Novel dithiolene complexes incorporating conjugated electroactive ligands (2008)
Skabara, P.J., Pozo-Gonzalo, C., Miazza, N.L., Laguna, M., Cerrada, E., Luquin, A., ...
A series of new metal (M) dithiolene complexes bearing terthiophene (3, 12, M = Ni; 4, M = Pd; 5, 6, M = Au) and 2,5-bis(para-methoxyphenyl)thiophene units (14, M = Ni; 15, 16, M = Au; 17, M = Pd)...
On the highly stereoselective addition of lithio-acetylides to alpha-hydroxy-ketones (2008)
Dunford, D., Guyader, M., Jones, S., Knight, D.W., Hursthouse, M.B., Coles, S.J.
Addition of 2 equiv of a lithio-acetylide to an unprotected α-hydroxy ketone is extremely stereoselective in examples where the two ketone substituents are relatively large.
Anion complexation via C–HX interactions using a palladacyclic receptor (2008)
Bedford, R.B., Betham, M., Butts, C.P., Coles, S.J., Hursthouse, M.B., Scully, P.N., ...
A novel organometallic receptor binds anions in solution and in the solid state, with complexes stabilised through a series of C–HX interactions, as evidenced by 1H NMR spectroscopy, X-ray...
The synthesis and structure of terpyridine-N-oxide complexes of copper(II) perchlorate (2008)
Amoroso, A.J., Burrows, M.W., Coles, S.J., Haigh, R., Farley, R.D., Hursthouse, M.B., ...
The co-ordination of a series of terpyridine-N-oxide ligands to the Cu(II) ion is reported. Addition of two equivalents of ligand results in the formation of the expected 2 : 1 six co-ordinate...
Anjos, T., Roberts-Bleming, S.J., Charlton, A., Robertson, N., Mount, A.R., Coles, S.J., ...
The synthesis, electrochemical and spectroscopic properties of the new thiophene-substituted metal dithiolene complexes [Ni(b-3ted)2] ( 3) and [NBu4][Ni(b-3ted)2] ([NBu4][ 3]) are described [b-3ted =...
Berry, D.J., Seaton, C.C., Clegg, W., Harrington, R.W., Coles, S.J., Horton, P.N., ...
Co-crystal screening is routinely undertaken using high-throughput solution growth. We report a low- to medium-throughput approach, encompassing both a melt and solution crystallization step as a...
Stable P-N bridged cyclophosphazenes with a spiro or ansa arrangement (2008)
Besli, S., Coles, S.J., Davies, D.B., Erkovan, A.O., Hursthouse, M.B., Kilic, A.
Deprotonation reactions of cyclophosphazenes containing secondary amino groups in the side chain lead to a doubly bridged tricyclophosphazene structure or to a...
Kinetics of iminium ion catalysis (2008)
Evans, G., Gibbs, T.J.K., Jenkins, R.L., Coles, S.J., Hursthouse, M.B., Platts, J.A., ...
To a stirred solution of cinnamaldehyde (118 mg, 1.42 mmol, 122 μl) in methanol (2ml), trifluoromethylpyrrolidine (198 mg, 1.42 mmol) was added and allowed to stir at ambient temperature for 2...
10,11-Dihydrodiindeno[1,2-b : 2 ',1 '-d]thiophene (2008)
Afonina, I., Coles, S.J., Hursthouse, M.B., Kanibolotsky, A., Skabara, P.J.
The title compound, C18H12S, comprises five fused rings forming an essentially planar molecule, with a total puckering amplitude (Q) of 0.032 Å and a maximum deviation from the mean plane of 0.014...
Noncovalent functional-group–arene interactions (2007)
Motherwell, W.B., Moïse, J., Nic, M., Coles, S.J., Horton, P.N., Hursthouse, M.B., ...
A catalytic asymmetric protocol for the enantioselective synthesis of 3(2H)-furanones (2007)
Marson, C.M., Edaan, E., Morrell, J.M., Coles, S.J., Hursthouse, M.B., Davies, D.T.
3(2H)-Furanones can be prepared by a catalytic asymmetric protocol from enynones, which, if electron-rich, require only one reagent and involve two reactions in a single operation—a domino process.
Besli, S., Coles, S.J., Davarci, D., Davies, D.B., Hursthouse, M.B., Kilic, A.
Reaction of cyclophosphazene, N3P3Cl6 (1), with the sodium derivative of the fluorinated diol, 2,2,3,3,4,4-hexafluoropentane-1,5-diol (2), in THF solution at room temperature afforded five isolated...
A catalytic asymmetric protocol for the enantioselective synthesis of 3(2H)-furanones (2007)
Marson, C.M., Edaan, E., Morrell, J.M., Coles, S.J., Hursthouse, M.B., Davies, D.T.
