S. H.

A nitric oxide signalling pathway controls CREB-mediated gene expression in neurons (2006)

• Riccio,
• A.,
• Alvania,
• R.,
• Lonze,
• B.E.,
• ...

Mould and Winter Indoor Relative Humidity in Low Income Households in England. (2006)

• Oreszczyn,
• T.,
• Ridley,
• I.,
• Wilkinson,
• P.,
• ...

Mechanisms of dysregulation of low-density lipoprotein receptor expression in vascular smooth muscle cells by inflammatory cytokines. (2006)

• Ruan,
• X.Z.,
• Moorhead,
• J.F.,
• Tao,
• J.L.,
• ...

Psychobiological reactivity, physical activity, and cardiovascular health. (2006)

• Boutcher,
• S.H.,
• Hamer,
• M.

Impact of moderate overweight and body composition on postexercise hemodynamic responses in healthy men (2006)

• Hamer,
• M.,
• Boutcher,
• S.H.

Reproducibility of skeletal muscle vasodilatation responses to stroop mental challenge over repeated sessions (2006)

• Hamer,
• M.,
• Boutcher,
• Y.N.,
• Park,
• Y.,
• ...

Glutathione and the redox control system trypanothione/trypanothione reductase are involved in the protection of Leishmania spp. against nitrosothiol-induced cytotoxicity. (2006)

• Romao,
• P.R.,
• Tovar,
• J.,
• Fonseca,
• S.G.,
• ...

Medicina y Patolog¡a Oral (2006)

• Bag n,
• J.-V.,
• Scully,
• C.,
• Urizar,
• J.M.A.,
• ...

Utilization of petroleum hydrocarbons by Pseudomonas   sp. and transformed Escherichia coli   (2005)

• Emtiazi,
• G.,
• Shakarami,
• H.,
• Nahvi,
• I.,
• ...

Our previous studies showed that the biodegradation of petroleum oil by a pseudomonas isolated from a petroleum-contaminated soil was instable. In this work, it is shown that when the isolates are...

VIRTUAL DE-MANUFACTURING VIA VIRTUAL DISASSEMBLY TO DESIGN ENVIRONMENTALLY CONSCIOUS PRODUCTS. (R825370C067) (2005)

• Shyamsundar,
• N.,
• S H.,
• R And

The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the...

Circulating angiotensin converting enzyme activity is correlated with muscle strength (2005)

• Williams,
• A.G.,
• Day,
• S.H.,
• Folland,
• J.P.,
• ...

PURPOSE: The D-variant of the angiotensin-1 converting enzyme (ACE) gene is associated with higher circulating and tissue ACE activity. Some studies have suggested a similar association of genotype...

Expression of FGFR-2 and FGFR-3 in the normal human fetal orbit (2005)

• Khan,
• S.H.,
• Britto,
• J.A.,
• Evans,
• R.D.,
• ...

Aims: To demonstrate the expression patterns of two fibroblast growth factor receptors (FGFR-2 and FGFR-3) in the normal human fetal orbit. Methods: 6 mm orbital slide sections were prepared from 12...

Protein conformation significantly influences immune responses to prion protein (2005)

• Khalili-Shirazi,
• A.,
• Quaratino,
• S.,
• Londei,
• M.,
• ...

In prion diseases, such as variant Creutzfeldt-Jakob disease normal cellular prion protein (PrPC), a largely alpha-helical structure is converted to an abnormal conformational isoform (PrPSc) that...

Effects of sirolimus on mesangial cell cholesterol homeostasis: a novel mechanism for its action against lipid-mediated injury in renal allografts. (2005)

• Varghese,
• Z.,
• Fernando,
• R.,
• Moorhead,
• J.F.,
• ...

Origins and properties of Mycobacterium tuberculosis isolates in London (2005)

• Dale,
• J.W.,
• Bothamley,
• G.H.,
• Drobniewski,
• F.,
• ...

