The Effects of Magnetic Fields and Inhomogeneities on Accretion Disk Spectra and Polarization (2009)
Davis, S. W., Blaes, O. M., Hirose, S., Krolik, J. H.
We present the results of one and three-dimensional radiative transfer calculations of polarized spectra emerging from snapshots of radiation magnetohydrodynamical simulations of the local vertical...
Sasakura, H., Adachi, S., Muto, S., Hirose, S., Song, H. Z., Takatsu, M.
We have demonstrated experimentally the manipulation of exciton and nuclear spins in a single self-assembled In$_{0.75}$Al$_{0.25}$As/Al$_{0.3}$Ga$_{0.7}$As quantum dot. The oscillation of exciton...
Magnetic pressure support and accretion disk spectra (2006)
Blaes, O. M., Davis, S. W., Hirose, S., Krolik, J. H., Stone, J. M.
Stellar atmosphere models of ionized accretion disks have generally neglected the contribution of magnetic fields to the vertical hydrostatic support, although magnetic fields are widely believed to...
Single-photon generation from InAlAs single quantum dot (2005)
Kimura, S, Kumano, H, Endo, M, Suemune, I, Yokoi, T, Sasakura, H, ...
Regulated single-photon generation from an InAlAs quantum dot was demonstrated at a wavelength in which Si-avalanche photodiode single-photon detector has high quantum efficiency. Measured excitation...
Single-photon generation from InAlAs single quantum dot (2005)
Kimura, S, Kumano, H, Endo, M, Suemune, I, Yokoi, T, Sasakura, H, ...
Regulated single-photon generation from an InAlAs quantum dot was demonstrated at a wavelength in which Si-avalanche photodiode single-photon detector has high quantum efficiency. Measured excitation...
Single-photon generation from InAlAs single quantum dot (2005)
Kimura, S, Kumano, H, Endo, M, Suemune, I, Yokoi, T, Sasakura, H, ...
Regulated single-photon generation from an InAlAs quantum dot was demonstrated at a wavelength in which Si-avalanche photodiode single-photon detector has high quantum efficiency. Measured excitation...
The search for optical emission on and before the GRB trigger with the WIDGET telescope (2005)
Tamagawa, T., Usui, F., Urata, Y., Abe, K., Onda, K., Tashiro, M., ...
WIDGET is a robotic telescope for monitoring the HETE-2 field-of-view to detect Gamma-ray Burst optical flashes or possible optical precursors. The system has 62degx62deg wide field-of-view which...
Yokoi, T., Adachi, S., Sasakura, H., Muto, S., Song, H. Z., Usuki, T., ...
We report the optical spectroscopic results of a single self-assembled InAlAs/Al GaAs quantum dot. The polarization-dependent shift of the Zeeman splitting in a single InAlAs QD has been observed....
A selection of results from the general relativistic MHD accretion simulations described in the previous talk are presented. We find that the magnetic field strength increases sharply with decreasing...
Kigure, H., Uchida, Y., Nakamura, M., Hirose, S., Cameron, R.
Distributions of Faraday rotation measure (FRM) and the projected magnetic field derived by a 3-dimensional simulation of MHD jets are investigated based on our "sweeping magnetic twist model". FRM...
Uchida, Y., Kigure, H., Hirose, S., Nakamura, M., Cameron, R.
Using the numerical data of MHD simulation for AGN jets based on our ``sweeping magnetic twist model'', we calculated the Faraday rotation measure (FRM) and the Stokes parameters to compare with...
Hirose, S., Litvinenko, Y., Tanuma, S., Shibata, K., Takahashi, M., Tanigawa, T., ...
The Kelvin--Helmholtz (KH) and tearing instabilities are likely to be important for the process of fast magnetic reconnection that is believed to explain the observed explosive energy release in...
Triaxial deformation in 10Be (2002)
Itagaki, N., Hirose, S., Otsuka, T., Okabe, S., Ikeda, K.
The triaxial deformation in 10Be is investigated using a microscopic α+α+n+n model. The states of two valence neutrons are classified based on the molecular-orbit (MO) model, and the π orbit is...
Triaxial deformation in 10Be (2002)
Itagaki, N., Hirose, S., Otsuka, T., Okabe, S., Ikeda, K.