3(2H)-Furanones can be prepared by a catalytic asymmetric protocol from enynones, which, if electron-rich, require only one reagent and involve two reactions in a single operation—a domino process.
Mountford, A.J., Clegg, W., Coles, S.J., Harrington, R.W., Horton, P.N., Humphrey, S.M., ...
Treatment of the homoleptic titanium amides [Ti(NR2)4] (R=Me or Et) with the Brønsted acidic reagent H3NB(C6F5)3 results in the elimination of one molecule of amine and the formation of the...
Skabara, P.J., Kanibolotsky, A., Render, S., Berridge, R., Crouch, D.J., Bricklebank, N., ...
The synthesis of five new dihalogen/interhalogen charge transfer adducts featuring cyano and nitro functionalized 1,3-dithiole-2-thiones have been prepared and characterized by x-ray crystallography....
Smith, M.B., Dale, S.H., Coles, S.J., Gelbrich, T., Hursthouse, M.B., Light, M.E., ...
An isomeric series of seven, square-planar, neutral dichloropalladium(II) complexes cis-PdCl2{P,P-C6H3N(CH2PPh2)2(CO2H)(OH)} 2a–2g have been synthesised in high yields (70–99%) from PdCl2(cod)...
Bedford, R.B., Betham, M., Charmant, J.P.H., Haddow, M.F., Orpen, A.G., Pilarski, L.T., ...
range of palladacyclic, platinacyclic, and pincer-based catalysts have been tested for activity in 1,4-conjugate addition reactions. -Acidic palladacycles show excellent activity at room temperature...
Coe, B.J., Curati, N.R.M., Fitzgerald, E.C., Coles, S.J., Horton, P.N., Light, M.E., ...
We have prepared a family of six new bimetallic complexes containing electron-donating trans-{RuIICl(pdma)2}+ [pdma = 1,2-phenylenebis(dimethylarsine)] centers linked to...
Coles, S.J., Davies, D.B., Hursthouse, M.B., Kilic, A., Sahin, S., Shaw, R.A., ...
Derivatives of the tri-spirane pentaerythritoxy-cyclophosphazene compound 1 have been used to investigate the stereogenic properties of spiranes combined with either one or two conventional centres...
First examples of diazepanylidene carbenes and their late-transition-metal complexes (2007)
Lglesias, M., Beetstra, D.J., Stasch, A., Horton, P.N., Hursthouse, M.B., Coles, S.J., ...
The synthesis of the novel seven-membered N-heterocyclic carbene (NHC) 1,3-dicyclohexyl-1,3-diazepan-2-ylidene (3) and its 5,6-dioxolane derivative 4 is reported and their coordination chemistry with...
Noncovalent functional-group-arene interactions (2007)
Motherwell, W.B., Moise, J., Aliev, A.E., Nic, M., Coles, S.J., Horton, P.N., ...
Pang, H., Skabara, P.J., Crouch, D.J., Duffy, W., Heeney, M., McCulloch, I., ...
A series of conjugated triaryl compounds have been synthesized, consisting of thiophene or selenophene peripheral units and a central 1,3,4-thiadiazole (TDA) heterocycle. X-ray crystallographic...
Coles, S.J., Davies, D.B., Hacivelioglu, F., Hursthouse, M.B., Ibisoglu, H., Kilic, A., ...
A second, polymorphic, form of the previously reported compound 4,4,6,6-tetrachloro-2,2-(2,2-dimethylpropane-1,3-dioxy)cyclotriphosphazene, C5H10Cl4N3O2P3, is now reported. The molecular structures...
Coles, S.J., Davies, D.B., Hursthouse, M.B., Ibisoglu, H., Kilic, A., Shaw, R.A.
Reaction of the spermidine-bridged cyclophosphazene compound (N3P3Cl5)spd(N3P3Cl4) (spd = spermidine residue) with 2,4-dimethylthiophenol results in substitution of the P-Cl bond at the bridgehead...
Mountford, A.J., Lancaster, S.J., Coles, S.J.
The title ionic solid, [Ti(C2H6N)3(C2H7N)2][Ti(C18BF15N)(C18H2BF15N)Cl(C2H7N)2]·C7H8, (I), comprises a cation with three dimethylamide ligands in the equatorial plane and two dimethylamine ligands...
4-Nitrobenzyl 5-oxo-2-(2-oxopiperidin-1-yl)-tetrahydrofuran-2-carboxylate (2007)
Shanley, S.J., Schofield, C.J., Coles, S.J., Watkin, D.J., Fischer, D.S.
The title compound, C17H18N2O7, is a synthetic racemic analogue of lactivicin, a natural product antibiotic that targets penicillin-binding proteins. There are two almost identical molecules in the...
Skabara, P.J., Berridge, R., Bricklebank, N., Lath, H., Coles, S.J., Horton, P.N.
