S. Grimm

Publication List Details

Period

1991 - 2007

Number

49

Co-Authors

Nondestructive mechanical release of ordered polymer microfiber arrays from porous templates (2007)

Grimm, S., Schwirn, K., Göring, P., Knoll, H., Miclea, P.T., Greiner, A., ...

The fabrication of one-dimensional (1D) nanostructures and microstructures inside the pores of porous templates is intensively investigated. The release of these structures is commonly accomplished...

A.: Towards Ontologies for Formalizing Modularization and Communication in Large Software Systems (2006)

Daniel Oberle, Steffen Lamparter, S. Grimm, D. Vr, S. Staab, A. Gangemi

Large software systems are modularized in order to improve manageability. The parts of the software system communicate in order to achieve the desired functionality. To better understand, develop,...

Feature ontologies for the explicit representation of shape semantics (2005)

Brunetti, G., Grimm, S.

CAx systems typically encode the semantics of shapes as so-called parametric features on different levels of abstraction. Here we discuss an approach that combines feature-based parametric modelling...

Information management and knowledge sharing in WIDE (2004)

Smithers, T., Posada, J., Stork, A., Pianciamore, M., Ferreira, N., Grimm, S., ...

WIDE is an IST project whose aim is to investigate the use of emerging SemanticWeb technologies, tools, and standards in the support of effective knowledge sharing and information management in real...

A semantic approach for user depending information visualization (2004)

Burmeister, D., Grimm, S., Haist, J.

This paper intends to generalize given techniques in modeling semantic content according to the purpose of transferring them from industrial application scenarios to the requirements of design for...

A high-throughput screen for single gene activities: isolation of apoptosis inducers (2003)

Albayrak,T., Grimm,S.

We describe a novel genetic screen that is performed by transfecting every individual clone of an expression library into a separate population of cells in a high-throughput mode. The screen allows...

UBP41 is a proapoptotic ubiquitin-specific protease (2003)

Gewies,A., Grimm,S.

We have isolated Ubp41, a ubiquitin-specific protease, in a screen for proapoptotic genes. We found that overexpression of Ubp41 is sufficient to elicit all features of apoptosis in human cells. In...

Spike, a novel BH3-only protein, regulates apoptosis at the endoplasmic reticulum (2003)

Mund,T., Gewies,A., Schoenfeld,N., Bauer,M. K. A., Grimm,S.

We have isolated Spike, a novel and evolutionary conserved BH3- only protein. BH3-only proteins constitute a family of apoptosis inducers that mediate proapoptotic signals. In contrast to most...

UBP41 is a proapoptotic ubiquitin-specific protease (2003)

Gewies, A., Grimm, S.

We have isolated Ubp41, a ubiquitin-specific protease, in a screen for proapoptotic genes. We found that overexpression of Ubp41 is sufficient to elicit all features of apoptosis in human cells. In...

A high-throughput screen for single gene activities: isolation of apoptosis inducers (2003)

Albayrak, T., Grimm, S.

We describe a novel genetic screen that is performed by transfecting every individual clone of an expression library into a separate population of cells in a high-throughput mode. The screen allows...

Spike, a novel BH3-only protein, regulates apoptosis at the endoplasmic reticulum (2003)

Mund, T., Gewies, A., Schoenfeld, N., Bauer, M. K. A., Grimm, S.

We have isolated Spike, a novel and evolutionary conserved BH3- only protein. BH3-only proteins constitute a family of apoptosis inducers that mediate proapoptotic signals. In contrast to most...

Informations- und Wissensmanagement basierend auf Semantic Web Technologie (2003)

Grimm, S., Stork, A.

In diesem Beitrag wird das WIDE-Projekt als Lösungsansatz für eine bessere Zusammenarbeit unterschiedlicher Nutzergruppen, wie z.B. Designern und Ingenieuren, sowie als Wissensmanagement und...

Robotic high-throughput assay for isolating apoptosis-inducing genes (2002)

Grimm,S., Kachel,V.

The need to assign functions to genes will increase in upcoming years because of the accumulation of sequence information from various organisms. Here we present a genetic screen for the systematic...

