Ruud van Winkel

A cross-sectional evaluation of adiponectin plasma levels in patients with schizophrenia and schizoaffective disorder (2008)

Van Winkel, Ruud, Wampers, Martien, Van Eyck, Dominique, Scheen, Andre, Reginster, Jean-Yves, ...

BACKGROUND: In recent years, several studies showed increased rates of hyperglycaemia, diabetes, dyslipidemia, metabolic syndrome as well as cardiovascular disease in schizophrenic patients. The...

Psychiatric diagnosis as an independent risk factor for metabolic disturbances: results from a comprehensive, naturalistic screening program. (2008)

Van Winkel, Ruud, Van Os, Jim, Celic, Ivan, Van Eyck, Dominique, Wampers, Martien, Scheen, André, ...

OBJECTIVE: Unconfounded differences in inherent vulnerability to metabolic disturbance may be hypothesized for different diagnostic groups with severe mental illness. METHOD: A naturalistic cohort of...

Major changes in glucose metabolism, including new-onset diabetes, within 3 months after initiation of or switch to atypical antipsychotic medication in patients with schizophrenia and schizoaffective disorder. (2008)

Van Winkel, Ruud, De Hert, Marc, Wampers, Martien, Van Eyck, Dominique, Hanssens, Linda, Scheen, André, ...

OBJECTIVE: To investigate 3-month changes in glucose metabolism in a naturalistic sample of patients with schizophrenia newly started on or switched to specific atypical antipsychotic medication...

Typical and atypical antipsychotics differentially affect long-term incidence rates of the metabolic syndrome in first-episode patients with schizophrenia: a retrospective chart review. (2008)

De Hert, Marc, Schreurs, Vincent, Sweers, Kim, Van Eyck, Dominique, Hanssens, Linda, Sinko, Sebastjan, ...

The presence of the metabolic syndrome (MetS) is an important risk factor for cardiovascular disease and diabetes. There are limited data on the prevalence of MetS in patients with schizophrenia at...

A cross-sectional evaluation of adiponectin plasma levels in patients with schizophrenia and schizoaffective disorder. (2008)

Hanssens, Linda, Van Winkel, Ruud, Wampers, Martien, Van Eyck, Dominique, Scheen, André, Reginster, Jean-Yves, ...

BACKGROUND: In recent years, several studies showed increased rates of hyperglycaemia, diabetes, dyslipidemia, metabolic syndrome as well as cardiovascular disease in schizophrenic patients. The...

Prevalence of diabetes and the metabolic syndrome in a sample of patients with bipolar disorder. (2008)

Van Winkel, Ruud, De Hert, Marc, Van Eyck, Dominique, Hanssens, Linda, Wampers, Martien, Scheen, André, ...

OBJECTIVES: The presence of metabolic abnormalities is an important risk factor for cardiovascular disease and diabetes. There are limited data on the prevalence of the metabolic abnormalities in...

Psychosocial Stress and Psychosis. A Review of the Neurobiological Mechanisms and the Evidence for Gene-Stress Interaction (2008)

Van Winkel, Ruud, Stefanis, Nicholas C., Myin-Germeys, Inez

This article presents evidence suggesting that psychosocial stress may increase risk for psychosis, especially in the case of cumulative exposure. A heuristically useful framework to study the...

A cross-sectional evaluation of adiponectin plasma levels in patients with schizophrenia and schizoaffective disorder. (2008)

Hanssens, Linda, Van Winkel, Ruud, Wampers, Martien, Van Eyck, Dominique, Scheen, André, Reginster, Jean-Yves, ...

BACKGROUND: In recent years, several studies showed increased rates of hyperglycaemia, diabetes, dyslipidemia, metabolic syndrome as well as cardiovascular disease in schizophrenic patients. The...

Anticholinergic use in hospitalised schizophrenic patients in Belgium (2007)

Wampers, Martien, Van Winkel, Ruud

This naturalistic study aims to evaluate the influence of antipsychotic treatment on the use of anticholinergics. The observed use of anticholinergics will give an indication of the occurrence of...

A Case Series: Evaluation of the Metabolic Safety of Aripiprazole (2007)

De Hert, Marc, Hanssens, Linda, Van Winkel, Ruud, Wampers, Martien, Van Eyck, Dominique, Scheen, Andre, ...

Metabolic abnormalities occur frequently in patients treated with antipsychotics and are of growing concern to clinicians. This study sought to determine whether antipsychotic-associated metabolic...

A Case Series: Evaluation of the Metabolic Safety of Aripiprazole (2007)

Hanssens, Linda, Van Winkel, Ruud, Wampers, Martien, Van Eyck, Dominique, Scheen, Andre, ...

