Evaluation of the safety and immunogenicity of synthetic Aß42 (AN1792) in patients with AD (2005)
Bayer, A.J., Bullock, R., Jones, R.W., Wilkinson, D., Paterson, K.R., Jenkins, L., ...
Background: Aß42-immunization reduces plaque burden and improves cognition in transgenic mouse models of Alzheimer disease (AD). This phase 1 study evaluated the safety, tolerability, and...
Donoghue, S, Felder, R B, Gilbey, M P, Jordan, D, Spyer, K M
Post-synaptic responses evoked in neurones of the nucleus tractus solitarius by electrical stimulation of the carotid sinus, aortic and vagal nerves, alone or in combination, have been studied in...
Donoghue, S, Felder, R B, Jordan, D, Spyer, K M
The medullary projections of afferent neurons with cell bodies in the petrosal ganglion have been investigated using an antidromic mapping technique. Of the ninety-three units studied, fifty-eight...
Donoghue, S, Garcia, M, Jordan, D, Spyer, K M
1. The retrograde transport of horseradish peroxidase (HRP) was used to locate cell bodies of afferent neurones with axons in the aortic nerves within the nodose ganglia of cats and rabbits. 2. In...
The brain-stem projections of pulmonary stretch afferent neurones in cats and rabbits.
Donoghue, S, Garcia, M, Jordan, D, Spyer, K M
1. Micro-electrode recordings were made from slowly adapting pulmonary stretch afferents within the nodose ganglia of cats and rabbits. Recordings sites were distributed throughout the ganglia. 2....
Donoghue, S, Felder, R B, Gilbey, M P, Jordan, D, Spyer, K M
Post-synaptic responses evoked in neurones of the nucleus tractus solitarius by electrical stimulation of the carotid sinus, aortic and vagal nerves, alone or in combination, have been studied in...
Donoghue, S, Felder, R B, Jordan, D, Spyer, K M
The medullary projections of afferent neurons with cell bodies in the petrosal ganglion have been investigated using an antidromic mapping technique. Of the ninety-three units studied, fifty-eight...
Donoghue, S, Garcia, M, Jordan, D, Spyer, K M
1. The retrograde transport of horseradish peroxidase (HRP) was used to locate cell bodies of afferent neurones with axons in the aortic nerves within the nodose ganglia of cats and rabbits. 2. In...
The brain-stem projections of pulmonary stretch afferent neurones in cats and rabbits.
Donoghue, S, Garcia, M, Jordan, D, Spyer, K M
1. Micro-electrode recordings were made from slowly adapting pulmonary stretch afferents within the nodose ganglia of cats and rabbits. Recordings sites were distributed throughout the ganglia. 2....
Allan, G., Donoghue, S., Follenfant, M. J., Sawyer, D. A.
BW A256C (5(3)-amino-6-(2,3-dichlorophenyl)-2,3(2,5)-dihydro-3(5)-imino-2 -isopropyl-1,2,4-triazine) is a novel class 1 antiarrhythmic agent designed to combine the features of potency with reduced...
Jungmann, E., Mercey, D., DeRuiter, A., Edwards, S., Donoghue, S., Booth, T., ...
Objectives: To assess use of antiretroviral therapy (ART) by HIV positive pregnant women in London since 1994 and the risk of congenital abnormalities associated with multidrug exposure during the...