6Li/7Li estimates for metal-poor stars (2009)
Perez, A. E. Garcia, Aoki, W., Inoue, S., Ryan, S. G., Suzuki, T. K., Chiba, M.
The presence of the lithium-6 isotope in some metal-poor stars is a matter of surprise because of the high values observed. Non-standard models of Big Bang nucleosynthesis and pre-Galactic cosmic ray...
JEM-EUSO Science Objectives (2009)
Medina-Tanco, Gustavo, Asano, K., Cline, D., Ebisuzaki, T., Inoue, S., Lipari, P., ...
JEM-EUSO, on board of the Japanese Exploration Module of the International Space Station, is being proposed as the first space observatory devoted to UHECR. Its privileged position at 430 km above...
MAGIC Gamma-Ray Observation of the Perseus Galaxy Cluster (2009)
Pfrommer, C., Pinzke, A., Ensslin, T. A., Inoue, S., Ghisellini, G.
The Perseus galaxy cluster was observed by the MAGIC Cherenkov telescope for a total effective time of 24.4 hours during November and December 2008. The resulting upper limits on the gamma-ray...
Hadron-gamma discrimination from an orbital UHECR observatory (2009)
Supanitsky, A. D., Medina-Tanco, G., Asano, K., Cline, D., Ebisuzaki, T., Inoue, S., ...
The identification of very high energy photons is of great importance for the understanding of the origin of extreme energy cosmic rays (EECR). Several can be the sources of high energy photons at...
Development of neutrino initiated cascades at mid and high altitudes in the atmosphere (2009)
Supanitsky, A. D., Medina-Tanco, G., Asano, K., Cline, D., Ebisuzaki, T., Inoue, S., ...
Neutrinos are a very promising messenger at tens of EeV and above. They can be produced by several channels, namely as by products of hadronic interactions at the sources, as the main products of the...
Multi-Wavelength Observation of Electron Acceleration in the 2006 December 13 Flare (2009)
Minoshima, T., Imada, S., Morimoto, T., Kawate, T., Koshiishi, H., Kubo, M., ...
We present a multi-wavelength observation of a solar flare occurring on 2006 December 13 with Hinode, RHESSI, and the Nobeyama Radio Observatory, to study the electron acceleration site and...
Lithium abundances of extremely metal-poor turnoff stars. (2009)
Aoki, W., Barklem, P.S., Beers, T.C., Christlieb, N., Inoue, S., Garcia Perez, A.E., ...
Original article can be found at: http://www.iop.org/EJ/journal/apj Copyright American Astronomical Society. DOI: 10.1088/0004-637X/698/2/1803 [Full text of this article is not available in the UHRA]
6Li/7Li estimates for metal-poor stars. (2009)
Garcia Perez, A.E., Aoki, W., Inoue, S., Ryan, S.G., Suzuki, T.K., Chiba, M.
Original article can be found at: http://www.aanda.org/ Copyright The European Southern Observatory (ESO) DOI: 10.1051/0004-6361/200912289
W. Fang, A. Van Genderen, R. Ishihara, R. Vikas, N. Karaki, Y. Hiroschima, ...
This paper describes a newly developed procedure to apply automated circuit design to single-grain Si TFTs fabricated through the µ-Czochralski (Grain Filter) Process. A standard cell library, which...
Effects of pneumococcal vaccine in patients with chronic respiratory disease (2008)
Yuji Watanuki, N. Miyazawa, M. Kudo, S. Inoue, H. Goto, H. Takahashi, ...
In developed countries, it is very difficult to demonstrate the effectiveness of pneumococcal vaccines because the incidence of pneumococcal pneumonia is very low. Vaccination against pneumococci...
FT-ICR Reaction Experiments and Molecular Dynamics Simulations of Precursor Clusters for (2007)
S. Maruyama, M. Kohno, T. Mukae, Y. Shibuta, S. Inoue
Generation mechanism of single walled carbon nanotubes is investigated through experimental and molecular dynamics simulation studies of interaction of metal atom and carbon clusters. Fourier...
Iwata, M., Inoue, S., Kawaguchi, M., Nakamura, M., Konishi, N., Furuya, H.
Background It has been reported that delta-opioid (DOP) receptor agonists may be neuroprotective in the central nervous system. However, the DOP agonist [d-Ala2, d-Leu5]enkephalin (DADLE) does not...
Growth Mechanism and Selective Synthesis of SWNTs (2007)
Inoue, S., Nakajima, T., Nomura, K., Kikuchi, Y.
Ever since the landmark discovery of single-walled carbon nanotubes (SWNTs) in 1993, they have been considered as ideal materials for any kind of application based on their outstanding properties...
Inoue, S., Richards, T., Howard, A., Thompson, A.
The Wagyu breed of beef cattle is renowned for its ability to deposithigh levels of intramuscular fat resulting in highly marbled beef thatmeets consumer demands in some niche export markets. We...
Malau-Aduli, AEO, Inoue, S, Richards, T, Howard, A, Thompson, A
The Wagyu breed of beef cattle is renowned for its ability to deposit high levels of intramuscular fat resulting in highly marbled beef that meets consumer demands in some niche export markets. We...
Gel phase formation at resin-modified glass-ionomer/tooth interfaces (2007)
Yoshida, Y, Inoue, S, Fukuda, R, Nakayama, Y, ...
Ionic bonding between polyalkenoic acid and hydroxyapatite may explain the excellent bonding retention of glass-ionomers in clinical trials. We have here investigated the extent to which the...
Restoring cervical lesions with flexible composites (2007)
Kanumilli, P, Yoshida, Y, Inoue, S, ...
Objectives. Flexure at the tooth cervix has been suggested to dislodge cervical restorations more rapidly The objective of this randomized controlled clinical trial was to test the hypothesis that a...
Ultrahigh energy cosmic rays as heavy nuclei from cluster accretion shocks (2007)
Inoue, S., Sigl, G., Miniati, F., Armengaud, E.
Large-scale accretion shocks around massive clusters of galaxies, generically expected in the cold dark matter scenario of cosmological structure formation, are shown to be plausible sources of the...