The triaxial deformation in 10Be is investigated using a microscopic α+α+n+n model. The states of two valence neutrons are classified based on the molecular-orbit (MO) model, and the π orbit is...
Triaxial deformation in 10Be (2001)
Itagaki, N., Hirose, S., Otsuka, T., Okabe, S., Ikeda, K.
The triaxial deformation in $^{10}$Be is investigated using a microscopic $\alpha+\alpha+n+n$ model. The states of two valence neutrons are classified based on the molecular-orbit (MO) model, and the...
Antiphospholipid antibody-associated haemophagocytic syndrome (2000)
Ikeda, K., Nawata, M., Ando, S., Koike, M., Sekigawa, I., Iida, N., ...
X-trap influence on luminescence and electric properties of C-60 single crystal (1998)
Kolmakov, A., Stankevitch, V., Svechnikov, N., Dudin, P., Artemiev, N., Berger, H., ...
This paper is devoted to investigation of luminescence and some electric properties of C-60 single crystal and their connection with X-traps model. Luminescence properties for C-60 single crystal,...
Y. Shirai, S. Hirose, Louis Whitcomb, Dana Yoerger, Hanumant Singh, David Mindell
This paper reports recent advances in the precision control of underwater robotic vehicles for survey and manipulation missions. A new underwater vehicle navigation and control system employing a new...
Miyazaki, S, Shimura, J, Hirose, S, Sanokawa, R, Tsurui, H, Wakiya, M, ...
Temperature dependence of luminescence intensity and decay times in C-60 single crystal (1996)
Kolmakov, A., Stankevitch, V., Svechnikov, N., Dudin, P., Artemev, N., Berger, H., ...
Luminescence properties for C-60 single crystal, the temperature dependence of the luminescence spectra and decay kinetics were measured for a wide range of excitation energies. At low temperatures...
Complexity of Boolean functions satisfying the propagation criterion (1995)
S. Hirose, K. Ikeda, Hirose Shouichi, Ikeda Katsuo
Complexity of Boolean functions satisfying the propagation criterion(PC), an extended notion of the perfect nonlinearity, is discussed on several computation models. The following topics are...
Imai, S., Tokuyama, M., Hirose, S., Burger, G.J., Lammerink, T.S.J., Fluitman, J.H.J.
A new type of Acoustic Emission sensor using a thin film piezoelectric material (sputtered ZnO) was developed for measuring head-disk interaction in a rigid magnetic disk system. The sensor is...
Piezoelectric impact force sensor array for tribological research on rigid disk storage media (1995)
Burger, G.J., Lammerink, T.S.J., Fluitman, J.H.J., Imai, S., Tokuyama, M., Hirose, S.
This paper presents a method to measure impact forces on a surface by means of a piezoelectric thin film sensor array. The output signals of the sensor array provide information about the position,...
Control of imaginal cell development by the escargot gene of Drosophila. (1993)
Hayashi, S., Hirose, S., Metcalfe, T., Shirras, A. D.
Mutations in the escargot (esg) locus, which codes for a zinc-finger-containing protein with similarity to the product of the snail gene, cause a variety of defects in adult structures such as loss...
Luminescence of high-temperature single-crystal superconductors cleaved in ultrahigh vacuum. (1993)
Stankevitch, V.G., Svechnikov, N.Yu., Kaznacheev, K.V., Kamada, M., Tanaka, S., Hirose, S., ...
Physical Review B, 47(1993) S.1024-28
Hirose, S, Ravi, L, Prince, G M, Rosenfeld, M G, Silber, R, Andresen, S W, ...
To identify mannosyl (Man)-containing intermediates of the human glycoinositol phospholipid (GPI) anchor pathway and examine their expression in paroxysmal nocturnal hemoglobinuria (PNH), mannolipid...
Hirose, S, Ravi, L, Hazra, S V, Medof, M E
Decay-accelerating factor (DAF) is anchored in cell membranes by a glycosyl-plasmanylinositol (GPI) moiety that is transferred to it en bloc in the rough endoplasmic reticulum. To analyze the...
Hasegawa, K., Abe, M., Okada, T., Hirose, S., Sato, H., Shiral, T., ...
Unlike splenic B cells from normal BALB/c mice, those from autoimmune-prone NZB × NZW (B/W) F1 young mice were hyperresponsive to interleukln 2 (IL2) and proliferated even in the absence of...