Using similarities of IS6110 banding patterns, isolates of Mycobacterium tuberculosis from a population-based study in London were assigned to 12 large groups termed ?superfamilies? (sfams). Analysis...

Effect of pedal rate and power output on ratings of perceived exertion during cycle ergometry exercise (2005)

• Hamer,
• M.,
• Boutcher,
• Y.N.,
• Boutcher,
• S.H.

Stress-reactivity and health - the impact of exercise and nutrition (2005)

• Hamer,
• M.,
• Boutcher,
• S.H.

Heritability of macular pigment: a twin study (2005)

• Liew,
• S.H.,
• Gilbert,
• C.E.,
• Spector,
• T.D.,
• ...

PURPOSE: Several studies have reported higher levels of macular pigment (MP) in association with reduced risk for age-related macular degeneration (ARMD), a disease to which there is a genetic...

ω3 polyunsaturated fatty acids decrease LPS stimulated NF-kappa B activity in HK-2 cell: evidence for a PPAR gammar dependent mechanism (2005)

• Li,
• H.,
• Ruan,
• X.Z.,
• Moorhead,
• J.F.,
• ...

Recent studies have shown that fish oil, containing ω-3 polyunsaturated fatty acids (ω-3 PUFAs) eicosapentaenoic acid (EPA, C20:5 ω 3) and docosahexaenoic acid (DHA, C22:6 ω 3)...

Ethylmalonic encephalopathy is caused by mutations in ETHE1, a gene encoding a mitochondrial matrix protein (2004)

• Tiranti,
• V.,
• D'Adamo,
• P.,
• Briem,
• E.,
• ...

Ethylmalonic encephalopathy (EE) is a devastating infantile metabolic disorder affecting the brain, gastrointestinal tract, and peripheral vessels. High levels of ethylmalonic acid are detected in...

Tolerance and safety of different concentrations of chlorhexidine for peripartum vaginal and infant washes: HIVNET 025. (2004)

• Wilson,
• C.M.,
• Gray,
• G.,
• Read,
• J.S.,
• ...

A pilot randomised controlled study of three models of follow-up of patients treated for gynaecological cancer: attitudes in general practice and feasibility of randomisation (2004)

• Moses,
• S.H.,
• Olaitan,
• A.,
• Murdoch,
• J.B.,
• ...

A bradykinin receptor gene variant and human physical performance (2004)

• Williams,
• A.G.,
• Dhamrait,
• S.,
• Wootton,
• P.T.,
• ...

Alpha-fetoprotein impairs APC function and induces their apoptosis. (2004)

• Um,
• S.H.,
• Mulhall,
• C.,
• Alisa,
• A.,
• ...

Evolutionary relationships among strains of Mycobacterium tuberculosis with few copies of IS6110 (2003)

• Dale,
• J.W.,
• Al Ghusein,
• H.,
• Butcher,
• P.,
• ...

Fluoroquinolone resistance in Streptococcus pneumoniae: evidence that gyrA mutations arise at a lower rate and that mutation in gyrA or parC predisposes to further mutation (2003)

• Gillespie,
• S.H.,
• Voelker,
• L.L.,
• Ambler,
• J.E.,
• ...

A reiterative method for calculating bactericidal activity (2003)

• Mitchison,
• D.A.,
• Gillespie,
• S.H.,
• Charalambous,
• B.M.,
• ...

Bactericidal activity of antituberculosis drugs (2003)

• Doré,
• C.J.,
• Nunn,
• A.J.,
• Gillespie,
• S.H.,
• ...

Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. (2003)

• Segurado,
• R.,
• Detera-Wadleigh,
• S.D.,
• Levinson,
• D.F.,
• ...

Genome scans of bipolar disorder (BPD) have not produced consistent evidence for linkage. The rank-based genome scan meta-analysis (GSMA) method was applied to 18 BPD genome scan data sets in an...