Malau-Aduli, AEO, Inoue, S, Richards, T, Howard, A, Thompson, A
The Wagyu breed of beef cattle is renowned for its ability to deposit high levels of intramuscular fat resulting in highly marbled beef that meets consumer demands in some niche export markets. We...
Malau-Aduli, AEO, Inoue, S, Richards, T, Howard, A, Thompson, A
The Wagyu breed of beef cattle is renowned for its ability to deposit high levels of intramuscular fat resulting in highly marbled beef that meets consumer demands in some niche export markets. We...
Development of a self-etch adhesive for resin-modified glass ionomers (2006)
Yoshida, Y, Inoue, S, ...
The favorable self-adhesiveness of resin-modified glass ionomers (RMGIs) might be even further improved if the time-consuming and technically sensitive etch-and-rinse pre-treatment step with...
Bimala Devi Devkota, H. Omura, T. Kubota, P. Paudel, S. Inoue
A general trend of decreasing soil loss rates with increasing vegetation cover fraction is widely accepted and is a critical parameter of empirical and process based soil erosion prediction model....
Growth Mechanism and Selective Synthesis of SWNTs (2006)
Inoue, S., Nakajima, T., Nomura, K., Kikuchi, Y.
Ever since the landmark discovery of single-walled carbon nanotubes (SWNTs) in 1993, they have been considered as ideal materials for any kind of application based on their outstanding properties...
Growth Mechanism and Selective Synthesis of SWNTs (2006)
Inoue, S., Nakajima, T., Nomura, K., Kikuchi, Y.
Ever since the landmark discovery of single-walled carbon nanotubes (SWNTs) in 1993, they have been considered as ideal materials for any kind of application based on their outstanding properties...
Local delivery of doxorubicin for malignant glioma by a biodegradable PLGA polymer sheet (2006)
Manome, Y, Kobayashi, T, Mori, M, Suzuki, R, Funamizu, N, Akiyama, N, ...
Bimala Devi Devkota, H. Omura, T. Kubota, P. Paudel, S. Inoue
A general trend of decreasing soil loss rates with increasing vegetation cover fraction is widely accepted and is a critical parameter of empirical and process based soil erosion prediction model....
Kawaraguchi, Y., Otomo, T., Ota, C., Uchida, N., Taniguchi, A., Inoue, S.
Background. It has been reported that ropivacaine produces vasoconstriction in contrast to vasodilation produced by bupivacaine. It is possible that additives to ropivacaine can provide further...
Inoue, S, Fujimoto, Y, Furuya, H
No Abstract Available A case that underwent bilateral video-assisted thoracoscopic surgical (VATS) biopsy combined with pneumonectomy is presented. The patient developed hypoxia during the...
Fatigue behavior of packable composites (2005)
Braem, M J A, Inoue, S, Takeuchi, M
The aim of this study was to investigate the flexural fatigue behavior of 11 packable composites. Of each material 30 rectangular samples (1.2 x 5 x 35 mm) for flexural fatigue test were prepared....
武田, 淳, Oguri, S., Hanado, O., Takeda, Jun, Furuya, M., Ohno, K., ...
Photoinduced magnetic phase transition in an organic radical 1,3,5-trithia-2,4,6-triazapentalenyl (TTTA) crystal has been studied by microscopic IR measurements. Both photoexcitations of the...
Micro-rotary fatigue of tooth-biomaterial interfaces (2005)
Braem, M., Yoshida, Y., Inoue, S., Suzuki, K., ...
The bonding effectiveness of restorative materials to tooth tissue is typically measured statically. Clinically tooth/composite bonds are however subjected to cyclic sub-critical loads. Therefore, in...
Monomer-solvent phase separation in one-step self-etch adhesives (2005)
Yoshida, Y, ...
One-step adhesives bond less effectively to enamel/dentin than do their multi-step versions. To investigate whether this might be due to phase separation between adhesive ingredients, we...
DFT makes the morphologies of anatase-TiO2 nanoparticles visible to IR spectroscopy (2005)
Dzwigaj, S., Arrouvel, C., Breysse, M., Geantet, C., Inoue, S., Toulhoat, H., ...
We use a multitechnique approach to reveal how the nature and concn. of surface acid-basic OH groups present on anatase-TiO2 nanocrystallites depend on their morphologies. Coupling recent d....
Rana, V., Ishihara, R., Hiroshima, Y., Abe, D., Inoue, S., Shimoda, T., ...
Matsuura, M, Okazaki, K, Nishio, A, Nakase, H, Tamaki, H, Uchida, K, ...
Koizumi, A, Yoshinaga, T, Harada, K, Inoue, K, Morikawa, A, Muroi, J, ...
Wada, Y, Koizumi, A, Yoshinaga, T, Harada, K, Inoue, K, Morikawa, A, ...
Effect of Si addition on In2O3 crystallization in soda-boro-alumino silicate glass (2005)
Chong, I, Ishii, F, Todoroki, S, Suehara, S, Konishi, T, Inoue, S, ...
Polycrystalline silicon ion sensitive field effect transistors (2005)
Yan, F., Estrela, Pedro, Mo, Y., Migliorato, P., Maeda, H., Inoue, S., ...
We report the operation of polycrystalline silicon ion sensitive field effect transistors. These devices can be fabricated on inexpensive disposable substrates such as glass or plastics and are,...
Yoshitani, K., Kawaguchi, M., Iwata, M., Sasaoka, N., Inoue, S., Kurumatani, N., ...
Background. A severe reduction in haemoglobin concentration can lead to a decrease in jugular venous bulb oxygen saturation (Sjo2). However, recent evidences suggests that cerebral oxygen saturation...
A low upper-limit on the lithium isotope ratio in HD140283 (2004)
Aoki, W., Inoue, S., Kawanomoto, S., Ryan, S.G., Smith, I.M., Suzuki, T.K., ...
Mutations in SLC6A19, encoding B0AT1, cause Hartnup disorder (2004)
Kleta, R., Romeo, E., Ristic, Z., Ohura, T., Stuart, C., Arcos-Burgos, M., ...