The permeability transition pore signals apoptosis by directing Bax translocation and multimerization (2002)

De Giorgi,F., Lartigue,L., Bauer,M. K. A., Schubert,A., Grimm,S., Hanson,G. T., ...

Mitochondria are key players of apoptosis and can irreversibly commit the cell to death by releasing cytochrome c (Cyt.c) to the cytosol, where caspases 9 and 3 subsequently get activated. Under...

The permeability transition pore signals apoptosis by directing Bax translocation and multimerization (2002)

De Giorgi, F., Lartigue, L., Bauer, M. K. A., Schubert, A., Grimm, S., Hanson, G. T., ...

Mitochondria are key players of apoptosis and can irreversibly commit the cell to death by releasing cytochrome c (Cyt.c) to the cytosol, where caspases 9 and 3 subsequently get activated. Under...

Robotic high-throughput assay for isolating apoptosis-inducing genes (2002)

Grimm, S., Kachel, V.

The need to assign functions to genes will increase in upcoming years because of the accumulation of sequence information from various organisms. Here we present a genetic screen for the systematic...

Neutron fluence and dose measurements by optical fibers (1997)

Henschel, H., Köhn, O., Metzger, S., Decreton, M., Devos, P., Deparis, O., ...

It is shown that fibers doped with (Ge + P) or with (GE + B) can be used with good accuracy for fluence determinations of fast or slow neutrons, respectively, when they are calibrated at sources of...

RIP and FADD: two "death domain"-containing proteins can induce apoptosis by convergent, but dissociable, pathways.

Grimm, S, Stanger, B Z, Leder, P

With use of the yeast two-hybrid system, the proteins RIP and FADD/MORT1 have been shown to interact with the "death domain" of the Fas receptor. Both of these proteins induce apoptosis in mammalian...

Synthesis, deprotection, analysis and purification of RNA and ribozymes.

Wincott, F, DiRenzo, A, Shaffer, C, Grimm, S, Tracz, D, Workman, C, ...

Improvements in the synthesis, deprotection and purification of oligoribonucleotides are described. These advances allow for reduced synthesis and deprotection times, while improving product yield....

Functional antagonism between members of the myb family: B-myb inhibits v-myb-induced gene activation.

Foos, G, Grimm, S, Klempnauer, K H

The oncogene v-myb and its cellular progenitor c-myb encode nuclear, DNA binding phosphoproteins that control the expression of certain target genes in immature hematopoietic cells. Here, we report...

Participation of Colorado pediatricians and family physicians in the Medicaid program.

Berman, S, Wasserman, S, Grimm, S

The Pediatric Health Policy Group of the University of Colorado Health Sciences Center (Denver) surveyed 650 family physicians and 296 pediatricians in 1988, with 50% of family physicians and 48% of...

RIP and FADD: two "death domain"-containing proteins can induce apoptosis by convergent, but dissociable, pathways.

Grimm, S, Stanger, B Z, Leder, P

With use of the yeast two-hybrid system, the proteins RIP and FADD/MORT1 have been shown to interact with the "death domain" of the Fas receptor. Both of these proteins induce apoptosis in mammalian...

Synthesis, deprotection, analysis and purification of RNA and ribozymes.

Wincott, F, DiRenzo, A, Shaffer, C, Grimm, S, Tracz, D, Workman, C, ...

Improvements in the synthesis, deprotection and purification of oligoribonucleotides are described. These advances allow for reduced synthesis and deprotection times, while improving product yield....

Functional antagonism between members of the myb family: B-myb inhibits v-myb-induced gene activation.

Foos, G, Grimm, S, Klempnauer, K H

The oncogene v-myb and its cellular progenitor c-myb encode nuclear, DNA binding phosphoproteins that control the expression of certain target genes in immature hematopoietic cells. Here, we report...

Participation of Colorado pediatricians and family physicians in the Medicaid program.

Berman, S., Wasserman, S., Grimm, S.

The Pediatric Health Policy Group of the University of Colorado Health Sciences Center (Denver) surveyed 650 family physicians and 296 pediatricians in 1988, with 50% of family physicians and 48% of...