Scientific Commons: S. Hein

The nonlinear nonlocal transition analysis code NOLOT/PSE is described in detail and its potential is exemplified. The effects of nose bluntness on first- and second-mode boundarylayer instability...

Acoustic Resonances in a 2D High Lift Configuration and 3D Open Cavity (2005)

Hein, S., Koch, W., Schöberl, J.

Acoustic resonances are computed numerically for a generic two-dimensional three-element high lift configuration and a three-dimensional open cavity. Both are major sources of tonal airframe noise....

Akustische Resonanzen in einem Hochauftriebssystem (2005)

Hein, S., Koch, W., Schöberl, J.

Transforming growth factor-beta1 downregulates beating frequency and remodeling of cultured rat adult cardiomyocytes (2005)

Kubin, T., Tomars, M., Fach, C., Hein, S., Bramlage, P., Shim, G. J., ...

We have observed increased levels of transforming growth factor-beta1 (TGF-beta1) in human hibernating myocardium (HM). Impaired ventricular function in HM is known to be restored to normal following...

Transforming growth factor-beta1 downregulates beating frequency and remodeling of cultured rat adult cardiomyocytes (2005)

Kubin, T., Tomars, M., Fach, C., Hein, S., Bramlage, P., Shim, G. J., ...

We have observed increased levels of transforming growth factor-beta1 (TGF-beta1) in human hibernating myocardium (HM). Impaired ventricular function in HM is known to be restored to normal following...

Nonlinear Nonlocal Instability Analyses of Transitional Separation Bubbles (2004)

Hein, S.

The linear and nonlinear instability properties of steady laminar two-dimensional incompressible boundary-layer flows with thin separation bubbles are analyzed by means of nonlocal instability theory...

On instability characteristics of isolated vortices and models of trailing-vortex systems (2004)

Hein, S., Theofilis, Vassilios

This paper demonstrates the applicability of a two-dimensional eigenvalue problem approach to the study of linear instability of analytically constructed and numerically calculated models of...

On resonances in open systems (2004)

Hein, S., Hohage, T., Koch, W.

Remodeling from compensated hypertrophy to heart failure - Structural-functional correlations in the human heart (2004)

Hein, S., Schaper, J.

Matrix metalloproteinases and inhibitors of metalloproteinases in the progression from hypertrophy to heart failure (2004)

Polyakova, V., Hein, S, Kostin, S., Schaper, J.

Matrix metalloproteinases and their tissue inhibitors in pressure-overloaded human myocardium during heart failure progression (2004)

Polyakova, V., Hein, S., Kostin, S., Ziegelhoeffer, T., Schaper, J.

OBJECTIVES: We studied the role of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in fibrosis formation in the transition from hypertrophy to heart failure (HF) as well as the...

Secondary Instability Theory Applied to the Fokker 100 Flight Experiment (2003)

Hein, S., Koch, W.

Absolute/convective instability investigation of primary and secondary crossflow vortices (2003)

Bertolotti, F.P., Hein, S., Stolte, A., Koch, W.

Nonlinear nonlocal transition analysis - code development and results (2003)

Hein, S.

Numerical computation of acoustic resonamces in open systems (2003)

Hein, S., Hohage, T., Koch, W.

Progression from compensated hypertrophy to failure in the pressure-overloaded human heart: structural deterioration and compensatory mechanisms (2003)

Hein, S., Arnon, E., Kostin, S., Schonburg, M., Elsasser, A., Polyakova, V., ...

BACKGROUND: The progression of compensated hypertrophy to heart failure (HF) is still debated. We investigated patients with isolated valvular aortic stenosis and differing degrees of left...

Myocytes die by multiple mechanisms in failing human hearts (2003)

Kostin, S., Pool, L., Elsasser, A., Hein, S., Drexler, H. C., Arnon, E., ...

We tested the hypothesis that myocyte loss in failing human hearts occurs by different mechanisms: apoptosis, oncosis, and autophagic cell death. Explanted hearts from 19 patients with idiopathic...