Hartnup disorder, an autosomal recessive defect named after an English family described in 1956 (ref. 1), results from impaired transport of neutral amino acids across epithelial cells in renal...
Mutations in SLC6A19, encoding B0AT1, cause Hartnup disorder (2004)
Kleta, R., Romeo, E., Ristic, Z., Ohura, T., Stuart, C., Arcos-Burgos, M., ...
Hartnup disorder, an autosomal recessive defect named after an English family described in 1956 (ref. 1), results from impaired transport of neutral amino acids across epithelial cells in renal...
Comparative study on adhesive performance of functional monomers (2004)
Nagakane, K, Fukuda, R, Nakayama, Y, Okazaki, M, Shintani, H, ...
Mild self-etch adhesives demineralize dentin only partially, leaving hydroxyapatite around collagen within a submicron hybrid layer. We hypothesized that this residual hydroxyapatite may serve as a...
Single-grain Si TFTs with ECR-PECVD gate SiO/sub 2/ (2004)
Ishihara, R., Hiroshima, Y., Abe, D., Van Dijk, B.D., Van Der Wilt, P.C., Higashi, S., ...
Rana, V., Ishihara, R., Hiroshima, Y., Abe, D., Inoue, S., Shimoda, T., ...
A low upper-limit on the lithium isotope ratio in HD140283 (2004)
Aoki, W., Inoue, S., Kawanomoto, S., Ryan, S. G., Smith, I. M., Suzuki, T. K., ...
Smallest carbon nanotube is 3 A in diameter (2004)
Zhao, X., Liu, Y., Inoue, S., Suzuki, T., Jones, G. J., Ando, Y.
This version is available at the following Publisher URL: http://prl.aps.org
Yoshitani, K., Kawaguchi, M., Iwata, M., Sasaoka, N., Inoue, S., Kurumatani, N., ...
Background. A severe reduction in haemoglobin concentration can lead to a decrease in jugular venous bulb oxygen saturation (SjO2). However, recent evidences suggests that cerebral oxygen saturation...
Inoue, S., Nishimine, N., Kitaguchi, K., Furuya, H., Taniguchi, S.
Background. Poor positioning of an endobronchial double lumen tube (DLT) could affect oxygenation during one lung ventilation (OLV). We set out to relate DLT position to hypoxaemia and DLT...
Left double lumen tube malposition (2004)
Fortier, G., Coté, D., Soucy, J., Lelièvre, R., Bussières, J., Inoue, S., ...
Yoshitani, K., Kawaguchi, M., Iwata, M., Sasaoka, N., Inoue, S., Kurumatani, N., ...
Background. A severe reduction in haemoglobin concentration can lead to a decrease in jugular venous bulb oxygen saturation (SjO2). However, recent evidences suggests that cerebral oxygen saturation...
Chemical bonding potential of adhesive materials to hydroxyapatite (2003)
Yoshida, Y, Shirai, K, Inoue, S, Shintani, H, ...
In vivo long-term durability of adhesives bonded to monkey dentin (2003)
Koshiro, K, Inoue, S, Tanaka, T, Koase, K, Hujita, M, Hashimoto, M, ...
Bonding efficacy of polyalkenoic acids to hydroxyapatite, enamel and dentin (2003)
Yoshida, Y, Nakayama, Y, Okazaki, M, Inoue, S, Sano, H, ...
Previously, we introduced a methodology to determine the chemical bonding potential of polyalkenoic acids to mineralized tissues through quantification of the degree of ionic bond formation between...
Four-year water degradation of total-etch adhesives bonded to dentin (2003)
Yoshida, Y, Inoue, S, Vargas, M, Suzuki, K, ...
Resin-dentin bonds degrade over time. The objective of this study was to evaluate the influence of variables like hybridization effectiveness and diffusion/elution of interface components on...
New generation of titanium dioxide support for hydrodesulfurization (2003)
Dzwigaj, S., Louis, C., Breysse, M., Cattenot, M., Belliere, V., Geantet, C., ...
Iwata, T., Inoue, S., Kawaguchi, M., Takahashi, M., Sakamoto, T., Kitaguchi, K., ...
Background. Because the time available for cooling and rewarming during deliberate mild hypothermia is limited, studies of the rate of the cooling and rewarming are useful. The decrease in core...
Improved filler-matrix coupling in resin composites (2002)
Nakayama, Y, Itoh, M, Okazaki, M, Shintani, H, ...
Ineffective silane coupling between filler and matrix within dental composites is prone to accelerated in vivo degradation. In this study, we examined to what degree a procedure involving chemical...
Micro-tensile bond strength of 4 total-etch adhesives to dentin after 4-year water storage (2002)
Yoshida, Y, Inoue, S, Vargas, M, ...
Adhesion/decalcification mechanisms of acid interactions with human hard tissues (2002)
Yoshida, Y, Inoue, S, Nomura, Y, ...
In order to study adhesion/decalcification mechanisms of acid interactions with human hard tissues such as bones and teeth, the chemical interaction of five carboxylic acids (acetic, citric, lactic,...
Kakimoto, M., Kawaguchi, M., Sakamoto, T., Inoue, S., Takahashi, M., Furuya, H.
Background. A number of authors have reported that anaesthetics suppress myogenic motor evoked potentials (MEPs). However, the influence of hypothermia on these effects is unknown. Therefore we...
Dynamic elastic modulus of 'packable' composites (2001)
Inoue, S, Braem, M J, Takeuchi, M, ...
OBJECTIVE: A new type of so-called 'packable', 'condensable' or 'mouldable' composite has been developed and aims at replacing amalgam for posterior restorations. The purpose of the present...
Five-year Monitorings of TeV Blazars with ASCA and RXTE (2001)
Kataoka, J., Takahashi, T., Takahara, F., Edwards, P. G., Hayashida, K., Inoue, S., ...
We study the temporal/spectral variability of two extragalactic TeV sources, Mrk 421 and Mrk 501, based on 5-year observations with the ASCA and RXTE satellites. We found that the peak of the...
