S. Holmberg

Publication List Details

Period

1982 - 2009

Number

58

Co-Authors

Timing of CMF chemotherapy in combination with tamoxifen in postmenopausal women with breast cancer: role of endocrine responsiveness of the tumor (2005)

Colleoni, M., Li, S., Gelber, R. D., Coates, A. S., Castiglione-Gertsch, M., Price, K. N., ...

Background:: Controversy persists about whether chemotherapy benefits all breast cancer patients. Patients and methods:: In the International Breast Cancer Study Group (IBCSG) trial VII, 1212...

Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells (2001)

Samuelsen, C O, Baraznenok, V, Remacle, J E, ...

With the identification of eight new polypeptides, we here complete the subunit characterization of the Schizosaccharomyces pombe RNA polymerase II holoenzyme. The complex contains homologs to all 10...

Factors modifying the effect of bystander cardiopulmonary resuscitation on survival in out-of-hospital cardiac arrest patients in Sweden (2001)

Holmberg, M, Holmberg, S, Herlitz, J

Aim To describe possible factors modifying the effect of bystander cardiopulmonary resuscitation on survival among patients suffering an out-of-hospital cardiac arrest. Patients A national survey in...

Political parties in decline? (1995)

Schmitt, H., Holmberg, S.

Discusses the theory and concepts of partisanship. Using indicators of the strength of party identification—or party attachment—as its main analytical tool, it traces the development of...

Survival in patients found to have ventricular fibrillation after cardiac arrest witnessed outside hospital (1994)

HERLITZ, J., EKSTRÕM, L., WENNERBLOM, B., AXELSSON, Å., BÅNG, A., HOLMBERG, S.

Since 1980 an Emergency Medical Service (EMS) system with a two-tier ambulance service has been operating in Göteborg. During this 12-year period, all cardiac arrests outside hospital have been...

Follow-up of a 1-year media campaign on delay times and ambulance use in suspected acute myocardial infarction (1992)

HERLITZ, J., BLOHM, M., HARTFORD, M., KARLSON, B. W., LUEPKER, R., HOLMBERG, S., ...

In order to reduce the delay times from onset of symptoms to arrival in hospital, and increase the use of ambulance in patients with suspected acute myocardial infarction (AMI), a media campaign was...

CORE ELECTRON SPECTROSCOPY OF SURFACE LAYERS ON LIQUID SUBSTRATES (1987)

Holmberg, S., Moberg, R., Bohman, O., Siegbahn, H.

Adsorbed layers of octanol and bromooctanol on top of formamide, are studied using core electron spectroscopy. In particular it is noted that the binding energy shift of the Br 3p line when going...

CORE ELECTRON SPECTROSCOPY OF SURFACE LAYERS ON LIQUID SUBSTRATES (1987)

Holmberg, S., Moberg, R., Bohman, O., Siegbahn, H.

Adsorbed layers of octanol and bromooctanol on top of formamide, are studied using core electron spectroscopy. In particular it is noted that the binding energy shift of the Br 3p line when going...

CORE ELECTRON SPECTROSCOPY OF SURFACE LAYERS ON LIQUID SUBSTRATES (1987)

Holmberg, S., Moberg, R., Bohman, O., Siegbahn, H.

Adsorbed layers of octanol and bromooctanol on top of formamide, are studied using core electron spectroscopy. In particular it is noted that the binding energy shift of the Br 3p line when going...

Mortality and morbidity in suspected acute myocardial infarction in relation to ambulance transport (1987)

Herlitz, J., Hjalmarson, Å, Holmberg, S., Richterova, A., Wennerblom, B.

In 681 patients admitted to the coronary care unit (CCU) at Sahlgrenska hospital between 1 May 1983 and 31 May 1984, due to suspected acute myocardial infarction (MI), the hospital mortality and...

Cardiomyopathy in phaeochromocytoma: Report of a case with a 16-year follow-up after surgery and review of the literature (1985)

STENSTRÖM, G., HOLMBERG, S.

A 39-year-old woman had suffered from congestive heart failure of unknown cause for 3.5 years before a phaeochromocytoma was diagnosed. After pretreatment with phenoxybenzamine, the tumour was...

Resuscitation of patients in cardiac arrest outside hospital. Comparison of two different organizations of mobile coronary care in one community (1984)

WENNERBLOM, B., EKSTRÖM, L., HOLMBERG, S.