Tokunaga, K., Hirose, S., Suzuki, Y.
The DNA sequences necessary for faithful and efficient initiation of transcription of Bombyx mori fibronin gene have been studied in vivo COS using monkey COS celia and a SV40 origin vector....
Nakanishi, K, Hirose, S, Yoshimoto, T, Ishizashi, H, Hiroishi, K, Tanaka, T, ...
Substantial proportions of resting B cells constitutively express low levels of IL-2 receptor (IL-2R) alpha and/or beta chains. The expression of these chains is differentially regulated by anti-IgM...
Mizutani, M, Ohta, T, Watanabe, H, Handa, H, Hirose, S
Transcription of the fibroin gene can be reconstituted with partially purified components from HeLa cells. Transcription factors IIB, IID, and IIE and RNA polymerase II are required for accurate...
Hirose, S, Ravi, L, Hazra, S V, Medof, M E
Decay-accelerating factor (DAF) is anchored in cell membranes by a glycosyl-plasmanylinositol (GPI) moiety that is transferred to it en bloc in the rough endoplasmic reticulum. To analyze the...
Purification of a DNA supercoiling factor from the posterior silk gland of Bombyx mori.
A protein factor with an estimated molecular mass of 50 kDa has been purified to homogeneity from the silk gland of Bombyx mori. In the presence of a molar excess of this factor and eukaryotic DNA...
Kaneko, H, Neoh, L P, Takeda, N, Akimoto, H, Hishikawa, T, Hashimoto, H, ...
We report here that human immunodeficiency virus type 2 (HIV-2) envelope glycoprotein (gp105), but not HIV-1 gp120, can bind to CD8 molecules as well as to CD4 molecules on human T cells. This...
Igarashi, K, Kashiwagi, K, Hamasaki, H, Miura, A, Kakegawa, T, Hirose, S, ...
The amounts of normal and compensatory polyamines of polyamine-requiring Escherichia coli mutants grown in the absence of polyamines were determined. Although aminopropylcadaverine, a compensatory...
Regulation of the EDG84A gene by FTZ-F1 during metamorphosis in Drosophila melanogaster.
Murata, T, Kageyama, Y, Hirose, S, Ueda, H
The transcription factor FTZ-F1 is a member of the nuclear hormone receptor superfamily and is transiently expressed during the mid- and late prepupal periods in Drosophila melanogaster. A putative...
Fujii, N, Kotake, S, Hirose, S, Ohno, S, Yasuda, I, Sagawa, A, ...
Interferon induces oligo-2',5'-adenylate synthetase in cells. In various diseases, interferon was detectable in the circulation or was produced spontaneously from peripheral blood mononuclear...
In a posterior silk gland extract, covalently closed circular (ccc) DNA is in a superhelical state that supports more transcription of fibroin gene than does linear DNA. A HeLa cell extract showed...
Tokunaga, K, Hirose, S, Suzuki, Y
The DNA sequences necessary for faithful and efficient initiation of transcription of Bombyx mori fibroin gene have been studied in vivo using monkey COS cells and a SV40 origin vector....
Promoter sequence of fibroin gene assigned by in vitro transcription system.
Tsujimoto, Y, Hirose, S, Tsuda, M, Suzuki, Y
We have shown that the silk fibroin gene from Bombyx mori is faithfully transcribed in an in vitro transcription system of the HeLa cell extract prepared by the method of Manley et al. [Manley, J....
Mizutani, M, Ura, K, Hirose, S
In vitro transcription was reconstituted with HeLa cell transcription factors and RNA polymerase II, which were essentially free from DNA topoisomerase activities. DNA templates with defined negative...
BmFTZ-F1 is a Bombyx mori homologue of FTZ-F1, a positive regulator of the fushi tarazu gene of Drosophila melanogaster. In order to determine the sequence recognized with this factor, we made three...
The Hox-2.1 gene is one of homeobox-containing genes located in the Hox-2 cluster on mouse chromosome 11. In this study, we have examined transcription of the Hox-2.1 gene during differentiation of...
Identification and purification of a Bombyx mori homologue of FTZ-F1.
Extracts from embryos and from posterior and middle silk glands of the silkworm, Bombyx mori contain a sequence specific DNA binding factor termed BmFTZ-F1. The factor binds to the recognition site...
