A new approach for volumetric assessment of left ventricular function with MDCT (2006)
S Yamamoto, S Hamada, M Miyamoto, J Masumoto, K Komizu, L Linuma, ...
Spectroscopic study of the unbound 11N nucleus (2003)
Guimarães,V., Kubono,S., Barker,F. C., Hosaka,M., Jeong,S. C., Katayama,I., ...
The nuclear structure of the unbound 11N nucleus has been investigated by the 14N(³He,6He)11N reaction. The energies and widths of the observed states are compared with other measurements. Angular...
Influence of surface roughness on the charging of insulating spacers in vacuum (2001)
Yamamoto, O, Takuma, T, Hamada, S, Kakehashi, Y, Ikoma, S, Nisimura, K, ...
Bogdanski, M, Emura, T, Ganguli, S N, Gurtu, A, Hamada, S, Hamatsu, R, ...
Particle Impact Damage in Silicon Carbide. (1998)
Suzuki, A., Natsumura, T., Sugiyama, S., Teramae, T., Hamada, S.
The impact damage that occurred in silicon carbide plates was investigated by projectile impact tests. Target plates of silicon carbide with two different thicknesses were impacted by three kinds of...
Structure of light proton-rich nuclei on the drip-line (1995)
Guimarães, V, Kubono, S, Hosaka, M, Ikeda, N, Jeong, S C, Katayama, I, ...
仔馬のパラチフス症に關する研究 : III. 馬流産菌に對する仔馬の血清反應に就いて (1953)
Investigation was conducted to learn the transference of antibodies from mare to foal. At the same time, investigation was made on how antibodies develop in foals infected naturally or artificially...
鷄のサルモネラ症に關する研究 : I. 死籠卵及び斃死初生雛の細菌學的觀察 (1953)
小野, 悌二, 加藤, 英一, 黎, 憲祖, 濱田, 輔一, 平戸, 勝七, 福見, 秀雄, ...
In May and June 1951,the present authors carried out bacteriological examinations on dead-in-shell-chicks, chicks died before first feeding and brooding chicks at hatching plants and breeding plants...
仔馬のパラチフス症に關する研究 : II. 幼駒に於けるパラチフスの爆發的流行例に就て (1953)
At Horoizumi village in Hidaka district, Hokkaido, paratyphoid broke out in horses of all ages during several months following January, 1944. In this endemic, 33 out of 48 1-year-old foals had...
Kontani, M, Ono, H, Shibata, H, Okamura, Y, Tanaka, T, Fujiwara, T, ...
It has been shown that Porphyromonas gingivalis 381, a suspected periodontopathogen, possesses fimbriae on its cell surface. The organism is also known to produce proteases which can degrade the host...
Takahashi, I, Kiyono, H, Jackson, R J, Fujihashi, K, Staats, H F, Hamada, S, ...
Linear B- and T-cell epitopes spanning all 103 amino acids of the Escherichia coli heat-labile toxin B subunit (LT-B) were assessed in mice orally immunized with native LT or with recombinant...
Iki, K, Kawahara, K, Sawamura, S, Arakaki, R, Sakuta, T, Sugiyama, A, ...
A novel immunobiologically active fraction was prepared from a phenol-water extract of Prevotella intermedia ATCC 25611 by Sephadex G-100 column chromatography. The fraction consisted mainly of...
Ohta, K, Hamada, S, Nakamura, T
Pure nonhydrolyzed inulin was directly converted to ethanol in a simultaneous saccharification and fermentation process. An inulinase-hyperproducing mutant, Aspergillus niger 817, was grown in a...
Inhibitory effect of oolong tea polyphenols on glycosyltransferases of mutans Streptococci.
Nakahara, K, Kawabata, S, Ono, H, Ogura, K, Tanaka, T, Ooshima, T, ...
Oolong tea extract (OTE) was found to inhibit the water-insoluble glucan-synthesizing enzyme, glucosyltransferase I (GTase-I), of Streptococcus sobrinus 6715. The GTase-inhibitory substance in the...
Takahashi, I, Okahashi, N, Hamada, S
Mutans streptococci have been shown to give rise to variants in terms of expression of surface protein antigens by repeated subculturing of the organisms, which in turn induces changes in colonial...
Plasmid specifying total degradation of 3-chlorobenzoate by a modified ortho pathway.
Chatterjee, D K, Kellogg, S T, Hamada, S, Chakrabarty, A M
A plasmid, termed pAC25, specifying biodegradation of 3-chlorobenzoate in a strain of Pseudomonas putida has been characterized. During growth of the plasmid-harboring cells with 3-chlorobenzoate,...
Smouldering epidemic of Yersinia pseudotuberculosis in barn rats.