Gap junction remodeling and altered connexin43 expression in the failing human heart (2003)

Kostin, S., Rieger, M., Dammer, S., Hein, S., Richter, M., Klovekorn, W. P., ...

Gap junctions (GJ) are important determinants of cardiac conduction and the evidence has recently emerged that altered distribution of these junctions and changes in the expression of their...

Porcine aortic endothelial cells show little effects on smooth muscle cells but are potent stimulators of cardiomyocyte growth (2003)

Kubin, T., Vogel, S., Wetzel, J., Hein, S., Pipp, F., Herold, J., ...

Smooth muscle cells (SMC) and endothelial cells (EC) play a pivotal role in arteriogenesis and atherosclerosis. We evaluated the role of EC on the growth of SMC and neonatal cardiomyocytes (NEO) by...

Letter to the editor: Giant molecule titin and myocardial stiffness (2003)

Hein, S., Gaasch, W.H., Schaper, J.

On instability characteristics of isolated vortices and models of trailing-vortex systems. (2002)

Hein, S., Theofilis, V.

Nonlinear Nonlocal Transition Analysis - Code Development and Results -. (2002)

Hein, S.

Giant molecule titin and myocardial stiffness (2002)

Hein, S., Gaasch, W.H., Schaper, J.

Weakness of a giant: mutations of the sarcomeric protein titin (2002)

Hein, S., Schaper, J.

Functional disturbances due to structural remodelling in the failing human heart (2002)

Hein, S., Elsässer, A., Kostin, S., Zimmermann, R., Schaper, J.

Structural correlate of atrial fibrillation in human patients (2002)

Kostin, S., Klein, G., Szalay, Z., Hein, S., Bauer, E.P., Schaper, J.

Structural remodelling in heart failure (2002)

Schaper, J., Kostin, S., Hein, S., Elsässer, A., Arnon, E., Zimmermann, R.

Instability Analysis of Three-Dimensional Vortical Flows. (2001)

Hein, S., Theofilis, V.

Instability Analysis of Three-Dimensional Vortical Flows. (2001)

Hein, S., Theofilis, V.

Receptivity processes and transition scenarios for swept-wing flows with HLF technology. (2001)

Janke, E., Bertolotti, F.P., Hein, S., Koch, W., Stolte, A., Theofilis, V., ...

Nonlinear equilibrium solutions in a three-dimensional boundary layer and their secondary instability (2000)

Koch, W., Bertolotti, F.P., Stolte, A., Hein, S.

Linear and nonlinear instability analysis for two-dimensional laminar separation bubbles (2000)

Hein, S.

Nonlinear Nonlocal Instability Analyses for DLR Test Case within GARTEUR AG27 -Transition on Airfoils and Infinite Swept Wings with Regard to Nonlocal Instability Investigation- (2000)

Hein, S., Dallmann, U.C.

This report is part of the final report of GARTEUR Action Group (AG) 27 'Transition on airfoils and infinite swept wings with regard to nonlocal instability investigation'. The partners in this...

Erste Untersuchungen zur Anwendbarkeit des DLR-TAU-Codes zur Grundströmungsberechnung für nachfolgende Instabilitätsanalysen mit NOLOT/PSE (2000)

Hein, S., Rosenboom, I., Günther, G., Hannemann, V.

On the origins of unsteadiness and three-dimensionality in a laminar separation bubble (2000)

Theofilis, V., Hein, S., Dallmann, U.Ch.

Nonlinear Transition Prediction (2000)

Hein, S., Hanifi, A., Casalis, G.

Laminar-turbulent transition. (2000)

Hein, S.

Identification and Analysis of Nonlinear Transition Scenarios using NOLOT/PSE (1999)

Hein, S., Stolte, A., Dallmann, U.Ch.

Laminar-turbulent transition of quasi-three-dimensional boundary-layer flows is investigated by nonlinear nonlocal instability theory based on parabolized stability equations (PSE). A strong TS-CF...

Entropy-layer instabilities over a blunted flat plate in supersonic flow (1999)

Hein, S., Dietz, G.