Sakamoto, T., Kawaguchi, M., Inoue, S., Furuya, H.
The effect of nitrous oxide on myogenic motor evoked potentials (MEPs) after multipulse stimulation is controversial. We investigated the effects of propofol in this paradigm. MEPs were elicited...
Inoue, S., Kawaguchi, M., Sakamoto, T., Iwata, T., Kawaraguchi, Y., Furuya, H., ...
We investigated the effects of i.v. amrinone on intraoperative changes of core temperature during deliberate mild hypothermia for neurosurgery. The patients in a control group (n=10) did not...
Microscopy investigations. Techniques, results, limitations (2000)
Vargas, M, Inoue, S, Yoshida, Y, Perdigão, J, ...
This paper critically reviews current microscopy techniques that are used to image resin-dentin interfaces and more in particular to investigate the process of hybridization and resin-tag formation....
Rapid Synchrotron Flares from BL Lacertae Detected by ASCA and RXTE (2000)
Tanihata, C., Takahashi, T., Kataoka, J., Madejski, G. M., Inoue, S., Kubo, H., ...
We report the variable X-ray emission from BL Lacertae detected in the ASCA ToO observation conducted during the EGRET and RXTE pointings, coincident with the 1997 July outburst. The source showed a...
Chemical Reaction of Metal-Carbon Binary Cluster Anions by FT-ICR Mass Spectrometer (2000)
S. Maruyama, M. Kohno, S. Inoue
clusters contaminated with a hydrogen atom was very curious. One hydrogen atom made odd-numbered clusters less reactive and evennumbered clusters more reactive. These experimental results were...
Micro-tensile bond strength of an experimental resin-modified glass-ionomer adhesive (2000)
Inoue, S, Abe, Y, Yoshida, Y, ...
Goosecoid suppresses cell growth and enhances neuronal differentiation of PC12 cells. (2000)
Sawada, K., Konishi, Y., Tominaga, M., Watanabe, Y., Hirano, J., Inoue, S., ...
Journal of Cell Science, 113(2000) S.2705-13
Variability Pattern and the Spectral Evolution of the BL Lacertae Object PKS 2155-304 (1999)
Kataoka, J., Takahashi, T., Makino, F., Inoue, S., Madejski, G. M., Tashiro, M., ...
The TeV blazar PKS 2155-304 was monitored with the X-ray satellite ASCA in 1994 May, as part of a multiwavelength campaign from the radio to X-ray bands. At the beginning of the two-day continuous...
FT-ICR Study of Chemical Reaction of Silicon Clusters (1999)
S. Maruyama, M. Kohno, S. Inoue
e ICR cell by the selective RF excitation called "SWIFT" (Stored Waveform Inverse Fourier Transform) technique. It was especially crucial for reaction of ethylene that has the same mass of...
Kataoka, J., Mattox, J. R., Quinn, J., Kubo, H., Makino, F., Takahashi, T., ...
We present the results of a multiwavelength campaign for Mrk 501 performed in March 1996 with ASCA, EGRET, Whipple, and optical telescopes. In the X-ray band, a spectral break was observed around 2...
ASCA Observations of Blazars and Multiband Analysis (1998)
Kubo, H., Takahashi, T., Madejski, G., Tashiro, M., Makino, F., Inoue, S., ...
We present data for 18 blazars observed with ASCA, half of which were also observed contemporaneously with EGRET as parts of multi-wavelength campaigns. The observations show a clear difference in...
Koch's triangle sized up: anatomical landmarks in perspective of catheter ablation procedures (1998)
Inoue, S, Tanaka, H, Fujita, E, Kubo, M, Hirakata, H, Fukushima, Y, ...
Emission from Isolated Black Holes and MACHOs Accreting from the Interstellar Medium (1997)
Fujita, Y., Inoue, S., Nakamura, T., Manmoto, T., Nakamura, K. E.
Adopting the advection dominated accretion flow (ADAF) model, we have re-examined the radiation emitted by isolated stellar-mass black holes accreting from the interstellar medium of our Galaxy. Two...
EFFECT OF EXTRADURAL COMPLIANCE AND RESISTANCE ON SPREAD OF EXTRADURAL ANALGESIA (1990)
HIRABAYASHI, Y., SHIMIZU, R., MATSUDA, I., INOUE, S.
We have studied the effect of extradural compliance and extradural resistance on the spread of extradural analgesia. In 111 patients aged 21–75 yr, compliance and resistance of the extradural space...
GLASS-FORMING TENDENCY OF Pb-CONTAINING MULTICOMPONENT CHLORIDE AND BROMIDE MELTS (1982)
Yamane, M., Inoue, S., Nakamura, A.
The glass-forming tendency of Pb-containing multi-component chloride and bromide melts has been investigated. The experiment was extended from binary eutectic compositions containing PbCl2 to ternary...
GLASS-FORMING TENDENCY OF Pb-CONTAINING MULTICOMPONENT CHLORIDE AND BROMIDE MELTS (1982)
Yamane, M., Inoue, S., Nakamura, A.
The glass-forming tendency of Pb-containing multi-component chloride and bromide melts has been investigated. The experiment was extended from binary eutectic compositions containing PbCl2 to ternary...
GLASS-FORMING TENDENCY OF Pb-CONTAINING MULTICOMPONENT CHLORIDE AND BROMIDE MELTS (1982)
Yamane, M., Inoue, S., Nakamura, A.
The glass-forming tendency of Pb-containing multi-component chloride and bromide melts has been investigated. The experiment was extended from binary eutectic compositions containing PbCl2 to ternary...
Ziak, M, Qu, B, Zuo, X, Zuber, C, Kanamori, A, Kitajima, K, ...
In tissues of higher organisms homopolymers of alpha2,8-linked N-acetylneuraminic acid can be found as a posttranslational modification on selected proteins. We report here the discovery of...
Genomic binding-site cloning reveals an estrogen-responsive gene that encodes a RING finger protein.
