial Migration of Drosophila Germ Cells
Kunwar, Prabhat S, Starz-Gaiano, Michelle, Bainton, Roland J, Heberlein, Ulrike, Lehmann, Ruth
In most organisms, germ cells are formed distant from the somatic part of the gonad and thus have to migrate along and through a variety of tissues to reach the gonad. Transepithelial migration...
Targeted mRNA degradation by double-stranded RNA in vitro
Tuschl, Thomas, Zamore, Phillip D., Lehmann, Ruth, Bartel, David P., Sharp, Phillip A.
Double-stranded RNA (dsRNA) directs gene-specific, post-transcriptional silencing in many organisms, including vertebrates, and has provided a new tool for studying gene function. The biochemical...
Morris, Jason Z, Navarro, Caryn, Lehmann, Ruth
The Drosophila oocyte develops from a cluster of 16 interconnected cells that derive from a common progenitor. One of these cells, the oocyte, arrests in meiosis. The other cells endoreplicate their...
l(3)malignant brain tumor and three novel genes are required for Drosophila germ-cell formation.
Yohn, Christopher B, Pusateri, Leslie, Barbosa, Vitor, Lehmann, Ruth
To identify genes involved in the process of germ-cell formation in Drosophila, a maternal-effect screen using the FLP/FRT-ovoD method was performed on chromosome 3R. In addition to expected...
Barbosa, Vitor, Kimm, Naomi, Lehmann, Ruth
Meiotic checkpoints monitor chromosome status to ensure correct homologous recombination, genomic integrity, and chromosome segregation. In Drosophila, the persistent presence of double-strand DNA...
Sano, Hiroko, Renault, Andrew D., Lehmann, Ruth
In most organisms, primordial germ cells (PGCs) arise far from the region where somatic gonadal precursors (SGPs) are specified. Although PGCs in general originate as a single cluster of cells, the...
Drosophila germ-line modulation of insulin signaling and lifespan
Flatt, Thomas, Min, Kyung-Jin, D'Alterio, Cecilia, Villa-Cuesta, Eugenia, Cumbers, John, Lehmann, Ruth, ...
Ablation of germ-line precursor cells in Caenorhabditis elegans extends lifespan by activating DAF-16, a forkhead transcription factor (FOXO) repressed by insulin/insulin-like growth factor (IGF)...
Kunwar, Prabhat S., Sano, Hiroko, Renault, Andrew D., Barbosa, Vitor, Fuse, Naoyuki, Lehmann, Ruth
Despite significant progress in identifying the guidance pathways that control cell migration, how a cell starts to move within an intact organism, acquires motility, and loses contact with its...
Altered dynein-dependent transport in piRNA pathway mutants
Navarro, Caryn, Bullock, Simon, Lehmann, Ruth
Maintenance of genome integrity in germ cells is crucial for the success of future generations. In Drosophila, and mammals, transposable element activity in the germline can cause DNA breakage and...