Hirose, S, Takeuchi, K, Hori, H, Hirose, T, Inayama, S, Suzuki, Y
An efficient method for oligonucleotide-directed mutagenesis was developed to construct a set of site-specific mutations by using a mixture of oligodeoxyribonucleotides. With this method, as high as...
Hirose, S, Takeuchi, K, Suzuki, Y
A highly efficient method for segment-directed mutagenesis has been developed. The method relies on the deamination by sodium nitrite of the bases in the separated strands of a small DNA restriction...
Mediators of activation of fushi tarazu gene transcription by BmFTZ-F1.
Transcriptional activation by many eukaryotic sequence-specific regulators appears to be mediated through transcription factors which do not directly bind to DNA. BmFTZ-F1 is a silkworm counterpart...
Ueda, H, Sun, G C, Murata, T, Hirose, S
Fruit fly FTZ-F1, silkworm BmFTZ-F1, and mouse embryonal long terminal repeat-binding protein are members of the nuclear hormone receptor superfamily, which recognizes the same sequence,...
Tsuda, M, Hirose, S, Suzuki, Y
The addition of exogenous histones has an inhibitory effect on fibroin gene transcription in posterior silk gland extracts. The histones probably disturb a process in complex formation, because when...
Tsukiyama, T, Ueda, H, Hirose, S, Niwa, O
The embryonal long terminal repeat-binding protein, ELP, is present in undifferentiated mouse embryonal carcinoma cells. It binds to and suppresses transcription of the Moloney leukemia virus long...
Sato, C, Nishizawa, K, Nakayama, T, Nose, K, Takasaki, Y, Hirose, S, ...
Cytoskeleton-associated 350-kDa and 80-kDa polypeptides, which were immunoprecipitated with polyclonal antibody against microtubule-associated protein 1 (MAP-1), were rapidly phosphorylated on...
Tissue-specific transcription enhancement of the fibroin gene characterized by cell-free systems.
Suzuki, Y, Tsuda, M, Takiya, S, Hirose, S, Suzuki, E, Kameda, M, ...
Six cell-free extracts have been used to characterize the nature of DNA signals and trans-acting factors responsible for the transcription enhancement of the Bombyx mori fibroin gene. The upstream...
Cloning and sequence analysis of cDNA for human renin precursor.
Imai, T, Miyazaki, H, Hirose, S, Hori, H, Hayashi, T, Kageyama, R, ...
The primary structure of human renin precursor has been deduced from its cDNA sequence. A library of cDNA clones was constructed from human kidney poly(A)+ RNA by applying the vector/primer method of...
Structure of the human renin gene.
Miyazaki, H, Fukamizu, A, Hirose, S, Hayashi, T, Hori, H, Ohkubo, H, ...
The human renin gene was isolated from a Charon 4A human genomic library and characterized. The gene spans about 11.7 kilobases and consists of 10 exons and 9 introns that map at points that could be...
Hirose, S, Ravi, L, Prince, G M, Rosenfeld, M G, Silber, R, Andresen, S W, ...
To identify mannosyl (Man)-containing intermediates of the human glycoinositol phospholipid (GPI) anchor pathway and examine their expression in paroxysmal nocturnal hemoglobinuria (PNH), mannolipid...
Core promoter of the mouse myelin basic protein gene governs brain-specific transcription in vitro.
Tamura, T, Sumita, K, Hirose, S, Mikoshiba, K
The core promoter of the mouse myelin basic protein (MBP) gene from -36 to +12 was preferentially transcribed in brain nuclear extracts. Both the TATA at -34 and downstream elements to +12 were...
Structure of the bovine ETB endothelin receptor gene.
Mizuno, T, Saito, Y, Itakura, M, Ito, F, Ito, T, Moriyama, E N, ...
The structure of the gene encoding the bovine type B endothelin receptor (ETB) has been established and compared with those of other heptahelical receptors. The gene is present as a single copy in...
Purification and properties of active atrial-natriuretic-peptide receptor (type C) from bovine lung.
Uchida, K, Mizuno, T, Shimonaka, M, Sugiura, N, Nara, K, Ling, N, ...
Atrial-natriuretic-peptide (ANP) receptor, previously identified as a 140 kDa protein with a disulphide-linked homodimeric structure, was purified from bovine lung by (NH4)2SO4 fractionation and...
