Scientific Commons: S. Horie

La méthode de bronchoscopie que nous utilisons à notre Institut est démontrée dans le film que nous avons présenté. Les caractéristiques particulièrement intéressantes de cette méthode sont...

The role of fiberscope in the diagnosis of cancer of terminal bronchus : (A Cuffed Bronchoscopy and Applied Various Examinations in the Diagnosis of Cancer of the Terminal Bronchus) (1974)

HANZAWA, S., HORIE, S., KATSUKI, H.

Role of protein kinase C and transcription factor AP-1 in the acid-induced increase in Na/H antiporter activity.

Horie, S, Moe, O, Yamaji, Y, Cano, A, Miller, R T, Alpern, R J

Chronic incubation of cultured renal tubular epithelial cells in acid medium causes an increase in Na/H antiporter activity that persists after removal from acid, is dependent on protein synthesis,...

Preincubation in acid medium increases Na/H antiporter activity in cultured renal proximal tubule cells.

Horie, S, Moe, O, Tejedor, A, Alpern, R J

Chronic acidosis in vivo leads to an increase in proximal tubule Na/H antiporter activity that persists when the transporter is studied out of the acidotic environment. It is presently not clear...

The Schizosaccharomyces pombe mei4+ Gene Encodes a Meiosis-Specific Transcription Factor Containing a forkhead DNA-Binding Domain

Horie, S., Watanabe, Y., Tanaka, K., Nishiwaki, S., Fujioka, H., Abe, H., ...

The mei4+ gene of the fission yeast Schizosaccharomyces pombe was cloned by functional complementation. The mei4 disruptant failed to complete meiosis-I but could proliferate normally. mei4+ was...

Differential regulation of Na/H antiporter by acid in renal epithelial cells and fibroblasts.

Moe, O W, Miller, R T, Horie, S, Cano, A, Preisig, P A, Alpern, R J

Increased Na/H antiporter activity has been demonstrated after in vivo chronic metabolic acidosis as well as in vitro acid preincubation of cultured rabbit renal tubule cells. To study the underlying...

Long-term activation of protein kinase c causes chronic Na/H antiporter stimulation in cultured proximal tubule cells.

Horie, S, Moe, O, Miller, R T, Alpern, R J

To examine the role of protein kinase C as a chronic regulator of proximal tubule Na/H antiporter activity, the effect of phorbol 12-myristate 13-acetate (PMA) on the Na/H antiporter was studied in...

Induction of stress proteins in cultured myogenic cells. Molecular signals for the activation of heat shock transcription factor during ischemia.

Benjamin, I J, Horie, S, Greenberg, M L, Alpern, R J, Williams, R S

Expression of major stress proteins is induced rapidly in ischemic tissues, a response that may protect cells from ischemic injury. We have shown previously that transcriptional induction of...

Retinoic acid stimulates expression of thrombomodulin, a cell surface anticoagulant glycoprotein, on human endothelial cells. Differences between up-regulation of thrombomodulin by retinoic acid and cyclic AMP.

Horie, S, Kizaki, K, Ishii, H, Kazama, M

Thrombomodulin (TM) is a surface protein on endothelial cells, and represents one of the most valuable regulatory factors in the anticoagulant system. In this paper, we demonstrate that retinoic acid...

Participation of peroxisomes in lipid biosynthesis in the harderian gland of guinea pig.

Horie, S, Suga, T

Peroxisomal enzyme activities in the guinea-pig harderian gland, which has a unique lipid composition, were studied. Activities of catalase, acyl-CoA oxidase and the cyanide-insensitive acyl-CoA...

Enhancement of thrombin-thrombomodulin-catalysed protein C activation by phosphatidylethanolamine containing unsaturated fatty acids: possible physiological significance of phosphatidylethanolamine in anticoagulant activity of thrombomodulin.

Horie, S, Ishii, H, Hara, H, Kazama, M

The effects of phospholipid vesicles and their fatty acid compositions on the acceleration of Protein C activation by thrombin-thrombomodulin was studied in vitro. Four main phospholipid fractions...

Oxidized low-density lipoprotein impairs the anti-coagulant function of tissue-factor-pathway inhibitor through oxidative modification by its high association and accelerated degradation in cultured human endothelial cells.

Horie, S, Hiraishi, S, Hirata, Y, Kazama, M, Matsuda, J

We have examined whether oxidized low-density lipoprotein (ox-LDL) affects the function of tissue-factor-pathway inhibitor (TFPI), an anti-coagulant regulator in the extrinsic pathway of coagulation,...

Role of protein kinase C and transcription factor AP-1 in the acid-induced increase in Na/H antiporter activity.

Horie, S, Moe, O, Yamaji, Y, Cano, A, Miller, R T, Alpern, R J

Chronic incubation of cultured renal tubular epithelial cells in acid medium causes an increase in Na/H antiporter activity that persists after removal from acid, is dependent on protein synthesis,...