Kaneko, K I, Hamada, S, Kasai, Y, Hashimoto, N
Yersinia pseudotuberculosis was isolated from 8 (8 Rattus norvegicus) of 270 (259 R. norvegicus and 11 R. rattus) rats examined. Seasonal variation was not found in the incidence of isolations. The...
Takada, H, Mihara, J, Morisaki, I, Hamada, S
Normal human gingival fibroblasts stimulated in vitro by lipopolysaccharides (LPS) from oral Bacteroides species produced cell-free and cell-associated thymocyte-activating factors (TAF)....
Ogawa, T, Uchida, H, Kusumoto, Y, Mori, Y, Yamamura, Y, Hamada, S
We detected and quantified tumor necrosis factor alpha (TNF-alpha) and interleukin-6 (IL-6) from monocytes/macrophages (M phi) in the peripheral blood of subjects from three different population...
Ogawa, T, Kuribayashi, S, Shimauchi, H, Toda, T, Hamada, S
Outer membrane proteins (OMP) of Porphyromonas endodontalis HG 370 (ATCC 35406) were prepared from the cell envelope fraction of the organisms. The cell envelope that had been obtained by sonication...
Hamada, S, Horikoshi, T, Minami, T, Kawabata, S, Hiraoka, J, Fujiwara, T, ...
The effect of polyclonal egg yolk immunoglobulin G antibodies (yIgG) raised against whole cells, cell-free (CF) glucosyltransferase (GTase), or cell-associated (CA) GTase of serotype c Streptococcus...
Nishihara, T, Koga, T, Hamada, S
Lipopolysaccharide (LPS) was extracted from whole cells of Haemophilus actinomycetemcomitans Y4 by the hot phenol-water procedure. LPS was cleaved into its lipid A and polysaccharide moieties by...
Nishihara, T, Koga, T, Hamada, S
Murine macrophages of the P388D1 cell line stimulated with lipopolysaccharide (LPS) from Haemophilus actinomycetemcomitans Y4 released an interleukin-1 (IL-1) inhibitor, as well as IL-1. Maximal IL-1...
Ogawa, T, Shimauchi, H, Hamada, S
A 41,000-molecular-weight fimbrial protein was isolated from freshly cultivated whole cells of Bacteroides gingivalis 381 and purified chromatographically. Salivary and serum antibody responses to...
Koga, T, Nishihara, T, Fujiwara, T, Nisizawa, T, Okahashi, N, Noguchi, T, ...
Lipopolysaccharides (LPSs) were isolated from Bacteroides gingivalis and Escherichia coli by the phenol-water and butanol-water procedures. The phenol-water-extracted LPS from B. gingivalis 381 was...
Okahashi, N, Asakawa, H, Koga, T, Masuda, N, Hamada, S
Streptococcus mutans MT6801 , MT6861 , and MT6879 , which form large mucoid colonies on mitis salivarius agar, were isolated from a mother and her two daughters. These isolates were identified as...
Koga, T, Okahashi, N, Yamamoto, T, Mizuno, J, Inoue, M, Hamada, S
Cell wall carbohydrate antigen of Streptococcus sanguis ATCC 10557 (serotype II/biotype B) was extracted from purified cell walls by treatment with 5% trichloroacetic acid at 4 degrees C for 8 h. The...
Production of monoclonal antibody against a glucosyltransferase of Streptococcus mutans 6715.
Furuta, T, Nisizawa, T, Chiba, J, Hamada, S
A mouse hybrid cell line secreted monoclonal antibody which reacted specifically with Streptococcus mutans 6715 (serotype g) glucosyltransferase (GTase)-synthesizing water-insoluble glucan and...
Morisaki, I, Michalek, S M, Harmon, C C, Torii, M, Hamada, S, McGhee, J R
In the present study, we compared the ability of the soluble adjuvants concanavalin A (ConA), muramyl dipeptide (MDP), and peptidoglycan (PG) to enhance immune responses to orally administered...
Todome, Y, Ohkuni, H, Yokomuro, K, Kimura, Y, Hamada, S, Johnston, K H, ...
We describe the measurement by enzyme-linked immunosorbent assay of antibody to group A Streptococcus C carbohydrate in immunized rabbits and human sera, with trypsin-pronase-treated group A...
Longitudinal survey of the distribution of various serotypes of Streptococcus mutans in infants.
Masuda, N, Tsutsumi, N, Sobue, S, Hamada, S
The establishment of various serotypes of Streptococcus mutans was studied serologically in plaque samples collected from label surfaces of upper primary incisors of 22 infants (starting age, 5 to 13...
Isolation and serotyping of Streptococcus mutans from teeth and feces of children.
Hamada, S, Masuda, N, Kotani, S
Streptococcus mutans were detected in the feces from 10 of 29 caries-active patients, aged 4 to 9 years. The percentage of S. mutans to the total counts of facultatively anaerobic streptococci on...
