Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.
Saxton, T M, Henkemeyer, M, Gasca, S, Shen, R, Rossi, D J, Shalaby, F, ...
Shp-1, Shp-2 and corkscrew comprise a small family of cytoplasmic tyrosine phosphatases that possess two tandem SH2 domains. To investigate the biological functions of Shp-2, a targeted mutation has...
A Large-Scale Gene-Trap Screen for Insertional Mutations in Developmentally Regulated Genes in Mice
Wurst, W., Rossant, J., Prideaux, V., Kownacka, M., Joyner, A., Hill, D. P., ...
We have used a gene-trap vector and mouse embryonic stem (ES) cells to screen for insertional mutations in genes developmentally regulated at 8.5 days of embryogenesis (dpc). From 38,730 cell lines...
Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.
Saxton, T M, Henkemeyer, M, Gasca, S, Shen, R, Rossi, D J, Shalaby, F, ...
Shp-1, Shp-2 and corkscrew comprise a small family of cytoplasmic tyrosine phosphatases that possess two tandem SH2 domains. To investigate the biological functions of Shp-2, a targeted mutation has...
A Large-Scale Gene-Trap Screen for Insertional Mutations in Developmentally Regulated Genes in Mice
Wurst, W., Rossant, J., Prideaux, V., Kownacka, M., Joyner, A., Hill, D. P., ...
We have used a gene-trap vector and mouse embryonic stem (ES) cells to screen for insertional mutations in genes developmentally regulated at 8.5 days of embryogenesis (dpc). From 38,730 cell lines...