Biosynthesis, assembly and secretion of fibrinogen in cultured rat hepatocytes.
The biosynthesis, assembly and secretion of fibrinogen were investigated in cultured rat hepatocytes which were incubated with [35S]methionine. When initial rates of the synthesis of three fibrinogen...
Structural analysis of natriuretic peptide receptor-C by truncation and site-directed mutagenesis.
Itakura, M, Suzuki, H, Hirose, S
Natriuretic peptide receptor-C (NPR-C) has a unique structure consisting of pre-existing covalent homodimers, but it is not known whether each subunit has ligand-binding activity or whether the...
Nagase, M, Hirose, S, Fujita, T
We report the identification of a unique repetitive sequence in the rat endothelial receptor for oxidized low-density lipoprotein (LOX-1) and unexpected blood-pressure-associated regulation of its...
Schalkwijk, J, Wiedow, O, Hirose, S
Recently, several new genes have been discovered in various species which are homologous to the well-characterized human epithelial proteinase inhibitor elafin/SKALP (skin-derived...
Nakamura, N, Suzuki, Y, Sakuta, H, Ookata, K, Kawahara, K, Hirose, S
A novel inwardly rectifying K+ channel, Kir7.1, with unique pore properties, was cloned recently. Working in the field of osmoregulation, we have also identified the same human and rat channel and...
Mistry, A C, Honda, S, Hirose, S
Using a Japanese-eel (Anguilla japonica) gill cDNA subtraction library, two novel beta-d-galactose-binding lectins were identified that belong to group VII of the animal C-type lectin family. The eel...
Nakanishi, K, Hirose, S, Yoshimoto, T, Ishizashi, H, Hiroishi, K, Tanaka, T, ...
Substantial proportions of resting B cells constitutively express low levels of IL-2 receptor (IL-2R) alpha and/or beta chains. The expression of these chains is differentially regulated by anti-IgM...
Mizutani, M, Ohta, T, Watanabe, H, Handa, H, Hirose, S
Transcription of the fibroin gene can be reconstituted with partially purified components from HeLa cells. Transcription factors IIB, IID, and IIE and RNA polymerase II are required for accurate...
Hirose, S, Ravi, L, Hazra, S V, Medof, M E
Decay-accelerating factor (DAF) is anchored in cell membranes by a glycosyl-plasmanylinositol (GPI) moiety that is transferred to it en bloc in the rough endoplasmic reticulum. To analyze the...
Purification of a DNA supercoiling factor from the posterior silk gland of Bombyx mori.
A protein factor with an estimated molecular mass of 50 kDa has been purified to homogeneity from the silk gland of Bombyx mori. In the presence of a molar excess of this factor and eukaryotic DNA...
Kaneko, H, Neoh, L P, Takeda, N, Akimoto, H, Hishikawa, T, Hashimoto, H, ...
We report here that human immunodeficiency virus type 2 (HIV-2) envelope glycoprotein (gp105), but not HIV-1 gp120, can bind to CD8 molecules as well as to CD4 molecules on human T cells. This...
Igarashi, K, Kashiwagi, K, Hamasaki, H, Miura, A, Kakegawa, T, Hirose, S, ...
The amounts of normal and compensatory polyamines of polyamine-requiring Escherichia coli mutants grown in the absence of polyamines were determined. Although aminopropylcadaverine, a compensatory...
Regulation of the EDG84A gene by FTZ-F1 during metamorphosis in Drosophila melanogaster.
Murata, T, Kageyama, Y, Hirose, S, Ueda, H
The transcription factor FTZ-F1 is a member of the nuclear hormone receptor superfamily and is transiently expressed during the mid- and late prepupal periods in Drosophila melanogaster. A putative...
Fujii, N, Kotake, S, Hirose, S, Ohno, S, Yasuda, I, Sagawa, A, ...
Interferon induces oligo-2',5'-adenylate synthetase in cells. In various diseases, interferon was detectable in the circulation or was produced spontaneously from peripheral blood mononuclear...
In a posterior silk gland extract, covalently closed circular (ccc) DNA is in a superhelical state that supports more transcription of fibroin gene than does linear DNA. A HeLa cell extract showed...