We have compared the effectiveness of two different mobile coronary care systems with regard to mortality from cardiac arrest (CA) outside hospital in Gothenburg, Sweden.In period 1, the mobile...

Death outside hospital with special reference to heart disease (1984)

WENNERBLOM, B., HOLMBERG, S.

For one year (1 September 1975-31 August 1976) an analysis was made of all deaths occurring outside hospital in the Gothenburg area (population 480000). The total number of deaths was 1309. It was...

Effects of felodipine on systemic and coronary haemodynamics in patients with angina pectoris (1984)

EMANUELSSON, H., HJALMARSON, Å., HOLMBERG, S., WAAGSTEIN, F.

In order to study the systemic and coronary haemodynamic effects of felodipine, a new dihydropyridine derivative, 10 patients with coronary artery disease were studied during cardiac catheterizalion....

The effect of a mobile coronary care unit on mortality in patients with acute myocardial infarction or cardiac arrest outside hospital (1982)

WENNERBLOM, B., HOLMBERG, S., WEDEL, H.

Patients requesting an ambulance for symptoms suggestive of acute myocardial infarction (AMI) were randomized by the ambulance controllers to the hospital-based mobile coronary care unit (MCCU) or to...

Antiarrhythmic efficacy and side- effects of lidocaine given in the prehospital phase of acute myocardial infarction (1982)

WENNERBLOM, B., HOLMBERG, S., RYDÉN, L., WEDEL, H.

One hundred and fifty-one patients with suspected AMI received 300 mg lidocaine i.m. or a placebo, double-blind and at random before being transported to hospital by a mobile coronary care unit....

Pre-hospital identification of patients with acute myocardial infarction: A pilot study for a mobile coronary care unit (1982)

WENNERBLOM, B., HOLMBERG, S.

The aim of this study was to determine what proportion of patients with acute myocardial infarction (AMI) could be identified over the telephone by the staff of a Swedish ambulance center (AC). Over...

Comparative amino acid sequence analysis of the C6 zinc cluster family of transcriptional regulators.

Schjerling, P, Holmberg, S

The C6 zinc cluster family of fungal regulatory proteins shares as DNA-binding motif the C6 zinc cluster, also known as the Zn(II)2Cys6 binuclear cluster. This family includes transcriptional...

The ILV5 gene of Saccharomyces cerevisiae is highly expressed.

Petersen, J G, Holmberg, S

The nucleotide sequence of the yeast ILV5 gene, which codes for the branched-chain amino acid biosynthesis enzyme acetohydroxyacid reductoisomerase, has been determined. The ILV5 coding region is...

A REB1-binding site is required for GCN4-independent ILV1 basal level transcription and can be functionally replaced by an ABF1-binding site.

Remacle, J E, Holmberg, S

The ILV1 gene of Saccharomyces cerevisiae encodes the first committed step in isoleucine biosynthesis and is regulated by general control of amino acid biosynthesis. Deletion analysis of the ILV1...

A regulatory element in the CHA1 promoter which confers inducibility by serine and threonine on Saccharomyces cerevisiae genes.

Bornaes, C, Ignjatovic, M W, Schjerling, P, Kielland-Brandt, M C, Holmberg, S

CHA1 of Saccharomyces cerevisiae is the gene for the catabolic L-serine (L-threonine) dehydratase, which is responsible for biodegradation of serine and threonine. We have previously shown that...

Nucleosome structure of the yeast CHA1 promoter: analysis of activation-dependent chromatin remodeling of an RNA-polymerase-II-transcribed gene in TBP and RNA pol II mutants defective in vivo in response to acidic activators.

Moreira, J M, Holmberg, S

The Saccharomyces cerevisiae CHA1 gene encodes the catabolic L-serine (L-threonine) dehydratase. We have previously shown that the transcriptional activator protein Cha4p mediates serine/threonine...

Transcriptional repression of the yeast CHA1 gene requires the chromatin-remodeling complex RSC.

Moreira, J M, Holmberg, S

In eukaryotes, DNA is packaged into chromatin, a compact structure that must be disrupted when genes are transcribed by RNA polymerase II. For transcription to take place, chromatin is remodeled via...

HIV and hepatitis B infection and risk behavior in young gay and bisexual men.