Human immunodeficiency virus type 1-related pulmonary Mycobacterium xenopi infection: a need to treat? (2003)

• Kerbiriou,
• L.,
• Ustianowski,
• A.,
• Johnson,
• M.A.,
• ...

We report treatment decisions and outcomes for 20 patients who were infected with human immunodeficiency virus type 1 (HIV-1) and were receiving highly active antiretroviral therapy (HAART) who had...

Impact of azithromycin administration for trachoma control on the carriage of antibiotic-resistant Streptococcus pneumoniae (2003)

• Batt,
• S.L.,
• Charalambous,
• B.M.,
• Solomon,
• A.W.,
• ...

Molecular methods for Mycobacterium tuberculosis strain typing: a users guide (2003)

• Kanduma,
• E.,
• McHugh,
• T.D.,
• Gillespie,
• S.H.

Severe acute respiratory syndrome (SARS): breath-taking progress (2003)

• Hawkey,
• P.M.,
• Bhagani,
• S.,
• Gillespie,
• S.H.

The bactericidal activity of moxifloxacin in patients with pulmonary tuberculosis (2003)

• Gosling,
• R.D.,
• Uiso,
• L.O.,
• Sam,
• N.E.,
• ...

Visual outcomes and amblyogenic risk factors in craniosynostotic syndromes: a review of 141 cases (2003)

• Khan,
• S.H.,
• Nischal,
• K.K.,
• Dean,
• F.,
• ...

AIMS: To determine the visual outcome and prevalence of amblyogenic risk factors in children with craniosynostotic syndromes. METHODS: The case notes of 141 children seen within the craniofacial unit...

PPAR agonists protect mesangial cells from interleukin 1beta-induced intracellular lipid accumulation by activating the ABCA1 cholesterol efflux pathway (2003)

• Ruan,
• X.Z.,
• Moorhead,
• J.F.,
• Fernando,
• R.,
• ...

Previous studies have demonstrated that inflammatory cytokines such as interleukin-1beta (IL-1beta) promote lipid accumulation in human mesangial cells (HMC) by dysregulating the expression of...

Coalescence and inflection properties of Coulomb wavefunctions (2002)

• Patil,
• S. H.

We discuss some pedagogically useful properties of the energy eigenfunctions for the Coulomb potential, in particular the coalescence property when the particle is close to the origin, and the...

Wavefunctions for the confined hydrogen atom based on coalescence and inflexion properties (2002)

• Patil,
• S. H.

The energy eigenfunctions of a confined hydrogen atom have a simple coalescence property near the centre, and an inflexion property at the boundary and nodal points. Using these properties, simple...

Evolutionary barriers to quinolone resistance in Streptococcus pneumoniae (2002)

• Gillespie,
• S.H.,
• Voelker,
• L.L.,
• Dickens,
• A.

It is assumed that bacteria always pay a significant physiological price for the acquisition of resistance to antibiotics. To test whether this was the case for a strain of Streptococcus pneumoniae...

Molecular epidemiology of tuberculosis in London 1995-7 showing low rate of active transmission (2002)

• Maguire,
• H.,
• Dale,
• J.W.,
• McHugh,
• T.D.,
• ...

BACKGROUND: Tuberculosis notification rates for London have risen dramatically in recent years. Molecular typing of Mycobacterium tuberculosis has contributed to our understanding of the epidemiology...

Carotid intima-media thickness is associated with allelic variants of stromelysin-1, interleukin-6, and hepatic lipase genes: the Northern Manhattan Prospective Cohort Study (2002)

• Rundek,
• T.,
• Elkind,
• M.S.,
• Pittman,
• J.,
• ...

BACKGROUND AND PURPOSE: Atherosclerosis is a complex disorder with hereditary and environmental causes. Carotid artery intima-media wall thickness (IMT) is a useful measure of atherosclerosis. The...