Tokunaga, K, Hirose, S, Suzuki, Y
The DNA sequences necessary for faithful and efficient initiation of transcription of Bombyx mori fibroin gene have been studied in vivo using monkey COS cells and a SV40 origin vector....
Promoter sequence of fibroin gene assigned by in vitro transcription system.
Tsujimoto, Y, Hirose, S, Tsuda, M, Suzuki, Y
We have shown that the silk fibroin gene from Bombyx mori is faithfully transcribed in an in vitro transcription system of the HeLa cell extract prepared by the method of Manley et al. [Manley, J....
Mizutani, M, Ura, K, Hirose, S
In vitro transcription was reconstituted with HeLa cell transcription factors and RNA polymerase II, which were essentially free from DNA topoisomerase activities. DNA templates with defined negative...
BmFTZ-F1 is a Bombyx mori homologue of FTZ-F1, a positive regulator of the fushi tarazu gene of Drosophila melanogaster. In order to determine the sequence recognized with this factor, we made three...
The Hox-2.1 gene is one of homeobox-containing genes located in the Hox-2 cluster on mouse chromosome 11. In this study, we have examined transcription of the Hox-2.1 gene during differentiation of...
Identification and purification of a Bombyx mori homologue of FTZ-F1.
Extracts from embryos and from posterior and middle silk glands of the silkworm, Bombyx mori contain a sequence specific DNA binding factor termed BmFTZ-F1. The factor binds to the recognition site...
Hirose, S, Takeuchi, K, Hori, H, Hirose, T, Inayama, S, Suzuki, Y
An efficient method for oligonucleotide-directed mutagenesis was developed to construct a set of site-specific mutations by using a mixture of oligodeoxyribonucleotides. With this method, as high as...
Hirose, S, Takeuchi, K, Suzuki, Y
A highly efficient method for segment-directed mutagenesis has been developed. The method relies on the deamination by sodium nitrite of the bases in the separated strands of a small DNA restriction...
Mediators of activation of fushi tarazu gene transcription by BmFTZ-F1.
Transcriptional activation by many eukaryotic sequence-specific regulators appears to be mediated through transcription factors which do not directly bind to DNA. BmFTZ-F1 is a silkworm counterpart...
Ueda, H, Sun, G C, Murata, T, Hirose, S
Fruit fly FTZ-F1, silkworm BmFTZ-F1, and mouse embryonal long terminal repeat-binding protein are members of the nuclear hormone receptor superfamily, which recognizes the same sequence,...
Tsuda, M, Hirose, S, Suzuki, Y
The addition of exogenous histones has an inhibitory effect on fibroin gene transcription in posterior silk gland extracts. The histones probably disturb a process in complex formation, because when...
Tsukiyama, T, Ueda, H, Hirose, S, Niwa, O
The embryonal long terminal repeat-binding protein, ELP, is present in undifferentiated mouse embryonal carcinoma cells. It binds to and suppresses transcription of the Moloney leukemia virus long...
Sato, C, Nishizawa, K, Nakayama, T, Nose, K, Takasaki, Y, Hirose, S, ...
Cytoskeleton-associated 350-kDa and 80-kDa polypeptides, which were immunoprecipitated with polyclonal antibody against microtubule-associated protein 1 (MAP-1), were rapidly phosphorylated on...
Tissue-specific transcription enhancement of the fibroin gene characterized by cell-free systems.
Suzuki, Y, Tsuda, M, Takiya, S, Hirose, S, Suzuki, E, Kameda, M, ...
Six cell-free extracts have been used to characterize the nature of DNA signals and trans-acting factors responsible for the transcription enhancement of the Bombyx mori fibroin gene. The upstream...
Cloning and sequence analysis of cDNA for human renin precursor.
Imai, T, Miyazaki, H, Hirose, S, Hori, H, Hayashi, T, Kageyama, R, ...
The primary structure of human renin precursor has been deduced from its cDNA sequence. A library of cDNA clones was constructed from human kidney poly(A)+ RNA by applying the vector/primer method of...
Structure of the human renin gene.
Miyazaki, H, Fukamizu, A, Hirose, S, Hayashi, T, Hori, H, Ohkubo, H, ...
The human renin gene was isolated from a Charon 4A human genomic library and characterized. The gene spans about 11.7 kilobases and consists of 10 exons and 9 introns that map at points that could be...