Inoue, S, Orimo, A, Hosoi, T, Kondo, S, Toyoshima, H, Kondo, T, ...
Estrogen receptor (ER)-binding fragments were isolated from human genomic DNA by using a recombinant ER protein. Using one of these fragments as a probe, we have identified an estrogen-responsive...
Ogawa, S, Inoue, S, Watanabe, T, Orimo, A, Hosoi, T, Ouchi, Y, ...
We have identified and characterized a novel human estrogen receptor (ER) beta isoform, ERbetacx, which is truncated at the C-terminal region but has an extra 26 amino acids due to alternative...
Inoue, S, Itagaki, S, Amano, F
Listeria monocytogenes is a facultative intracellular pathogen and survives within phagocytic cells by escaping from phagosomes into the cytoplasm. It has been reported that, in vivo, L....
Sugai, M, Fujiwara, T, Akiyama, T, Ohara, M, Komatsuzawa, H, Inoue, S, ...
A novel staphylolytic enzyme, ALE-1, acting on Staphylococcus aureus, was purified from a Staphylococcus capitis EPK1 culture supernatant. The optimal pH range for staphylolytic activity was 7 to 9....
In vitro antibacterial properties of AT-2266, a new pyridonecarboxylic acid.
Nakamura, S, Minami, A, Katae, H, Inoue, S, Yamagishi, J, Takase, Y, ...
AT-2266, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3 -carboxylic acid, is a new pyridonecarboxylic acid derivative with broad and potent antibacterial activity. It...
Inhibitory effects of polyethers on human immunodeficiency virus replication.
Nakamura, M, Kunimoto, S, Takahashi, Y, Naganawa, H, Sakaue, M, Inoue, S, ...
We examined the inhibitory activities of 10 polyether antibiotics on human immunodeficiency virus (HIV) type 1. These compounds caused concentration-dependent inhibition of HIV replication in primary...
New nalidixic acid resistance mutations related to deoxyribonucleic acid gyrase activity.
Yamagishi, J, Furutani, Y, Inoue, S, Ohue, T, Nakamura, S, Shimizu, M
In Escherichia coli K-12 mutants which had a new nalidixic acid resistance mutation at about 82 min on the chromosome map, cell growth was resistant to or hypersusceptible to nalidixic acid, oxolinic...
Sophorolipids from Torulopsis bombicola: possible relation to alkane uptake.
Torulopsis bombicola produces extracellular sophorolipids when it is grown on water-insoluble alkanes. Sophorolipids and related model compounds, which were not themselves used for growth, were found...
Weisenberg, R C, Allen, R D, Inoue, S
Microtubule proteins isolated from calf brain will undergo gelation-contraction in the presence of ATP. We have now examined this process by video-enhanced contrast microscopy. After ATP addition to...
Successful liver allografts in mice by combination with allogeneic bone marrow transplantation.
Nakamura, T, Good, R A, Yasumizu, R, Inoue, S, Oo, M M, Hamashima, Y, ...
Successful liver allografts were established by combination with allogeneic bone marrow transplantation. When liver tissue of BALB/c (H-2d) or C57BL/6J (H-2b) mice was minced and grafted under the...
Isolation of estrogen receptor-binding sites in human genomic DNA.
Inoue, S, Kondo, S, Hashimoto, M, Kondo, T, Muramatsu, M
Total genomic DNA digested by restriction enzymes was mixed with the DNA-binding domain of the estrogen receptor (ER-DBD) that was expressed in Escherichia coli and the fragments that bound to it...
Rationale for bone marrow transplantation in the treatment of autoimmune diseases.
Ikehara, S, Good, R A, Nakamura, T, Sekita, K, Inoue, S, Oo, M M, ...
Transplantation of normal bone marrow from C3H/HeN nu/nu (H-2k) mice into young MRL/MP-lpr/lpr (MRL/l; H-2k) mice (less than 1.5 mo) prevented the development of autoimmune diseases and...
Normal distribution of collagen IV in renal basement membranes in Epstein's syndrome.
Naito, I, Nomura, S, Inoue, S, Kagawa, M, Kawai, S, Gunshin, Y, ...
BACKGROUND: Epstein's syndrome is defined as a subtype of Alport's syndrome, and is distinguished from the other subtypes by accompanying macrothrombocytopenia. Mutations in collagen IV genes are...
Matsuse, T, Namba, Y, Ikeda, K, Inoue, S, Hosoi, T, Ouchi, Y, ...
To investigate whether brain tissue is infected latently by adenovirus via a monocyte/microglia-mediated entry mechanism, brain tissue resected at necropsy from seven senile subjects (five with...
Matsuse, T, Matsui, H, Shu, C Y, Nagase, T, Wakabayashi, T, Mori, S, ...
AIMS--To investigate adenovirus pulmonary infections in bone marrow transplant (BMT) recipients. METHODS--Formalin fixed, paraffin wax embedded lung tissue was examined from 13 necropsy cases after...
S100 beta is a target protein of neurocalcin delta, an abundant isoform in glial cells.
Okazaki, K, Obata, N H, Inoue, S, Hidaka, H
To clarify the function of neurocalcin delta, an isoform found abundantly in glial cells, we attempted to find its target proteins by using neurocalcin delta-affinity chromatography and the...
Chemical modification and inactivation of phospholipases A2 by a manoalide analogue.
Fujii, S, Tahara, Y, Toyomoto, M, Hada, S, Nishimura, H, Inoue, S, ...
Chemical modification and inactivation of bovine pancreatic, porcine pancreatic, Naja naja atra and Pseudechis australis phospholipases A2 (PLA2s), belonging to Group I, and of Trimeresurus...
Ohkura, N, Okuhara, H, Inoue, S, Ikeda, K, Hayashi, K
Three distinct types of phospholipase A2 (PLA2) inhibitory proteins (PLIalpha, PLIbeta, and PLIgamma) were isolated from the blood plasma of the Chinese mamushi, Agkistrodon blomhoffii siniticus....
