Formation and characterization of FeLV iscoms. (1989)
Akerblom, L., Strömstedt, K., Höglund, S., Osterhaus, A.D.M.E., Morein, B.
Immunostimulating complexes (ISCOMs) have been prepared from feline leukaemia virus (FeLV) envelope proteins. The ISCOMs were characterized biochemically in SDS-polyacrylamide gel electrophoresis...
Iscoms and immunostimulation with viral antigens. (1989)
Höglund, S., Dalsgaard, K., Lövgren, K., Sundquist, B., Osterhaus, A.D.M.E., Morein, B.
Morein, B., Sundquist, B., Höglund, S., Dalsgaard, K., Osterhaus, A.D.M.E.
We describe here a novel type of immunostimulating complex, called 'iscom', in which virus membrane proteins are presented in a multimeric form. The matrix of the iscom is the glycoside Quil A...
Humphrey, R W, Ohagen, A, Davis, D A, Fukazawa, T, Hayashi, H, Höglund, S, ...
The processing of gag and gag-pol polyproteins by human immunodeficiency virus type 1 (HIV-1) protease is a crucial step in the formation of infectious HIV-1 virions. In this study, we examine...
Berkowitz, R D, Ohagen, A, Höglund, S, Goff, S P
The retroviral nucleocapsid (NC) protein is necessary for the specific encapsidation of the viral genomic RNA by the assembling virion. However, it is unclear whether NC contains the determinants for...
Role of the major homology region of human immunodeficiency virus type 1 in virion morphogenesis.
Mammano, F, Ohagen, A, Höglund, S, Göttlinger, H G
Retroviral capsid (CA) proteins contain a uniquely conserved stretch of 20 amino acids which has been named the major homology region (MHR). To examine the role of this region in human...
Functional domains of the capsid protein of human immunodeficiency virus type 1.
Dorfman, T, Bukovsky, A, Ohagen, A, Höglund, S, Göttlinger, H G
A series of deletions was introduced into the CA domain of the human immunodeficiency virus type 1 Gag polyprotein to examine its role in virus particle and core formation. The mutations resulted in...
Morein, B., Höglund, S., Bergman, R.
The antigenicity of two parainfluenza=3 virus strains, a “neuraminidasestrong” and a “neuraminidase-weak,” was compared. For both strains the amount of hemagglutinin units was equal. The...
Macpherson, E, Tomkinson, B, Bålöw, R M, Höglund, S, Zetterqvist, O
Tripeptidyl peptidase II is an extralysosomal serine peptidase of an unusually large size, i.e. Mr greater than 10(6) for the native enzyme and Mr 135000 for the subunit. The enzyme from human...
Sandberg, H, Andersson, L O, Höglund, S
Lipid-protein particles with platelet factor 3 measured by the Stypven clotting-time test [Hardisty & Hutton (1966) Br. J. Haematol. 12, 764-776] have been isolated from platelet-release supernatant....
Humphrey, R W, Ohagen, A, Davis, D A, Fukazawa, T, Hayashi, H, Höglund, S, ...
The processing of gag and gag-pol polyproteins by human immunodeficiency virus type 1 (HIV-1) protease is a crucial step in the formation of infectious HIV-1 virions. In this study, we examine...
Berkowitz, R D, Ohagen, A, Höglund, S, Goff, S P
The retroviral nucleocapsid (NC) protein is necessary for the specific encapsidation of the viral genomic RNA by the assembling virion. However, it is unclear whether NC contains the determinants for...
Role of the major homology region of human immunodeficiency virus type 1 in virion morphogenesis.
Mammano, F, Ohagen, A, Höglund, S, Göttlinger, H G
Retroviral capsid (CA) proteins contain a uniquely conserved stretch of 20 amino acids which has been named the major homology region (MHR). To examine the role of this region in human...
Functional domains of the capsid protein of human immunodeficiency virus type 1.
Dorfman, T, Bukovsky, A, Ohagen, A, Höglund, S, Göttlinger, H G
A series of deletions was introduced into the CA domain of the human immunodeficiency virus type 1 Gag polyprotein to examine its role in virus particle and core formation. The mutations resulted in...
Morein, B., Höglund, S., Bergman, R.
The antigenicity of two parainfluenza=3 virus strains, a “neuraminidasestrong” and a “neuraminidase-weak,” was compared. For both strains the amount of hemagglutinin units was equal. The...
Macpherson, E, Tomkinson, B, Bålöw, R M, Höglund, S, Zetterqvist, O
Tripeptidyl peptidase II is an extralysosomal serine peptidase of an unusually large size, i.e. Mr greater than 10(6) for the native enzyme and Mr 135000 for the subunit. The enzyme from human...
Sandberg, H, Andersson, L O, Höglund, S
Lipid-protein particles with platelet factor 3 measured by the Stypven clotting-time test [Hardisty & Hutton (1966) Br. J. Haematol. 12, 764-776] have been isolated from platelet-release supernatant....