Basic biology and clinical application of specific cyclooxygenase-2 inhibitors (2000)
Crofford, L. J., Lipsky, P. E., Brooks, P. M., Abramson, S.B., Simon, L., Van De Putte, L. B.
The mode of action of aspirin-like drugs: effect on inducible nitric oxide synthase.
Amin, A R, Vyas, P, Attur, M, Leszczynska-Piziak, J, Patel, I R, Weissmann, G, ...
Nitric oxide synthesized by inducible nitric oxide synthase (iNOS) has been implicated as a mediator of inflammation in rheumatic and autoimmune diseases. We report that exposure of...
Clancy, R M, Levartovsky, D, Leszczynska-Piziak, J, Yegudin, J, Abramson, S B
We performed experiments to determine whether nitric oxide promoted the formation of intracellular S-nitrosothiol adducts in human neutrophils. At concentrations sufficient to inhibit...
Philips, M R, Buyon, J P, Winchester, R, Weissmann, G, Abramson, S B
The iC3b receptor (CR3) is required for neutrophil adhesive functions, including homotypic aggregation. Because stimuli that enhance neutrophil adhesion also induce up-regulation of surface CR3, it...
Clancy, R M, Leszczynska-Piziak, J, Abramson, S B
Nitric oxide provokes vasodilation and inhibits platelet aggregation. We examined the effect of nitric oxide on superoxide anion production by three sources: activated intact neutrophils, xanthine...
Circulating hydroxy fatty acids in familial Mediterranean fever.
Aisen, P S, Haines, K A, Given, W, Abramson, S B, Pras, M, Serhan, C, ...
Episodes of fever, serositis, and arthritis in familial Mediterranean fever (FMF) suggested circulating mediators of acute inflammation (e.g., neutrophil activation). The mean serum...
Amin, A R, Attur, M, Patel, R N, Thakker, G D, Marshall, P J, Rediske, J, ...
Cartilage specimens from osteoarthritis (OA)-affected patients spontaneously released PGE2 at 48 h in ex vivo culture at levels at least 50-fold higher than in normal cartilage and 18-fold higher...
Clancy, R M, Rediske, J, Tang, X, Nijher, N, Frenkel, S, Philips, M, ...
Elevated levels of fibronectin (Fn) in articular cartilage have been linked to the progression of both rheumatoid and osteoarthritis. In this study, we examined intracellular events which follow...
The mode of action of aspirin-like drugs: effect on inducible nitric oxide synthase.
Amin, A R, Vyas, P, Attur, M, Leszczynska-Piziak, J, Patel, I R, Weissmann, G, ...
Nitric oxide synthesized by inducible nitric oxide synthase (iNOS) has been implicated as a mediator of inflammation in rheumatic and autoimmune diseases. We report that exposure of...
Clancy, R M, Levartovsky, D, Leszczynska-Piziak, J, Yegudin, J, Abramson, S B
We performed experiments to determine whether nitric oxide promoted the formation of intracellular S-nitrosothiol adducts in human neutrophils. At concentrations sufficient to inhibit...
Philips, M R, Buyon, J P, Winchester, R, Weissmann, G, Abramson, S B
The iC3b receptor (CR3) is required for neutrophil adhesive functions, including homotypic aggregation. Because stimuli that enhance neutrophil adhesion also induce up-regulation of surface CR3, it...
Clancy, R M, Leszczynska-Piziak, J, Abramson, S B
Nitric oxide provokes vasodilation and inhibits platelet aggregation. We examined the effect of nitric oxide on superoxide anion production by three sources: activated intact neutrophils, xanthine...
Circulating hydroxy fatty acids in familial Mediterranean fever.
Aisen, P S, Haines, K A, Given, W, Abramson, S B, Pras, M, Serhan, C, ...
Episodes of fever, serositis, and arthritis in familial Mediterranean fever (FMF) suggested circulating mediators of acute inflammation (e.g., neutrophil activation). The mean serum...
Amin, A R, Attur, M, Patel, R N, Thakker, G D, Marshall, P J, Rediske, J, ...
Cartilage specimens from osteoarthritis (OA)-affected patients spontaneously released PGE2 at 48 h in ex vivo culture at levels at least 50-fold higher than in normal cartilage and 18-fold higher...
Clancy, R M, Rediske, J, Tang, X, Nijher, N, Frenkel, S, Philips, M, ...
Elevated levels of fibronectin (Fn) in articular cartilage have been linked to the progression of both rheumatoid and osteoarthritis. In this study, we examined intracellular events which follow...