Okumura, K, Masui, K, Inoue, S, Ikeda, K, Hayashi, K
The serum of a non-venomous striated snake, Elaphe quadrivirgata, was found to contain phospholipase A2 (PLA2) inhibitory proteins (PLIs). One of these inhibitors was purified by Sephadex G-200 gel...
Impaired reductive regeneration of ascorbic acid in the Goto-Kakizaki diabetic rat.
Kashiba, M, Oka, J, Ichikawa, R, Kageyama, A, Inayama, T, Kageyama, H, ...
Ascorbic acid (AA) is a naturally occurring major antioxidant that is essential for the scavenging of toxic free radicals in both plasma and tissues. AA levels in plasma and tissues have been...
Nawa, M., Takasaki, T., Ito, M., Inoue, S., Morita, K., Kurane, I.
We determined the usefulness of an immunoglobulin A (IgA) antibody-capture enzyme-linked immunosorbent assay for serodiagnosis of dengue virus infections. The results indicate that the presence of...
Tuzi, S, Yamaguchi, S, Tanio, M, Konishi, H, Inoue, S, Naito, A, ...
The high-affinity cation-binding sites of bacteriorhodopsin (bR) were examined by solid-state 13C NMR of samples labeled with [3-13C]Ala and [1-13C]Val. We found that the 13C NMR spectra of two kinds...
Tanio, M, Inoue, S, Yokota, K, Seki, T, Tuzi, S, Needleman, R, ...
We have recorded 13C cross-polarization-magic angle spinning and dipolar decoupled-magic angle spinning NMR spectra of [1-13C]Val-labeled wild-type bacteriorhodopsin (bR), and the V49A, V199A, T46V,...
Kaneko, T, Nakao, A, Inoue, S, Harada, A, Nonami, T, Itoh, S, ...
OBJECTIVE: The purpose of this study was to determine the value of intraportal endovascular ultrasonography (IPEUS) in the diagnosis of portal vein invasion by pancreatobiliary carcinoma. The authors...
One hundred hepatic resections. Indications and operative results.
Nagao, T, Inoue, S, Mizuta, T, Saito, H, Kawano, N, Morioka, Y
The indications and operative results of hepatic resections were investigated in 100 consecutive patients over the past 20 years. There were 61 hepatocellular carcinoma, 13 hepatolithiasis, and 26...
Postoperative recurrence of hepatocellular carcinoma.
Nagao, T, Inoue, S, Yoshimi, F, Sodeyama, M, Omori, Y, Mizuta, T, ...
Sixty-nine patients with hepatocellular carcinoma underwent curative hepatic resections as primary cases from 1981 to 1986. Seven patients died in the hospital after operation. The other 62 patients...
Unit responses in the medulla oblongata of rabbit to changes in local and cutaneous temperature.
1. In anaesthetized rabbits which were stereotaxically implanted with a thermode following decerebellation, thermal sensitivity of neurones in the medulla oblongata to local temperature changes was...
Hepatic resection for hepatocellular carcinoma. Clinical features and long-term prognosis.
Nagao, T, Inoue, S, Goto, S, Mizuta, T, Omori, Y, Kawano, N, ...
Ninety-eight hepatic resections for hepatocellular carcinoma were performed on 94 patients from 1963-1985. HBs antigen was positive in 17% of patients, preoperative serum alpha-fetoprotein was more...
Active oxygen species in DNA damage induced by carcinogenic metal compounds.
Kawanishi, S, Inoue, S, Yamamoto, K
Some carcinogenic metal compounds [chromate(VI), Fe(III) nitrilotriacetate, cobalt(II), and nickel(II)[ induced formation of various oxygen radical species in the presence of hydrogen peroxide. These...
Ziak, M, Qu, B, Zuo, X, Zuber, C, Kanamori, A, Kitajima, K, ...
In tissues of higher organisms homopolymers of alpha2,8-linked N-acetylneuraminic acid can be found as a posttranslational modification on selected proteins. We report here the discovery of...
Genomic binding-site cloning reveals an estrogen-responsive gene that encodes a RING finger protein.
Inoue, S, Orimo, A, Hosoi, T, Kondo, S, Toyoshima, H, Kondo, T, ...
Estrogen receptor (ER)-binding fragments were isolated from human genomic DNA by using a recombinant ER protein. Using one of these fragments as a probe, we have identified an estrogen-responsive...
Ogawa, S, Inoue, S, Watanabe, T, Orimo, A, Hosoi, T, Ouchi, Y, ...
We have identified and characterized a novel human estrogen receptor (ER) beta isoform, ERbetacx, which is truncated at the C-terminal region but has an extra 26 amino acids due to alternative...
Inoue, S, Itagaki, S, Amano, F
Listeria monocytogenes is a facultative intracellular pathogen and survives within phagocytic cells by escaping from phagosomes into the cytoplasm. It has been reported that, in vivo, L....
Sugai, M, Fujiwara, T, Akiyama, T, Ohara, M, Komatsuzawa, H, Inoue, S, ...
A novel staphylolytic enzyme, ALE-1, acting on Staphylococcus aureus, was purified from a Staphylococcus capitis EPK1 culture supernatant. The optimal pH range for staphylolytic activity was 7 to 9....
In vitro antibacterial properties of AT-2266, a new pyridonecarboxylic acid.
Nakamura, S, Minami, A, Katae, H, Inoue, S, Yamagishi, J, Takase, Y, ...
AT-2266, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3 -carboxylic acid, is a new pyridonecarboxylic acid derivative with broad and potent antibacterial activity. It...
Inhibitory effects of polyethers on human immunodeficiency virus replication.
Nakamura, M, Kunimoto, S, Takahashi, Y, Naganawa, H, Sakaue, M, Inoue, S, ...
We examined the inhibitory activities of 10 polyether antibiotics on human immunodeficiency virus (HIV) type 1. These compounds caused concentration-dependent inhibition of HIV replication in primary...
New nalidixic acid resistance mutations related to deoxyribonucleic acid gyrase activity.