Isolation and immunobiological classification of Streptococcus sanguis from human tooth surfaces.
Hamada, S, Torii, M, Tsuchitani, Y, Kotani, S
A total of 113 pure cultures of Streptococcus sanguis were obtained from dental plaque samples of 64 subjects. All isolates synthesized glucan from sucrose, elaborated peroxide, and were...
Occurrence of Yersinia enterocolitica in house rats.
Kaneko, K I, Hamada, S, Kasai, Y, Kato, E
From July 1976 to May 1977, 270 rats (259 Rattus norvegicus and R. rattus) in Sapporo were examined for the presence of Yersinia enterocolitica in house rats. The organism was isolated in 55 rats (54...
Porphyromonas gingivalis 381 fimbriae, their synthetic peptide segments, and lipopolysaccharide (LPS) were examined for hemagglutinating and migration-stimulating activities. P. gingivalis 381...
Koga, T, Hamada, S, Murakawa, S, Endo, A
The effects of mutastein, a glucosyltransferase inhibitor derived from an Aspergillus terreus strain, on the glucan synthesis by glucosyltransferases of Streptococcus mutans and sucrose-dependent...
Non-cariogenicity of the disaccharide palatinose in experimental dental caries of rats.
Ooshima, T, Izumitani, A, Sobue, S, Okahashi, N, Hamada, S
The caries-inducing activity of palatinose (isomaltulose, alpha-D-glucopyranosyl-1,6-fructose) was examined in in vitro and in vivo experiments, comparing it with other carbohydrates. When...
Okahashi, N, Koga, T, Akada, H, Hamada, S
The serotype-specific antigen of Streptococcus sanguis ST3 (serotype I, biotype A) was extracted, chromatographically purified, and characterized by immunological and chemical methods. The antigen...
Michalek, S M, Morisaki, I, Harmon, C C, Hamada, S, McGhee, J R
Gnotobiotic rats were given Streptococcus mutans 6715 whole cells (WC), purified cell walls (CW), or cell wall lysate by gastric intubation (GI), and assessments were made of humoral immune responses...
Hamada, S, Torii, M, Kotani, S, Tsuchitani, Y
Streptococcus sanguis isolated from human dental plaque were grown in Todd-Hewitt broth. Cells were collected by centrifugation and lyophilized after extensive washing with water. The cell-associated...
Hamada, S, Mizuno, J, Murayama, Y, Ooshima, Y, Masuda, N
A dextranase preparation (AD17) partially purified from a culture liquor of Spicaria violacea strain IFO 6120 significantly inhibited the formation of artifcial dental plaque on a steel wire or on an...
Hot saline extracts of Streptococcus mutans have been shown to contain antigenic substances which occasionally react nonspecifically with some antisera against whole cells of various serological...
The type-specific antigen of Streptococcus mutans strain MT703, serotype e, has been chromatographically purified and characterized. Two chromatographic fractions were obtained from saline extracts...
Chemical and immunological properties of the type f polysaccharide antigen of Streptococcus mutans.
Hamada, S, Gill, K, Slade, H D
The type-specific cell wall polysaccharide antigen was extracted, purified, and characterized from type f Streptococcus mutans strain OMZ175 and MT557. The antigen was extracted from lyophilized...
Hamada, S, Gill, K, Slade, H D
The lectin concanavalin A (Con A) agglutinated the cells of 13 of 15 strains of the seven serotypes of Streptococcus mutans in an 18-h incubation period. Strains of types a, d, f, and g agglutinated...
Streptococcus mutans strain B13 (serotype D) almost exclusively produced free glucosyltransferase (GTase) in the culture supernatant when grown in sucrose-free TTY broth medium, which was composed of...
The possibility that thyroxine (T4) itself exerts the hormonal effect in vivo on the rat liver nuclear receptor was studied with the aid of iopanoic acid (IOP), an inhibitor of the conversion of T4...
Hamada, S, Nakamura, H, Nanno, M, Imura, H
The effect of tri-iodothyronine injection on the nuclear tri-iodothyronine receptor (putative thyroid-hormone receptor) was examined in rat liver. Nuclear receptors were extracted from isolated...
Hamada, S, Nozaki, K, Ito, H, Yoshimoto, Y, Yoshida, H, Hiraga, S, ...
The nature and enzymic properties of starch-branching enzyme (SBE) are two of the dominant factors influencing the fine structure of starch. To understand the role of this enzyme's activity in the...
Glucosyltransferase from Streptococcus sobrinus Catalyzes Glucosylation of Catechin
Nakahara, K., Kontani, M., Ono, H., Kodama, T., Tanaka, T., Ooshima, T., ...
We previously showed that the polymeric forms of polyphenols present in oolong tea extract exhibited strong inhibitory activities against glucosyltransferases (GTases) of mutans streptococci, while...