Non-linear phenomena modeling (1999)

Hein, S.

Linear and nonlinear nonlocal instability analysis for two-dimensional laminar separation bubbles (1999)

Hein, S.

Entropy-Layer Instabilities in Plane Supersonic Flow (1999)

Dietz, G., Mählmann, S., Hein, S.

Entropy-layer instabilities in the supersonic flow over a blunt flat plate are investigated. Two types of entropy-layer instabilities are identified with the linear, local, parallel stability theory....

Transition on airfoils and infinite swept wings with regard to nonlocal instability investigation. (1999)

Arnal, D., Atkin, C.J., Casalis, G., Dallmann, U.Ch., Hanifi, A., Hein, S., ...

Influence of nose bluntness on boundary-layer instabilities in hypersonic cone flows (1999)

Rosenboom, I., Hein, S., Dallmann, U.C.

Numerische Untersuchungen des Einflusses der Nasenstumpfheit auf Grenzschichtinstabilitäten bei axialsymmetrischer Kegelumströmung im Hyperschall (1998)

Rosenboom, I., Hein, S., Dallmann, U. Ch.

A compressible flat plate test case for nonlinear nonlocal instability investigations in EUROTRANS (1998)

Hein, S., Dallmann, U. Ch.

Experimental and Theoretical Investigations on Transition in Hypersonic Flows at DLR Göttingen (1998)

Hein, S., Wendt, V., Dallmann, U.Ch.

Laminar-turbulent transition of hypersonic boundary-layer flows on sharp ans blunt cones has been studied both in theory and in experiment. Effects of angle of attack are discussed and a transition...

Industrielle Randbedingungen für den aerodynamischen Entwurf von Grenzschichtabsaugesystemen (1998)

Hein, S., Bieler, H., Alewelt, R.

Bei modernen Verkehrsflugzeugen beträgt der Anteil des reibungsbedingten Widerstandes am Gesamtwiderstand mehr als 50%. Dieser Anteil läßt sich durch Technologien der Strömungskontrolle...

Unsteadiness and three-dimensionality of steady two-dimensional laminar separation bubbles as result of linear instability mechanisms (1998)

Hein, S., Theofilis, V., Dallmann, U.

Hadamard Flow around Gas Bubble Observed (1998)

Hein, S., Klein, H., Wittmann, K.

Three-dimensional Centrifugal Instability (1997)

Bippes, H., Hein, S.

At the DLR a research program has been started to study three-dimensional centrifugal instability as appearing in flows over turbine blades. Since up to date very little is known, at the beginning,...

Project FESTIP WP 5000: Critical Point Analysis, WP 5200: Transition,WP 5210 and WP 5220: Synthesis of the Results. Contribution of DLR and FFA (1997)

Hein, S., Herberg, T., Kufner, E., Wendt, V., Dallmann, U., Hanifi, A.(1), ...

Numerische Untersuchungen des Einflusses der Nasenstumpfheit auf Grenzschichtinstabilitaeten bei axialsymmetrischer Kegelumstroemung im Hyperschall. (1997)

Rosenboom, I., Hein, S., Dallmann, U. Ch.

Instabilitaets- und Transitionsuntersuchungen mit NOLOT/PSE im Rahmen von EUROTRANS und GARTEUR. (1997)

Hein, S., Nies, J., Dallmann, U. Ch.

Status of DLR's "Non-Empirical Transition Prediction" Project (1996)

Hein, S., Bertolotti, F.P., Gordner, A., Stolte, A., Koch, W., Bippes, H., ...

Numerical Investigation of the Boundary Layer Instabilities Over a Blunt Flat Plate at Angle of Attack in Supersonic Flow (1996)

Meijering, A.(1), Dietz, G.(2), Hein, S., Dallmann, U.

Nonlocal and Local Instability Analysis of Hypersonic Flows (1996)

Simen, M.(1), Hein, S., Bertolotti, F., Wendt, V., Hanifi, A.(2), Henningson, D.(2)

Nichtlokale Instabilitaetsanalyse kompressibler Seitenleitwerksumstroemungen mit Absaugung (1996)

Gordner, A., Simen, M., Hein, S., Stolte, A., Dallmann, U.