Preincubation in acid medium increases Na/H antiporter activity in cultured renal proximal tubule cells.

Horie, S, Moe, O, Tejedor, A, Alpern, R J

Chronic acidosis in vivo leads to an increase in proximal tubule Na/H antiporter activity that persists when the transporter is studied out of the acidotic environment. It is presently not clear...

The Schizosaccharomyces pombe mei4+ Gene Encodes a Meiosis-Specific Transcription Factor Containing a forkhead DNA-Binding Domain

Horie, S., Watanabe, Y., Tanaka, K., Nishiwaki, S., Fujioka, H., Abe, H., ...

The mei4+ gene of the fission yeast Schizosaccharomyces pombe was cloned by functional complementation. The mei4 disruptant failed to complete meiosis-I but could proliferate normally. mei4+ was...

Differential regulation of Na/H antiporter by acid in renal epithelial cells and fibroblasts.

Moe, O W, Miller, R T, Horie, S, Cano, A, Preisig, P A, Alpern, R J

Increased Na/H antiporter activity has been demonstrated after in vivo chronic metabolic acidosis as well as in vitro acid preincubation of cultured rabbit renal tubule cells. To study the underlying...

Long-term activation of protein kinase c causes chronic Na/H antiporter stimulation in cultured proximal tubule cells.

Horie, S, Moe, O, Miller, R T, Alpern, R J

To examine the role of protein kinase C as a chronic regulator of proximal tubule Na/H antiporter activity, the effect of phorbol 12-myristate 13-acetate (PMA) on the Na/H antiporter was studied in...

Induction of stress proteins in cultured myogenic cells. Molecular signals for the activation of heat shock transcription factor during ischemia.

Benjamin, I J, Horie, S, Greenberg, M L, Alpern, R J, Williams, R S

Expression of major stress proteins is induced rapidly in ischemic tissues, a response that may protect cells from ischemic injury. We have shown previously that transcriptional induction of...

Retinoic acid stimulates expression of thrombomodulin, a cell surface anticoagulant glycoprotein, on human endothelial cells. Differences between up-regulation of thrombomodulin by retinoic acid and cyclic AMP.

Horie, S, Kizaki, K, Ishii, H, Kazama, M

Thrombomodulin (TM) is a surface protein on endothelial cells, and represents one of the most valuable regulatory factors in the anticoagulant system. In this paper, we demonstrate that retinoic acid...

Participation of peroxisomes in lipid biosynthesis in the harderian gland of guinea pig.

Horie, S, Suga, T

Peroxisomal enzyme activities in the guinea-pig harderian gland, which has a unique lipid composition, were studied. Activities of catalase, acyl-CoA oxidase and the cyanide-insensitive acyl-CoA...

Enhancement of thrombin-thrombomodulin-catalysed protein C activation by phosphatidylethanolamine containing unsaturated fatty acids: possible physiological significance of phosphatidylethanolamine in anticoagulant activity of thrombomodulin.

Horie, S, Ishii, H, Hara, H, Kazama, M

The effects of phospholipid vesicles and their fatty acid compositions on the acceleration of Protein C activation by thrombin-thrombomodulin was studied in vitro. Four main phospholipid fractions...

Oxidized low-density lipoprotein impairs the anti-coagulant function of tissue-factor-pathway inhibitor through oxidative modification by its high association and accelerated degradation in cultured human endothelial cells.

Horie, S, Hiraishi, S, Hirata, Y, Kazama, M, Matsuda, J

We have examined whether oxidized low-density lipoprotein (ox-LDL) affects the function of tissue-factor-pathway inhibitor (TFPI), an anti-coagulant regulator in the extrinsic pathway of coagulation,...

Analysis of recombinant human tumour necrosis factor-alpha-induced CD4 expression on human eosinophils.

Hossain, M, Okubo, Y, Horie, S, Sekiguchi, M

We examined the hypothesis that one of the pro-inflammatory cytokines, tumour necrosis factor-alpha (TNF-alpha), could induce expression of the adhesion molecule CD4 on human eosinophils. We further...

Intercellular adhesion molecule-1 on eosinophils is involved in eosinophil protein X release induced by cytokines.

Horie, S, Okubo, Y, Hossain, M, Momose, T, Suzuki, J, Isobe, M, ...

Recent evidence suggests that adhesion molecules play important roles in eosinophil functions such as degranulation and superoxide anion production. CD11b/CD18 (Mac-1) and CD49d/CD29 (VLA-4) are...

Differential effects of Na+, K(+)-ATPase inhibition by ouabain on acid secretory responses to histamine and bethanechol in the mouse isolated stomach.

Horie, S., Yano, S., Watanabe, K.

1. The effect of Na+,K(+)-ATPase inhibition by ouabain on gastric acid secretion was studied in the mouse isolated whole stomach preparation. 2. Ouabain caused a transient enhancement of...

S. Horie

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