Seage, G R, Mayer, K H, Lenderking, W R, Wold, C, Gross, M, Goldstein, R, ...

OBJECTIVES: To estimate the prevalence of and identify risk factors for human immunodeficiency virus type 1 (HIV-1) and hepatitis B virus (HBV) infections and unprotected anal intercourse among young...

Molecular Genetics of Serine and Threonine Catabolism in Saccharomyces Cerevisiae

Petersen, JGL., Kielland-Brandt, M. C., Nilsson-Tillgren, T., Bornaes, C., Holmberg, S.

The catabolic L-serine (L-threonine) deaminase of Saccharomyces cerevisiae allows the yeast to grow on media with L-serine or L-threonine as sole nitrogen source. A mutant, cha1 (catabolism of...

Serine and Threonine Catabolism in Saccharomyces Cerevisiae: The Cha1 Polypeptide Is Homologous with Other Serine and Threonine Dehydratases

Bornaes, C., Petersen, JGL., Holmberg, S.

The catabolic L-serine (L-threonine) dehydratase of Saccharomyces cerevisiae allows the yeast to grow on media with L-serine or L-threonine as sole nitrogen source. Previously we have cloned the CHA1...

Cha4p of Saccharomyces Cerevisiae Activates Transcription via Serine/Threonine Response Elements

Holmberg, S., Schjerling, P.

The CHA1 gene of Saccharomyces cerevisiae encodes the catabolic L-serine (L-threonine) deaminase responsible for the utilization of serine/threonine as nitrogen sources. Previously, we identified two...

Comparative amino acid sequence analysis of the C6 zinc cluster family of transcriptional regulators.

Schjerling, P, Holmberg, S

The C6 zinc cluster family of fungal regulatory proteins shares as DNA-binding motif the C6 zinc cluster, also known as the Zn(II)2Cys6 binuclear cluster. This family includes transcriptional...

The ILV5 gene of Saccharomyces cerevisiae is highly expressed.

Petersen, J G, Holmberg, S

The nucleotide sequence of the yeast ILV5 gene, which codes for the branched-chain amino acid biosynthesis enzyme acetohydroxyacid reductoisomerase, has been determined. The ILV5 coding region is...

A REB1-binding site is required for GCN4-independent ILV1 basal level transcription and can be functionally replaced by an ABF1-binding site.

Remacle, J E, Holmberg, S

The ILV1 gene of Saccharomyces cerevisiae encodes the first committed step in isoleucine biosynthesis and is regulated by general control of amino acid biosynthesis. Deletion analysis of the ILV1...

A regulatory element in the CHA1 promoter which confers inducibility by serine and threonine on Saccharomyces cerevisiae genes.

Bornaes, C, Ignjatovic, M W, Schjerling, P, Kielland-Brandt, M C, Holmberg, S

CHA1 of Saccharomyces cerevisiae is the gene for the catabolic L-serine (L-threonine) dehydratase, which is responsible for biodegradation of serine and threonine. We have previously shown that...

Nucleosome structure of the yeast CHA1 promoter: analysis of activation-dependent chromatin remodeling of an RNA-polymerase-II-transcribed gene in TBP and RNA pol II mutants defective in vivo in response to acidic activators.

Moreira, J M, Holmberg, S

The Saccharomyces cerevisiae CHA1 gene encodes the catabolic L-serine (L-threonine) dehydratase. We have previously shown that the transcriptional activator protein Cha4p mediates serine/threonine...

Transcriptional repression of the yeast CHA1 gene requires the chromatin-remodeling complex RSC.

Moreira, J M, Holmberg, S

In eukaryotes, DNA is packaged into chromatin, a compact structure that must be disrupted when genes are transcribed by RNA polymerase II. For transcription to take place, chromatin is remodeled via...

Molecular Genetics of Serine and Threonine Catabolism in Saccharomyces Cerevisiae

Petersen, JGL., Kielland-Brandt, M. C., Nilsson-Tillgren, T., Bornaes, C., Holmberg, S.

The catabolic L-serine (L-threonine) deaminase of Saccharomyces cerevisiae allows the yeast to grow on media with L-serine or L-threonine as sole nitrogen source. A mutant, cha1 (catabolism of...

Serine and Threonine Catabolism in Saccharomyces Cerevisiae: The Cha1 Polypeptide Is Homologous with Other Serine and Threonine Dehydratases

Bornaes, C., Petersen, JGL., Holmberg, S.