Hirose, S, Ravi, L, Prince, G M, Rosenfeld, M G, Silber, R, Andresen, S W, ...
To identify mannosyl (Man)-containing intermediates of the human glycoinositol phospholipid (GPI) anchor pathway and examine their expression in paroxysmal nocturnal hemoglobinuria (PNH), mannolipid...
Core promoter of the mouse myelin basic protein gene governs brain-specific transcription in vitro.
Tamura, T, Sumita, K, Hirose, S, Mikoshiba, K
The core promoter of the mouse myelin basic protein (MBP) gene from -36 to +12 was preferentially transcribed in brain nuclear extracts. Both the TATA at -34 and downstream elements to +12 were...
Structure of the bovine ETB endothelin receptor gene.
Mizuno, T, Saito, Y, Itakura, M, Ito, F, Ito, T, Moriyama, E N, ...
The structure of the gene encoding the bovine type B endothelin receptor (ETB) has been established and compared with those of other heptahelical receptors. The gene is present as a single copy in...
Purification and properties of active atrial-natriuretic-peptide receptor (type C) from bovine lung.
Uchida, K, Mizuno, T, Shimonaka, M, Sugiura, N, Nara, K, Ling, N, ...
Atrial-natriuretic-peptide (ANP) receptor, previously identified as a 140 kDa protein with a disulphide-linked homodimeric structure, was purified from bovine lung by (NH4)2SO4 fractionation and...
Biosynthesis, assembly and secretion of fibrinogen in cultured rat hepatocytes.
The biosynthesis, assembly and secretion of fibrinogen were investigated in cultured rat hepatocytes which were incubated with [35S]methionine. When initial rates of the synthesis of three fibrinogen...
Structural analysis of natriuretic peptide receptor-C by truncation and site-directed mutagenesis.
Itakura, M, Suzuki, H, Hirose, S
Natriuretic peptide receptor-C (NPR-C) has a unique structure consisting of pre-existing covalent homodimers, but it is not known whether each subunit has ligand-binding activity or whether the...
Nagase, M, Hirose, S, Fujita, T
We report the identification of a unique repetitive sequence in the rat endothelial receptor for oxidized low-density lipoprotein (LOX-1) and unexpected blood-pressure-associated regulation of its...
Schalkwijk, J, Wiedow, O, Hirose, S
Recently, several new genes have been discovered in various species which are homologous to the well-characterized human epithelial proteinase inhibitor elafin/SKALP (skin-derived...
Nakamura, N, Suzuki, Y, Sakuta, H, Ookata, K, Kawahara, K, Hirose, S
A novel inwardly rectifying K+ channel, Kir7.1, with unique pore properties, was cloned recently. Working in the field of osmoregulation, we have also identified the same human and rat channel and...
Mistry, A C, Honda, S, Hirose, S
Using a Japanese-eel (Anguilla japonica) gill cDNA subtraction library, two novel beta-d-galactose-binding lectins were identified that belong to group VII of the animal C-type lectin family. The eel...
Apoptosis with FasL+ cell infiltration in the periphery and thymus of corrected autoimmune mice.
Kobata, T, Takasaki, K, Asahara, H, Hong, N M, Masuko-Hongo, K, Kato, T, ...
Fas (CD95) ligand (L) is a death factor that binds to its receptor, Fas, and induces apoptotic cell death, a crucial process in immunological tolerance. gld (generalized lymphoproliferative disorder)...
Tokushima, M, Koarada, S, Hirose, S, Gotoh, Y, Nishimura, H, Shirai, T, ...
We characterized autoreactive T-cell clones derived from (NZB x NZW)F1 (B/WF1) mice. These autoreactive T-cell clones are shown to be CD4+ by immunofluorescence staining and to belong to Th2 type by...
Tokano, Y, Murashima, A, Takasaki, Y, Hashimoto, H, Okumura, K, Hirose, S
The concentration of soluble interleukin 2 receptor (IL-2R) was determined in the serum of 54 patients with systemic lupus erythematosus (SLE) by an enzyme linked immunosorbent assay (ELISA) using...
Nakajima, H, Hiyama, Y, Tsukada, W, Warabi, H, Uchida, S, Hirose, S
The effects of recombinant interferon gamma (rIFN gamma) on the in vitro growth of adherent synovial fibroblast-like cells from patients with rheumatoid arthritis (RA) and also on the release of...