Metabolic abnormalities occur frequently in patients treated with antipsychotics and are of growing concern to clinicians. This study sought to determine whether antipsychotic-associated metabolic...

Pharmacological treatment of severe dyslipidaemia in patients with schizophrenia (2007)

Kalnicka, Dita, Van Winkel, Ruud, Wampers, Martien, Van Eyck, Dominique, ...

Mortality rates in patients with schizophrenia are double compared with the general population, with cardiovascular disease causing 50% of the excess. Lowering low-density lipoprotein cholesterol is...

Treatment with rosuvastatin for severe dyslipidemia in patients with schizophrenia and schizoaffective disorder (2006)

Kalnicka, Dita, Van Winkel, Ruud, Wampers, Martien, Hanssens, Linda, Van Eyck, Dominique, ...

BACKGROUND: Mortality rates in patients with schizophrenia are double compared to those in the general population, with cardiovascular disease causing 50% of the excess. Lowering low-density...

Body weight and self-esteem in patients with schizophrenia evaluated with B-WISE(R) (2006)

Peuskens, Bie, Van Winkel, Ruud, Kalnicka, Dita, Hanssens, Linda, Van Eyck, Dominique, ...

BACKGROUND: Metabolic abnormalities and weight gain are an important problem in patients with schizophrenia. An instrument to evaluate body image and self-esteem related to weight has recently been...

Prevalence of the metabolic syndrome in patients with schizophrenia treated with antipsychotic medication (2006)

De Hert, Marc A., Van Winkel, Ruud, Van Eyck, Dominique, Hanssens, Linda, Wampers, Martien, Scheen, André, ...

The presence of the metabolic syndrome is an important risk factor for cardiovascular disease and diabetes. There are limited data on the prevalence of the metabolic syndrome in European patients...

Prevalence of the metabolic syndrome in patients with schizophrenia treated with antipsychotic medication (2006)

Van Winkel, Ruud, Van Eyck, Dominique, Hanssens, Linda, Wampers, Martien, Scheen, Andre, ...

The presence of the metabolic syndrome is an important risk factor for cardiovascular disease and diabetes. There are limited data on the prevalence of the metabolic syndrome in European patients...

Treatment with rosuvastatin for severe dyslipidemia in patients with schizophrenia and schizoaffective disorder. (2006)

De Hert, Marc, Kalnicka, Dita, Van Winkel, Ruud, Wampers, Martien, Hanssens, Linda, Van Eyck, Dominique, ...

BACKGROUND: Mortality rates in patients with schizophrenia are double compared to those in the general population, with cardiovascular disease causing 50% of the excess. Lowering low-density...

Screening for diabetes and other metabolic abnormalities in patients with schizophrenia and schizoaffective disorder: evaluation of incidence and screening methods. (2006)

Van Winkel, Ruud, De Hert, Marc, Van Eyck, Dominique, Hanssens, Linda, Wampers, Martien, Scheen, André, ...

OBJECTIVE: To assess the diagnostic properties of 2 different screening guidelines for the detection of diabetes in patients diagnosed with schizophrenia. METHOD: Over a 2-year period (November...

A Case Series: Evaluation of the Metabolic Safety of Aripiprazole (2006)

De Hert, Marc, Hanssens, Linda, Van Winkel, Ruud, Wampers, Martien, Van Eyck, Dominique, Scheen, Andre, ...

Metabolic abnormalities occur frequently in patients treated with antipsychotics and are of growing concern to clinicians. This study sought to determine whether antipsychotic-associated metabolic...

A Case Series: Evaluation of the Metabolic Safety of Aripiprazole

De Hert, Marc, Hanssens, Linda, Van Winkel, Ruud, Wampers, Martien, Van Eyck, Dominique, Scheen, Andre, ...

Metabolic abnormalities occur frequently in patients treated with antipsychotics and are of growing concern to clinicians. This study sought to determine whether antipsychotic-associated metabolic...

Metabolic syndrome in people with schizophrenia: a review

DE HERT, MARC, SCHREURS, VINCENT, VANCAMPFORT, DAVY, VAN WINKEL, RUUD

Metabolic syndrome and other cardiovascular risk factors are highly prevalent in people with schizophrenia. Patients are at risk for premature mortality and overall have limited access to physical...

Psychosocial Stress and Psychosis. A Review of the Neurobiological Mechanisms and the Evidence for Gene-Stress Interaction

Van Winkel, Ruud, Stefanis, Nicholas C., Myin-Germeys, Inez

This article presents evidence suggesting that psychosocial stress may increase risk for psychosis, especially in the case of cumulative exposure. A heuristically useful framework to study the...