The catabolic L-serine (L-threonine) dehydratase of Saccharomyces cerevisiae allows the yeast to grow on media with L-serine or L-threonine as sole nitrogen source. Previously we have cloned the CHA1...

Cha4p of Saccharomyces Cerevisiae Activates Transcription via Serine/Threonine Response Elements

Holmberg, S., Schjerling, P.

The CHA1 gene of Saccharomyces cerevisiae encodes the catabolic L-serine (L-threonine) deaminase responsible for the utilization of serine/threonine as nitrogen sources. Previously, we identified two...

HIV and hepatitis B infection and risk behavior in young gay and bisexual men.

Seage, G R, Mayer, K H, Lenderking, W R, Wold, C, Gross, M, Goldstein, R, ...

OBJECTIVES: To estimate the prevalence of and identify risk factors for human immunodeficiency virus type 1 (HIV-1) and hepatitis B virus (HBV) infections and unprotected anal intercourse among young...

A multicenter study of bacterial vaginosis in women with or at risk for human immunodeficiency virus infection.

Warren, D, Klein, R S, Sobel, J, Kieke, B, Brown, W, Schuman, P, ...

BACKGROUND: Bacterial vaginosis is a common gynecologic infection that has been associated with a variety of gynecologic and obstetric complications, including pelvic inflammatory disease,...

Effect of metoprolol on chest pain in acute myocardial infarction.

Herlitz, J, Hjalmarson, A, Holmberg, S, Pennert, K, Swedberg, K, Vedin, A, ...

A total of 1395 patients aged 40 to 74 years were included in a double blind trial with the beta 1 selective blocker metoprolol in suspected acute myocardial infarction. Metoprolol was given...

Development of congestive heart failure after treatment with metoprolol in acute myocardial infarction.

Herlitz, J, Hjalmarson, A, Holmberg, S, Swedberg, K, Vedin, A, Waagstein, F, ...

In a double blind study of metoprolol in the treatment of suspected acute myocardial infarction 698 patients (study group) received metoprolol and 697 a placebo (control group). Metoprolol was given...

Pacemaker dependence in patients with bifascicular block during acute anterior myocardial infarction.

Edhag, O, Bergfeldt, L, Edvardsson, N, Holmberg, S, Rosenqvist, M, Vallin, H

Eleven patients with bifascicular block complicating anteroseptal acute myocardial infarction were studied to determine the effect of prophylactic permanent pacing; eight of them also had transient...

Out-of-hospital resuscitation in East Sussex: 1981 to 1989.

Lewis, S J, Holmberg, S, Quinn, E, Baker, K, Grainger, R, Vincent, R, ...

OBJECTIVE--To assess the impact of extended training in advanced life support on the outcome of resuscitation. DESIGN--Analysis of the successful resuscitations from 1981 to 1989. SETTING--Brighton...

Effect of bystander initiated cardiopulmonary resuscitation on ventricular fibrillation and survival after witnessed cardiac arrest outside hospital.

Herlitz, J, Ekström, L, Wennerblom, B, Axelsson, A, Bång, A, Holmberg, S

OBJECTIVE--To describe the proportion of patients who were discharged from hospital after witnessed cardiac arrest outside hospital in relation to whether a bystander initiated cardiopulmonary...

Randomised trial of elective stenting after successful percutaneous transluminal coronary angioplasty of occluded coronary arteries

Hancock, J, Thomas, M, Holmberg, S, Wainwright, R, Jewitt, D

Background—The value of angioplasty in occluded coronary arteries is limited by a restenosis/reocclusion rate of 50-70%. In patients with subtotal occlusion, stent implantation has been shown to...

Characteristics and outcome among patients having out of hospital cardiac arrest at home compared with elsewhere

Herlitz, J, Eek, M, Holmberg, M, Engdahl, J, Holmberg, S

Objective: To describe the characteristics and outcome of patients who have a cardiac arrest at home compared with elsewhere out of hospital.

Can we define patients with no chance of survival after out-of-hospital cardiac arrest?

Herlitz, J, Engdahl, J, Svensson, L, Young, M, Ängquist, K-A, Holmberg, S

Objective: To evaluate whether subgroups of patients with no chance of survival can be defined among patients with out-of-hospital cardiac arrest.