Yamagishi, J, Furutani, Y, Inoue, S, Ohue, T, Nakamura, S, Shimizu, M
In Escherichia coli K-12 mutants which had a new nalidixic acid resistance mutation at about 82 min on the chromosome map, cell growth was resistant to or hypersusceptible to nalidixic acid, oxolinic...
Sophorolipids from Torulopsis bombicola: possible relation to alkane uptake.
Torulopsis bombicola produces extracellular sophorolipids when it is grown on water-insoluble alkanes. Sophorolipids and related model compounds, which were not themselves used for growth, were found...
Weisenberg, R C, Allen, R D, Inoue, S
Microtubule proteins isolated from calf brain will undergo gelation-contraction in the presence of ATP. We have now examined this process by video-enhanced contrast microscopy. After ATP addition to...
Successful liver allografts in mice by combination with allogeneic bone marrow transplantation.
Nakamura, T, Good, R A, Yasumizu, R, Inoue, S, Oo, M M, Hamashima, Y, ...
Successful liver allografts were established by combination with allogeneic bone marrow transplantation. When liver tissue of BALB/c (H-2d) or C57BL/6J (H-2b) mice was minced and grafted under the...
Isolation of estrogen receptor-binding sites in human genomic DNA.
Inoue, S, Kondo, S, Hashimoto, M, Kondo, T, Muramatsu, M
Total genomic DNA digested by restriction enzymes was mixed with the DNA-binding domain of the estrogen receptor (ER-DBD) that was expressed in Escherichia coli and the fragments that bound to it...
Rationale for bone marrow transplantation in the treatment of autoimmune diseases.
Ikehara, S, Good, R A, Nakamura, T, Sekita, K, Inoue, S, Oo, M M, ...
Transplantation of normal bone marrow from C3H/HeN nu/nu (H-2k) mice into young MRL/MP-lpr/lpr (MRL/l; H-2k) mice (less than 1.5 mo) prevented the development of autoimmune diseases and...
Normal distribution of collagen IV in renal basement membranes in Epstein's syndrome.
Naito, I, Nomura, S, Inoue, S, Kagawa, M, Kawai, S, Gunshin, Y, ...
BACKGROUND: Epstein's syndrome is defined as a subtype of Alport's syndrome, and is distinguished from the other subtypes by accompanying macrothrombocytopenia. Mutations in collagen IV genes are...
Matsuse, T, Namba, Y, Ikeda, K, Inoue, S, Hosoi, T, Ouchi, Y, ...
To investigate whether brain tissue is infected latently by adenovirus via a monocyte/microglia-mediated entry mechanism, brain tissue resected at necropsy from seven senile subjects (five with...
Matsuse, T, Matsui, H, Shu, C Y, Nagase, T, Wakabayashi, T, Mori, S, ...
AIMS--To investigate adenovirus pulmonary infections in bone marrow transplant (BMT) recipients. METHODS--Formalin fixed, paraffin wax embedded lung tissue was examined from 13 necropsy cases after...
S100 beta is a target protein of neurocalcin delta, an abundant isoform in glial cells.
Okazaki, K, Obata, N H, Inoue, S, Hidaka, H
To clarify the function of neurocalcin delta, an isoform found abundantly in glial cells, we attempted to find its target proteins by using neurocalcin delta-affinity chromatography and the...
Chemical modification and inactivation of phospholipases A2 by a manoalide analogue.
Fujii, S, Tahara, Y, Toyomoto, M, Hada, S, Nishimura, H, Inoue, S, ...
Chemical modification and inactivation of bovine pancreatic, porcine pancreatic, Naja naja atra and Pseudechis australis phospholipases A2 (PLA2s), belonging to Group I, and of Trimeresurus...
Ohkura, N, Okuhara, H, Inoue, S, Ikeda, K, Hayashi, K
Three distinct types of phospholipase A2 (PLA2) inhibitory proteins (PLIalpha, PLIbeta, and PLIgamma) were isolated from the blood plasma of the Chinese mamushi, Agkistrodon blomhoffii siniticus....
Okumura, K, Masui, K, Inoue, S, Ikeda, K, Hayashi, K
The serum of a non-venomous striated snake, Elaphe quadrivirgata, was found to contain phospholipase A2 (PLA2) inhibitory proteins (PLIs). One of these inhibitors was purified by Sephadex G-200 gel...
Impaired reductive regeneration of ascorbic acid in the Goto-Kakizaki diabetic rat.
Kashiba, M, Oka, J, Ichikawa, R, Kageyama, A, Inayama, T, Kageyama, H, ...
Ascorbic acid (AA) is a naturally occurring major antioxidant that is essential for the scavenging of toxic free radicals in both plasma and tissues. AA levels in plasma and tissues have been...
Kaneko, T, Nakao, A, Inoue, S, Harada, A, Nonami, T, Itoh, S, ...
OBJECTIVE: The purpose of this study was to determine the value of intraportal endovascular ultrasonography (IPEUS) in the diagnosis of portal vein invasion by pancreatobiliary carcinoma. The authors...
Nawa, M., Takasaki, T., Ito, M., Inoue, S., Morita, K., Kurane, I.
We determined the usefulness of an immunoglobulin A (IgA) antibody-capture enzyme-linked immunosorbent assay for serodiagnosis of dengue virus infections. The results indicate that the presence of...
One hundred hepatic resections. Indications and operative results.
Nagao, T, Inoue, S, Mizuta, T, Saito, H, Kawano, N, Morioka, Y
The indications and operative results of hepatic resections were investigated in 100 consecutive patients over the past 20 years. There were 61 hepatocellular carcinoma, 13 hepatolithiasis, and 26...
Tuzi, S, Yamaguchi, S, Tanio, M, Konishi, H, Inoue, S, Naito, A, ...
The high-affinity cation-binding sites of bacteriorhodopsin (bR) were examined by solid-state 13C NMR of samples labeled with [3-13C]Ala and [1-13C]Val. We found that the 13C NMR spectra of two kinds...
Tanio, M, Inoue, S, Yokota, K, Seki, T, Tuzi, S, Needleman, R, ...