Linear Nonlocal Instability Analysis - the Linear NOLOT Code - (1995)

Hein, S., Bertolotti, F.P., Simen, M., Hanifi, A. (1), Henningson, D. (2)

Nonlocal Instability Analysis of Transonic Flow Past the ATTAS Laminar Glove (1995)

Stolte, A., Bertolotti, F.P., Hein, S., Simen, M.

Nonlocal Instability Analysis of the ATTAS-332 Laminar Glove Flow (1995)

Simen, M., Stolte, A., Bertolotti, F.P., Hein, S.

Nichtlokale und nichtlineare Instabilitaetsuntersuchungen an kompressiblen Stroemungen (1995)

Stolte, A., Bertolotti, F.P., Hein, S., Simen, M., Dallmann, U.

Lokale und nichtlokale Instabilitaetsanalyse dreidimensionaler Grenzschichtstroemungen (1994)

Hein, S. (Vortr.), Huppertz, T., Dallmann, U.

Nonlocal and Local Instability Analysis of Hypersonic Flows (1994)

Simen, M.(Vortr.), Hein, S., Bertolotti, F., Wendt, V., Hanifi, A.(1), Henningson, D.(1)

Nonlocal and Local Instability Analysis of Hypersonic Flows (1994)

Simen, M., Hein, S., Hanifi, A.(1)

Nonlocal and Nonlinear Instability Theory (1994)

Simen, M., Bertolotti, F.P., Hein, S., Henningson, D.(1), Hanifi, A.(1), Dallmann, U. (Vortr.)

Lokale und nichtlokale Instabilitaetsanalyse dreidimensionaler Grenzschichtstroemungen (1994)

Hein, S. (Vortr.), Huppertz, T., Dallmann, U.

Instabilitätsuntersuchungen der Grundströmung an stumpfen Kegeln bei hypersonischen Machzahlen (1993)

Kufner, E., Hein, S., Dallmann, U.

Vortices in infinite free Bose systems (1980)

Hein, S., Roepstorff, G.

Biochemical and molecular characterization of the Alcaligenes eutrophus pyruvate dehydrogenase complex and identification of a new type of dihydrolipoamide dehydrogenase.

Hein, S, Steinbüchel, A

Sequence analysis of a 6.3-kbp genomic EcoRI-fragment of Alcaligenes eutrophus, which was recently identified by using a dihydrolipoamide dehydrogenase-specific DNA probe (A. Pries, S. Hein, and A....

Identification and molecular characterization of the Alcaligenes eutrophus H16 aco operon genes involved in acetoin catabolism.

Priefert, H, Hein, S, Krüger, N, Zeh, K, Schmidt, B, Steinbüchel, A

Acetoin:dichlorophenolindophenol oxidoreductase (Ao:DCPIP OR) and the fast-migrating protein (FMP) were purified to homogeneity from crude extracts of acetoin-grown cells of Alcaligenes eutrophus....

Biochemical and molecular characterization of the Alcaligenes eutrophus pyruvate dehydrogenase complex and identification of a new type of dihydrolipoamide dehydrogenase.

Hein, S, Steinbüchel, A

Sequence analysis of a 6.3-kbp genomic EcoRI-fragment of Alcaligenes eutrophus, which was recently identified by using a dihydrolipoamide dehydrogenase-specific DNA probe (A. Pries, S. Hein, and A....

Identification and molecular characterization of the Alcaligenes eutrophus H16 aco operon genes involved in acetoin catabolism.

Priefert, H, Hein, S, Krüger, N, Zeh, K, Schmidt, B, Steinbüchel, A

Acetoin:dichlorophenolindophenol oxidoreductase (Ao:DCPIP OR) and the fast-migrating protein (FMP) were purified to homogeneity from crude extracts of acetoin-grown cells of Alcaligenes eutrophus....

S. Hein

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