Søren Kjærulff

Genomewide identification of pheromone-targeted transcription in fission yeast (2006)

Xue-Franzén, Yongtao, Kjærulff, Søren, Holmberg, Christian, Wright, Anthony, Nielsen, Olaf

Abstract Background Fission yeast cells undergo sexual differentiation in response to nitrogen starvation. In this process haploid M and P cells first mate to form diploid zygotes, which then enter...

Constitutive Activation of the Fission Yeast Pheromone-Responsive Pathway Induces Ectopic Meiosis and Reveals Ste11 as a Mitogen-Activated Protein Kinase Target

Kjærulff, Søren, Lautrup-Larsen, Inger, Truelsen, Søren, Pedersen, Morten, Nielsen, Olaf

In the fission yeast Schizosaccharomyces pombe, meiosis normally takes place in diploid zygotes resulting from conjugation of haploid cells. In the present study, we report that the expression of a...

Constitutive Activation of the Fission Yeast Pheromone-Responsive Pathway Induces Ectopic Meiosis and Reveals Ste11 as a Mitogen-Activated Protein Kinase Target

Kjærulff, Søren, Lautrup-Larsen, Inger, Truelsen, Søren, Pedersen, Morten, Nielsen, Olaf

In the fission yeast Schizosaccharomyces pombe, meiosis normally takes place in diploid zygotes resulting from conjugation of haploid cells. In the present study, we report that the expression of a...

Cdk phosphorylation of the Ste11 transcription factor constrains differentiation-specific transcription to G1

Kjærulff, Søren, Andersen, Nicoline Resen, Borup, Mia Trolle, Nielsen, Olaf

Eukaryotic cells normally differentiate from G1; here we investigate the mechanism preventing expression of differentiation-specific genes outside G1. In fission yeast, induction of the transcription...