O'ROURKE, JOHN F., WILSON, S. BRIAN
Isolated intact plant mitochondria, including those from turnip and mung bean, show low endogenous Mg2+-ATPase activity and, unlike mammalian mitochondria, lack significant uncoupler-stimulated...
GOONEWARDENA, HARRIS, WILSON, S. BRIAN
Washed and purified turnip mitochondria oxidize malate with respiratory control and ADP: O values approaching 3.0 and produce pyruvate as the principal product. Oxaloacetate is also produced in...
GOONEWARDENA, HARRIS, WILSON, S. BRIAN
The enzymes of malate oxidation in turnip mitochondria have been partially purified and some of their properties studied. Turnips contain a cytoplasmic malate dehydrogenase and two mito-chondrial...
GOONEWARDENA, HARRIS, WILSON, S. BRIAN
Oxaloacetic acid (OAA) and fluoro-oxaloacetic acid (FOAA) are both specific inhibitors of malate dehydrogenases. Exogenous OAA penetrates the mitochondria rapidly, being converted to pyruvate,...
Translocation of Some Anions, Cations, and Acids in Turnip (Brassica napus L.) Mitochondria (1977)
MOORE, ANTHONY L., WILSON, S. BRIAN
The translocation of various anions, cations, and acids across the membrane system of turnip mitchondria has been investigated by light scattering techniques. The results imply that the membranes of...
Wilson, S. Brian, Kent, Sally C., Horton, Heidi F., Hill, Andrew A., Bollyky, Paul L., Hafler, David A., ...
Quantitative and qualitative defects in CD1d-restricted T cells have been demonstrated in human and murine autoimmune diseases. To investigate the transcriptional consequences of T cell receptor...
Mandelboim, Ofer, Kent, Sally, Davis, Daniel M., Wilson, S. Brian, Okazaki, Taku, Jackson, Richard, ...
Proliferation of human CD4+ αβ T cells expressing a natural killer cell activating receptor (NKAR) has been shown to be enhanced, particularly in response to low doses of antigen, if the target...
Self and viral peptides can initiate lysis by autologous natural killer cells
Mandelboim, Ofer, Wilson, S. Brian, Valés-Gómez, Mar, Reyburn, Hugh T., Strominger, Jack L.
Natural killer (NK) cells are inhibited by specific allotypes of class I major histocompatibility complex ligands recognized by polymorphic inhibitory receptors (e.g., NKIR1 and NKIR2). NK1- and...
Heterophile antibodies segregate in families and are associated with protection from type 1 diabetes
She, Jin-Xiong, Ellis, Tamir M., Wilson, S. Brian, Wasserfall, Clive H., Marron, Michele, Reimsneider, Sharon, ...
Markedly elevated levels of serum IL-4 were reported previously in 50% of a small group of type 1 diabetes nonprogessors. To determine the patterns of expression for this phenotype, a larger cohort...
Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse
Shi, Fu-Dong, Flodström, Malin, Balasa, Balaji, Kim, Soon Ha, Van Gunst, Kurt, Strominger, Jack L., ...
Quantitative and qualitative defects in CD1-restricted natural killer T cells have been reported in several autoimmune-prone strains of mice, including the nonobese diabetic (NOD) mouse. These...
Naumov, Yuri N., Bahjat, Keith S., Gausling, Rudolph, Abraham, Roshini, Exley, Mark A., Koezuka, Yasuhiko, ...
CD1d-restricted invariant NKT (iNKT) cells are immunoregulatory cells whose loss exacerbates diabetes in nonobese diabetic (NOD) female mice. Here, we show that the relative numbers of iNKT cells...
CD1d and invariant NKT cells at the human maternal–fetal interface
Boyson, Jonathan E., Rybalov, Basya, Koopman, Louise A., Exley, Mark, Balk, Steven P., Racke, Frederick K., ...
Invariant CD1d-restricted natural killer T (iNKT) cells comprise a small, but significant, immunoregulatory T cell subset. Here, the presence of these cells and their CD1d ligand at the human...
Gillessen, Silke, Naumov, Yuri N., Nieuwenhuis, Edward E. S., Exley, Mark A., Lee, Frederick S., Mach, Nicolas, ...