Immunoadsorbent plasmapheresis for a patient with antiphospholipid syndrome during pregnancy.
Kobayashi, S, Tamura, N, Tsuda, H, Mokuno, C, Hashimoto, H, Hirose, S
The case of a 34 year old woman with systemic lupus erythematosus with a history of three previous recurrent abortions and lupus anticoagulant and anticardiolipin antibodies is reported....
Noguchi, M, Iwamori, M, Hirano, T, Kobayashi, S, Hashimoto, H, Hirose, S, ...
Antibodies to lymphocytes in serum samples from 88 patients with systemic lupus erythematosus (SLE) and 15 normal control subjects were examined by a cell enzyme linked immunosorbent assay (ELISA)...
Soluble interleukin 2 receptors in patients with polymyositis/dermatomyositis.
Tokano, Y, Kanai, Y, Hashimoto, H, Okumura, K, Hirose, S
The concentration of soluble interleukin 2 receptor was determined in serum samples from 19 patients with polymyositis/dermatomyositis by an enzyme linked immunosorbent assay (ELISA). The...
False negative results of anticardiolipin antibody test.
Kobayashi, S, Tanaka, M, Tsuda, H, Hashimoto, H, Hirose, S, Saikawa, T, ...
Subretinal neovascularisation and snow banking in a case of sarcoidosis: case report.
Pellegrini, V., Ohno, S., Hirose, S., Matsuda, H., Hiraga, Y.
A 49-year-old Japanese man presented with chronic granulomatous uveitis in his left eye. Later he developed macular subretinal neovascularisation. The chest x-ray showed bilateral hilar...
Genetic evolution of α fetoprotein producing gastric cancer
Fujii, H, Ichikawa, K, Takagaki, T, Nakanishi, Y, Ikegami, M, Hirose, S, ...
Background: α Fetoprotein (AFP) producing gastric cancer is an unusual form of aggressive adenocarcinoma with a complex histological picture, including enteroblastic and hepatoid differentiation.
An 18-mer peptide derived from the retinal S antigen induces uveitis and pinealitis in primates.
Hirose, S, Singh, V K, Donoso, L A, Shinohara, T, Kotake, S, Tanaka, T, ...
S-antigen, a photoreceptor cell protein, induces a predominantly T-cell mediated autoimmune uveitis in many vertebrate animals, including primates. Because of this activity and the finding of immune...
Regulation of experimental autoimmune uveitis in rats--separation of MHC and non-MHC gene effects.
Hirose, S, Ogasawara, K, Natori, T, Sasamoto, Y, Ohno, S, Matsuda, H, ...
Experimental autoimmune uveitis (EAU) is an organ-specific autoimmune disease and has served as a model of certain ocular inflammatory conditions in man. The present study was aimed at separating the...
Hirose, S, Sekigawa, I, Ozaki, S, Sato, H, Shirai, T
To determine the inheritance patterns of both IgM class and IgG class hypergammaglobulinaemias, the locations of genes and the relations of these genes to other autoimmune traits in NZB X NZW (B/W)...
Genetic studies on the skin lupus band test in New Zealand mice.
Furukawa, F, Maruyama, N, Yoshida, H, Hamashima, Y, Hirose, S, Shirai, T
We found that the lupus band test (LBT) is frequently positive in the tail skin in NZB and NZB X NZW (B/W) F1 hybrid mice. Genetic mode of development of this positivity was investigated in female...
The change in C3b receptors on erythrocytes from patients with systemic lupus erythematosus.
Yoshida, K, Yukiyama, Y, Hirose, S, Miyamoto, T
A deficiency of C3b receptors (CR1) on erythrocytes from patients with systemic lupus erythematosus (SLE) has already been reported and assumed to be one of the causes of the impaired immune complex...
Inhibitory effect of interleukin-16 on interleukin-2 production by CD4+ T cells
Ogasawara, H, Takeda-Hirokawa, N, Sekigawa, I, Hashimoto, H, Kaneko, Y, Hirose, S
Signalling through CD4 by human immunodeficiency virus (HIV)-1 envelope glycoprotein (gpl20) and/or anti-CD4 antibodies can promote T-cell activation and anergy. Interleukin (IL)-16 is a competence...