MIREOT: the Minimum Information to Reference an External Ontology Term (2009)
Melanie Courtot, Frank Gibson, Allyson L. Lister, James Malone, Daniel Schober, Ryan R. Brinkman, ...
While the Web Ontology Language (OWL) provides a mechanism to import ontologies, this mechanism is not always suitable. First, given the current state of editing tools and the issues they have...
MIREOT: the Minimum Information to Reference an External Ontology Term (2009)
Mélanie Courtot, Frank Gibson, Allyson L. Lister, James Malone, Daniel Schober, Ryan R. Brinkman, ...
While the Web Ontology Language (OWL) provides a mechanism to import ontologies, this mechanism is not always suitable. First, given the current state of editing tools and the issues they have...
The OWL of Biomedical Investigations (2009)
Mélanie Courtot, William Bug, Frank Gibson, Allyson L. Lister, Daniel Schober, Ryan R. Brinkman, ...
DL, is being developed by a large consortium seeking to provide a crossdomain, shared framework for representing investigations in the biological and biomedical sciences. In this paper we report our...
Yongqun He, Lindsay Cowell, Alexander D. Diehl, Harry Mobley, Bjoern Peters, Alan Ruttenberg, ...
Vaccine research, as well as the development, testing, clinical trials, and commercial uses of vaccines involve complex processes with various biological data that include gene and protein...
Yongqun He, Lindsay Cowell, Alexander D. Diehl, Harry Mobley, Bjoern Peters, Alan Ruttenberg, ...
The collaborative, community-based Vaccine Ontology (VO) was developed to promote vaccine data standardization, integration, and computer-assisted reasoning. Currently VO covers a variety of aspects...
FuGEFlow: data model and markup language for flow cytometry (2009)
Qian, Yu, Tchuvatkina, Olga, Spidlen, Josef, Wilkinson, Peter, Gasparetto, Maura, Jones, Andrew R, ...
Abstract Background Flow cytometry technology is widely used in both health care and research. The rapid expansion of flow cytometry applications has outpaced the development of data storage and...
flowClust: a Bioconductor package for automated gating of flow cytometry data (2009)
Lo, Kenneth, Hahne, Florian, Brinkman, Ryan R, Gottardo, Raphael
Abstract Background As a high-throughput technology that offers rapid quantification of multidimensional characteristics for millions of cells, flow cytometry (FCM) is widely used in health research,...
flowCore: a Bioconductor package for high throughput flow cytometry (2009)
Hahne, Florian, LeMeur, Nolwenn, Brinkman, Ryan R, Ellis, Byron, Haaland, Perry, Sarkar, Deepayan, ...
Abstract Background Recent advances in automation technologies have enabled the use of flow cytometry for high throughput screening, generating large complex data sets often in clinical trials or...
Analysis of High-Throughput Flow Cytometry Data Using plateCore (2009)
Errol Strain, Florian Hahne, Ryan R. Brinkman, Perry Haaland
Flow cytometry (FCM) software packages from R/Bioconductor, such as flowCore and flowViz, serve as an open platform for development of new analysis tools and methods. We created plateCore, a new...
Analysis of High-Throughput Flow Cytometry Data Using plateCore (2009)
Errol Strain, Florian Hahne, Ryan R. Brinkman, Perry Haaland
Flow cytometry (FCM) software packages from R/Bioconductor, such as flowCore and flowViz, serve as an open platform for development of new analysis tools and methods. We created plateCore, a new...
Data Quality Assessment of Ungated Flow Cytometry Data in High (2007)
Le Meur, Nolwenn, Rossini, Anthony, Gasparetto, Maura, Smith, Clay, Brinkman, Ryan R, Gentleman, Robert
Background: The recent development of semi-automated techniques for staining and analyzing flow cytometry samples has presented new challenges. Quality control and quality assessment are critical...
Data Quality Assessment of Ungated Flow Cytometry Data in High (2007)
Le Meur, Nolwenn, Rossini, Anthony, Gasparetto, Maura, Smith, Clay, Brinkman, Ryan R, Gentleman, Robert
Background: The recent development of semi-automated techniques for staining and analyzing flow cytometry samples has presented new challenges. Quality control and quality assessment are critical...
Data Quality Assessment of Ungated Flow Cytometry Data in High (2007)
Le Meur, Nolwenn, Rossini, Anthony, Gasparetto, Maura, Smith, Clay, Brinkman, Ryan R, Gentleman, Robert
Background: The recent development of semi-automated techniques for staining and analyzing flow cytometry samples has presented new challenges. Quality control and quality assessment are critical...
Data Quality Assessment of Ungated Flow Cytometry Data in High (2007)
Le Meur, Nolwenn, Rossini, Anthony, Gasparetto, Maura, Smith, Clay, Brinkman, Ryan R, Gentleman, Robert
Background: The recent development of semi-automated techniques for staining and analyzing flow cytometry samples has presented new challenges. Quality control and quality assessment are critical...
Langbehn,Douglas R., Brinkman,Ryan R., Falush,Daniel, Paulsen,Jane S., Hayden,M. R.
Huntington's disease (HD) is a neurodegenerative disorder caused by an unstable CAG repeat. For patients at risk, participating in predictive testing and learning of having CAG expansion, a major...
A Genome Scan for Modifiers of Age at Onset in Huntington Disease: The HD MAPS Study
Li, Jian-Liang, Hayden, Michael R., Almqvist, Elisabeth W., Brinkman, Ryan R., Durr, Alexandra, Dodé, Catherine, ...
Huntington disease (HD) is caused by the expansion of a CAG repeat within the coding region of a novel gene on 4p16.3. Although the variation in age at onset is partly explained by the size of the...
Lafrenière, Ronald G., MacDonald, Marcia L. E., Dubé, Marie-Pierre, MacFarlane, Julie, O’Driscoll, Mary, Brais, Bernard, ...
Hereditary sensory and autonomic neuropathy (HSAN) type II is an autosomal recessive disorder characterized by impairment of pain, temperature, and touch sensation owing to reduction or absence of...
flowCore: a Bioconductor package for high throughput flow cytometry
Hahne, Florian, LeMeur, Nolwenn, Brinkman, Ryan R, Ellis, Byron, Haaland, Perry, Sarkar, Deepayan, ...