CD1d-restricted T cells contribute to tumor protection, but their precise roles remain unclear. Here we show that tumor cells engineered to secrete granulocyte–macrophage colony-stimulating factor...
Wilson, S. Brian, Kent, Sally C., Horton, Heidi F., Hill, Andrew A., Bollyky, Paul L., Hafler, David A., ...
Quantitative and qualitative defects in CD1d-restricted T cells have been demonstrated in human and murine autoimmune diseases. To investigate the transcriptional consequences of T cell receptor...
Mandelboim, Ofer, Kent, Sally, Davis, Daniel M., Wilson, S. Brian, Okazaki, Taku, Jackson, Richard, ...
Proliferation of human CD4+ αβ T cells expressing a natural killer cell activating receptor (NKAR) has been shown to be enhanced, particularly in response to low doses of antigen, if the target...
Self and viral peptides can initiate lysis by autologous natural killer cells
Mandelboim, Ofer, Wilson, S. Brian, Valés-Gómez, Mar, Reyburn, Hugh T., Strominger, Jack L.
Natural killer (NK) cells are inhibited by specific allotypes of class I major histocompatibility complex ligands recognized by polymorphic inhibitory receptors (e.g., NKIR1 and NKIR2). NK1- and...
Heterophile antibodies segregate in families and are associated with protection from type 1 diabetes
She, Jin-Xiong, Ellis, Tamir M., Wilson, S. Brian, Wasserfall, Clive H., Marron, Michele, Reimsneider, Sharon, ...
Markedly elevated levels of serum IL-4 were reported previously in 50% of a small group of type 1 diabetes nonprogessors. To determine the patterns of expression for this phenotype, a larger cohort...
Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse
Shi, Fu-Dong, Flodström, Malin, Balasa, Balaji, Kim, Soon Ha, Van Gunst, Kurt, Strominger, Jack L., ...
Quantitative and qualitative defects in CD1-restricted natural killer T cells have been reported in several autoimmune-prone strains of mice, including the nonobese diabetic (NOD) mouse. These...
Naumov, Yuri N., Bahjat, Keith S., Gausling, Rudolph, Abraham, Roshini, Exley, Mark A., Koezuka, Yasuhiko, ...
CD1d-restricted invariant NKT (iNKT) cells are immunoregulatory cells whose loss exacerbates diabetes in nonobese diabetic (NOD) female mice. Here, we show that the relative numbers of iNKT cells...
CD1d and invariant NKT cells at the human maternal–fetal interface
Boyson, Jonathan E., Rybalov, Basya, Koopman, Louise A., Exley, Mark, Balk, Steven P., Racke, Frederick K., ...
Invariant CD1d-restricted natural killer T (iNKT) cells comprise a small, but significant, immunoregulatory T cell subset. Here, the presence of these cells and their CD1d ligand at the human...
Gillessen, Silke, Naumov, Yuri N., Nieuwenhuis, Edward E. S., Exley, Mark A., Lee, Frederick S., Mach, Nicolas, ...
CD1d-restricted T cells contribute to tumor protection, but their precise roles remain unclear. Here we show that tumor cells engineered to secrete granulocyte–macrophage colony-stimulating factor...
Hou, Runhua, Goloubeva, Olga, Neuberg, Donna S, Strominger, Jack L, Wilson, S Brian
Human invariant natural killer (iNK) T cells expressing an invariant Vα24-Jα15 T-cell receptor (TCR) are thought to be important regulators of autoimmunity and tumour surveillance. Two major...
Natural Killer T Cells Infiltrate Neuroblastomas Expressing the Chemokine CCL2
Metelitsa, Leonid S., Wu, Hong-Wei, Wang, Hong, Yang, Yujun, Warsi, Zamir, Asgharzadeh, Shahab, ...
CD1d-restricted Vα24-Jα18–invariant natural killer T cells (iNKTs) are potentially important in tumor immunity. However, little is known about their localization to tumors. We analyzed 98...
Montoya, Carlos J, Pollard, David, Martinson, Jeffrey, Kumari, Kumud, Wasserfall, Clive, Mulder, Candice B, ...
Identification of human CD1d-restricted T-cell receptor (TCR)-invariant natural killer T (iNKT) cells has been dependent on utilizing combinations of monoclonal antibodies or CD1d tetramers, which do...