A reiterative method for calculating the early bactericidal activity of antituberculosis drugs (2002)

• Gillespie,
• S.H.,
• Gosling,
• R.D.,
• Charalambous,
• B.M.

Studies of early bactericidal activity (EBA) are important in the rapid evaluation of new antituberculosis drugs. Historically, these have concentrated on the log fall in the viable count in sputum...

Evolution of drug resistance in Mycobacterium tuberculosis: clinical and molecular perspective (2002)

• Gillespie,
• S.H.

Examination of the rate of unrecognized cross-contamination with Mycobacterium tuberculosis in London microbiology laboratories (2002)

• Ruddy,
• M.,
• McHugh,
• T.D.,
• Dale,
• J.W.,
• ...

Microbes sans frontieres (2002)

• Gillespie,
• S.H.

Migrating worms (2002)

• Gillespie,
• S.H.

Multiple drug resistant tuberculosis: evidence for changing fitness on passage through human hosts (2002)

• Gillespie,
• S.H.,
• Billington,
• O.J.,
• Breathnach,
• A.,
• ...

New quinolones for respiratory infections: mechanisms of action and resistance (2002)

• Gillespie,
• S.H.

Novel perspectives in antibacterial action (2002)

• Gillespie,
• S.H.,
• Tillotson,
• G.S.

Purification of native -enolase from Streptococcus pneumoniae that binds plasminogen and is immunogenic (2002)

• Whiting,
• G.C.,
• Evans,
• J.T.,
• Patel,
• S.,
• ...

Functional magnetic resonance imaging of odor identification: the effect of aging. (2001)

• Suzuki,
• Y.,
• Critchley,
• H.D.,
• Suckling,
• J.,
• ...

Comparison of variable number tandem repeat and IS6110-restriction fragment length polymorphism analyses for discrimination of high- and low-copy-number IS6110 Mycobacterium tuberculosis isolates (2001)

• Barlow,
• R.E.,
• Gascoyne-Binzi,
• D.M.,
• Gillespie,
• S.H.,
• ...

Not available

Differential vulnerability of basal and apical hair cells is based on intrinsic susceptibility to free radicals (2001)

• Sha,
• S.H.,
• Taylor,
• R.,
• Forge,
• A.,
• ...

Susceptibility of the porcine endogenous retrovirus to reverse transcriptase and protease inhibitors (2001)

• Qari,
• S.H.,
• Magre,
• S.,
• Garcia-Lerma,
• J.G.,
• ...

Porcine xenografts may offer a solution to the shortage of human donor allografts. However, all pigs contain the porcine endogenous retrovirus (PERV), raising concerns regarding the transmission of...

False molecular clusters due to non-random association of IS6110 with Mycobacterium tuberculosis (2000)

• Gillespie,
• S.H.,
• Dickens,
• A.,
• McHugh,
• T.D.

Reduced heparan sulphate accumulaton in enterocytes contributes to protein losing enteropathy in a congenital disorder of glycosylation (2000)

• Westphal,
• V.,
• Murch,
• S.H.,
• Soohyun,
• K.,
• ...

intestinal biopsy in a boy with gastroenteritis-induced protein-losing enteropathy (PLE) showed loss of heparan sulfate (HS) and syndecan-1 core protein from the basolateral surface of the...

Identification of new genes within the MHC susceptibility region for psoriasis (2000)

• Goldsworthy,
• M.,
• Balendran,
• N.,
• Barker,
• J.N.W.N.,
• ...

Psoriasis susceptibility: Characterization of potential new candidate genes (2000)

• Balendran,
• N.,
• Goldsworthy,
• M.,
• Barker,
• J.N.W.N.,
• ...

Autoimmune enteropathy with distinct mucosal features in T-cell activation deficiency: the contribution of T cells to the mucosal lesion (1999)

• Murch,
• S.H.,
• Fertleman,
• C.R.,
• Rodrigues,
• C.,
• ...