Dihydropyrimidine dehydrogenase pharmacogenetics in Caucasian subjects (1998)
Ridge, S.A., Sludden, J., Brown, O., Robertson, L., Wei, X., Sapone, A., ...
FMS mutations in myelodysplastic, leukemic, and normal subjects.
Ridge, S A, Worwood, M, Oscier, D, Jacobs, A, Padua, R A
The FMS gene encodes the functional cell surface receptor for colony-stimulating factor 1, the macrophage- and monocyte-specific growth factor. Codons 969 and 301 have been identified as potentially...
FMS mutations in myelodysplastic, leukemic, and normal subjects.
Ridge, S A, Worwood, M, Oscier, D, Jacobs, A, Padua, R A
The FMS gene encodes the functional cell surface receptor for colony-stimulating factor 1, the macrophage- and monocyte-specific growth factor. Codons 969 and 301 have been identified as potentially...
Mutations at codon 974 of the DPYD gene are a rare event.
Ridge, S. A., Brown, O., McMurrough, J., Fernandez-Salguero, P., Evans, W. E., Gonzalez, F. J., ...
A mutation at codon 974 of the dihydropyrimidine dehydrogenase (DPD) gene was previously described in a cancer patient with undetectable DPD enzyme activity who experienced severe toxicity when...
Dihydropyrimidine dehydrogenase pharmacogenetics in patients with colorectal cancer.
Ridge, S. A., Sludden, J., Wei, X., Sapone, A., Brown, O., Hardy, S., ...
Individuals with a deficiency in the enzyme dihydropyrimidine dehydrogenase (DPD) may experience severe life-threatening toxicity when treated with 5-fluorouracil (5-FU). As routine measurement of...