We have recorded 13C cross-polarization-magic angle spinning and dipolar decoupled-magic angle spinning NMR spectra of [1-13C]Val-labeled wild-type bacteriorhodopsin (bR), and the V49A, V199A, T46V,...
Unit responses in the medulla oblongata of rabbit to changes in local and cutaneous temperature.
1. In anaesthetized rabbits which were stereotaxically implanted with a thermode following decerebellation, thermal sensitivity of neurones in the medulla oblongata to local temperature changes was...
Postoperative recurrence of hepatocellular carcinoma.
Nagao, T, Inoue, S, Yoshimi, F, Sodeyama, M, Omori, Y, Mizuta, T, ...
Sixty-nine patients with hepatocellular carcinoma underwent curative hepatic resections as primary cases from 1981 to 1986. Seven patients died in the hospital after operation. The other 62 patients...
Hepatic resection for hepatocellular carcinoma. Clinical features and long-term prognosis.
Nagao, T, Inoue, S, Goto, S, Mizuta, T, Omori, Y, Kawano, N, ...
Ninety-eight hepatic resections for hepatocellular carcinoma were performed on 94 patients from 1963-1985. HBs antigen was positive in 17% of patients, preoperative serum alpha-fetoprotein was more...
Active oxygen species in DNA damage induced by carcinogenic metal compounds.
Kawanishi, S, Inoue, S, Yamamoto, K
Some carcinogenic metal compounds [chromate(VI), Fe(III) nitrilotriacetate, cobalt(II), and nickel(II)[ induced formation of various oxygen radical species in the presence of hydrogen peroxide. These...
Matsuse, T., Ikegami, A., Ohga, E., Hosoi, T., Oka, T., Kida, K., ...
The expression of activin A, one of the transforming growth factor-beta supergene family, was studied in various pulmonary conditions associated with interstitial pulmonary fibrosis (3 cases with...
Augmentation effect of postprandial hyperinsulinaemia on growth of human hepatocellular carcinoma
Saito, K, Inoue, S, Saito, T, Kiso, S, Ito, N, Tamura, S, ...
Background: Cirrhotic patients with hepatocellular carcinoma (HCC) frequently have impaired glucose metabolism.
Efficacy of acycloguanosine against herpetic ulcers in rabbit cornea.
Shiota, H, Inoue, S, Yamane, S
The effect of a new antiherpetic compound of very low toxicity called acycloguanosine (Wellcome 248U) on herpetic ulcers in rabbit cornea was studied by the Corneal Epithelial Lesion Therapeutic...
JIN, G-B, NAKAYAMA, H, SHMYHLO, M, INOUE, S, KONDO, M, IKEZAWA, Z, ...
Two principal types of stress protein, heat shock proteins (hsps) and metallothionein (MT), are induced in cells responding to a variety of stresses. They play an important role in protecting cells...
SAITO, M, OISHI, K, INOUE, S, DIMAANO, E M, ALERA, M T P, ROBLES, A M P, ...
Severe thrombocytopenia and increased vascular permeability are two major characteristics of dengue haemorrhagic fever (DHF). To develop a better understanding of the roles of platelet-associated IgG...
Tanaka, Y., Inoue, S., Skoryna, S. C.
The inhibitory action of alginate on intestinal absorption of radioactive strontium was investigated in order to correlate the biological activity with the chemical composition. Alginate from...
Tonofilaments in normal human bronchial epithelium and in squamous cell carcinoma.
Tonofilaments in the cells of squamous cell carcinoma of human bronchial epithelium were observed and compared to those in normal bronchial epithelium in 2 patients. In the normal tissue, only small...
Okamura, T., Inoue, S., Toda, N.
1. Atrial natriuretic peptide (ANP) (10(-9) to 10(-8) M) produced a concentration-related relaxation in helical strips of dog cerebral arteries partially contracted with prostaglandin F2 alpha. The...
Moritoki, H., Hisayama, T., Takeuchi, S., Kondoh, W., Inoue, S., Kida, K.
1. We investigated the effect of SK&F96365, a putative inhibitor of receptor-operated Ca2+ entry, on the endothelium-dependent, NO-mediated relaxation and cyclic GMP formation induced by...
Hypothalamic obesity due to hydrocephalus caused by aqueductal stenosis.
Suzuki, N, Shinonaga, M, Hirata, K, Inoue, S, Kuwabara, T
A case is presented of 14 year old female with hypothalamic obesity due to hydrocephalus caused by aqueductal stenosis. Evidence of hypothalamic obesity included 1) acute hyperphagia and weight gain,...
Absenteeism among survivors of the atomic bombing of Hiroshima.
Meigs, J W, Blot, W J, Inoue, S, Meigs, C R
Atomic bomb survivors who worked at the Atomic Bomb Casualty Commission in Hiroshima during the years 1968-71 and held handbooks identifying them as survivors took significantly more days of both...
Miyamoto, T, Hagari, Y, Inoue, S, Watanabe, T, Yoshino, T
Background: Apocrine carcinoma is rare and often occurs in the axilla. This is the second apocrine carcinoma arising in bilateral axillae with associated apocrine hyperplasia to be reported.
EBAG9/RCAS1 in human breast carcinoma: a possible factor in endocrine–immune interactions
Suzuki, T, Inoue, S, Kawabata, W, Akahira, J, Moriya, T, Tsuchiya, F, ...
EBAG9 has been recently identified as an oestrogen responsive gene in MCF-7 human breast carcinoma cells. EBAG9 is identical to RCAS1, a cancer cell surface antigen possibly involved in immune...
Expression of EBAG9/RCAS1 is associated with advanced disease in human epithelial ovarian cancer
Akahira, J-i, Aoki, M, Suzuki, T, Moriya, T, Niikura, H, Ito, K, ...
Primary effusion lymphoma with skin involvement
Inoue, S, Miyamoto, T, Yoshino, T, Yamadori, I, Hagari, Y, Yamamoto, O
Primary effusion lymphoma (PEL) was once defined as a body cavity‐based lymphoma without identifiable contiguous tumour mass, but is now recognised as an independent clinicopathological entity. The...