S. Frank Yan

In silicodiscovery of transcription regulatory elements in Plasmodium falciparum (2008)

Young, Jason A, Johnson, Jeffery R, Benner, Chris, Yan, S Frank, Chen, Kaisheng, Le Roch, Karine G, ...

Abstract Background With the sequence of the Plasmodium falciparum genome and several global mRNA and protein life cycle expression profiling projects now completed, elucidating the underlying...

Study of gene function based on spatial co-expression in a high-resolution mouse brain atlas (2007)

Liu, Zheng, Yan, S Frank, Walker, John R, Zwingman, Theresa A, Jiang, Tao, Li, Jing, ...

Abstract Background The Allen Brain Atlas (ABA) project systematically profiles three-dimensional high-resolution gene expression in postnatal mouse brains for thousands of genes. By unveiling gene...

Study of gene function based on spatial co-expression in a high-resolution mouse brain atlas. (2007)

Liu, Zheng, Yan, S Frank, Walker, John R, Zwingman, Theresa A, Jiang, Tao, Li, Jing, ...

BACKGROUND: The Allen Brain Atlas (ABA) project systematically profiles three-dimensional high-resolution gene expression in postnatal mouse brains for thousands of genes. By unveiling gene behaviors...

Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle (2004)

Le Roch, Karine G., Johnson, Jeffrey R., Florens, Laurence, Zhou, Yingyao, Santrosyan, Andrey, Grainger, Munira, ...

To investigate the role of post-transcriptional controls in the regulation of protein expression for the malaria parasite, Plasmodium falciparum, we have compared mRNA transcript and protein...

Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle

Le Roch, Karine G., Johnson, Jeffrey R., Florens, Laurence, Zhou, Yingyao, Santrosyan, Andrey, Grainger, Munira, ...

To investigate the role of post-transcriptional controls in the regulation of protein expression for the malaria parasite, Plasmodium falciparum, we have compared mRNA transcript and protein...

An efficient rapid system for profiling the cellular activities of molecular libraries

Melnick, Jonathan S., Janes, Jeff, Kim, Sungjoon, Chang, Jim Y., Sipes, Daniel G., Gunderson, Drew, ...

Rapid quantitative methods for characterizing small molecules, peptides, proteins, or RNAs in a broad array of cellular assays would allow one to discover new biological activities associated with...

Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle

Le Roch, Karine G., Johnson, Jeffrey R., Florens, Laurence, Zhou, Yingyao, Santrosyan, Andrey, Grainger, Munira, ...

To investigate the role of post-transcriptional controls in the regulation of protein expression for the malaria parasite, Plasmodium falciparum, we have compared mRNA transcript and protein...

An efficient rapid system for profiling the cellular activities of molecular libraries

Melnick, Jonathan S., Janes, Jeff, Kim, Sungjoon, Chang, Jim Y., Sipes, Daniel G., Gunderson, Drew, ...

Rapid quantitative methods for characterizing small molecules, peptides, proteins, or RNAs in a broad array of cellular assays would allow one to discover new biological activities associated with...

In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen

Plouffe, David, Brinker, Achim, McNamara, Case, Henson, Kerstin, Kato, Nobutaka, Kuhen, Kelli, ...

The growing resistance to current first-line antimalarial drugs represents a major health challenge. To facilitate the discovery of new antimalarials, we have implemented an efficient and robust...