New halogen adducts of 1,3-dithiole-2-thione-4-carboxylic acid and dimethyl 1,3-dithiole-2-thione-4,5-dicarboxylate have been prepared and characterised by X-ray crystallographic studies. The adducts...
Crouch, D.J., Skabara, P.J., Lohr, J.E., McDouall, J.J.W., Heeney, M., McCulloch, I., ...
A series of thiophene oligomers bearing core phenylene and fluorinated phenylene units has been synthesized as potential semiconductor materials for organic field-effect transistors (OFETs)....
Spencer, H.J., Skabara, P.J., Giles, M., McCulloch, L., Coles, S.J., Hursthouse, M.B.
The structures of poly(3,4-ethylenedioxythiophene) (PEDOT) and poly(3,4-ethylenedithiathiophene) (PEDTT) vary only in the substituent chalcogen atoms, yet the electronic properties of the materials...
Bricklebank, N., Coles, S.J., Forder, S.D., Hursthouse, M.B., Poulton, A., Skabara, P.J.
The title compound, Fc(2)(Ph)PS.I-2, has been prepared and characterised in both the solid state and solution. Single crystal X-ray crystallography reveals that the adduct adopts a molecular...
Crouch, D.J., Skabara, P.J., Heeney, M., McCulloch, I., Coles, S.J., Hursthous, M.B.
Rigidification has been achieved in thiophene - tetrafluorophenylene architectures through strong S center dot center dot center dot F and H center dot center dot center dot F intramolecular...
Supramolecular polymers of 4,5-bis(bromomethyl)-1,3-dithiole-2-thione-dihalogen adducts (2004)
Lee, L., Crouch, D.J., Wright, S.P., Berridge, R., Skabara, P.J., Bricklebank, N., ...
The title compound has been reacted with I-2, IBr and ICl to afford the charge-transfer adducts 4.2I(2), 4.IBr and 4.ICl.I-2, respectively. The products have been characterised by Raman and IR...
Supramolecular polymers of 4,5-bis(bromomethyl)-1,3-dithiole-2-thione-dihalogen adducts (2004)
Lee, L., Crouch, D. J., Wright, S. P., Berridge, R., Skabara, P. J., Bricklebank, N., ...
The title compound has been reacted with I2, IBr and ICl to afford the charge-transfer adducts 4.2I2, 4.IBr and 4.ICl.½I2, respectively. The products have been characterised by Raman and IR...
Exceptional electron donating ability of an extended tetrathiafulvalene derivative (2004)
Khan, T., Skabara, P.J., Frere, P., Allain, M., Coles, S.J., Hursthouse, M.B.
We report the synthesis, crystal structures and redox chemistry of two new TTF derivatives bearing fused triaryl units. Both compounds show significant planarisation within conjugated regions,...
Skabara, P.J., Berridge, R., McInnes, E.J.L., West, D.P., Coles, S.J., Hursthouse, M.B., ...
The polymerisation of a fused 2,5-dibromothieno-TTF derivative has been achieved using Ni(COD)(2) as the catalyst. Whilst higher molecular weight fractions are sparingly soluble, lower weight samples...
Berridge, R., Serebryakov, I.M., Skabara, P.J., Orti, E., Viruela, R., Pou-Amerigo, R., ...
A new family of tetrathiafulvalenes has been prepared. The materials exhibit complex redox behaviour related to the electronic influence of the 1,4-dithiin moieties embedded within the framework of...
Structural and magnetic properties of a novel ferrocenyl-diiodine charge transfer complex (2003)
Allen, D.W., Berridge, R., Bricklebank, N., Forder, S.D., Palacio, F., Coles, S.J., ...
The reaction of 4-ferrocenyl-1,3-dithiole-2-thione with diiodine affords an unprecedented 'double' charge-transfer complex; the highly ordered ferrocenium units are held by a supramolecular...
Structural and magnetic properties of a novel ferrocenyl-diiodine (2003)
Allen, D. W., Berridge, R., Bricklebank, N., Forder, S. D., Palacio, F., Coles, S. J., ...
The reaction of 4-ferrocenyl-1,3-dithiole-2-thione with diiodine affords an unprecedented "double" charge-transfer complex; the highly ordered ferrocenium units are held by a supramolecular...
Spencer, H.J., Berridge, R., Crouch, D.J., Wright, S.P., Giles, M., McCulloch, I., ...
Three new, highly crystalline 2,5-dibromothiophene compounds polymerise on standing in the absence of solvent and catalyst; X-ray crystallography shows that the molecules are held in close proximity...
Khan, T., McDouall, J.J.W., McInnes, E.J.L., Skabara, P.J., Frere, P., Coles, S.J., ...
A series of symmetrical 1,3-dithiole-2-thiones and -ones have been prepared via double lithiation of vinylene trithiocarbonate followed by trapping of the dianions with aryl carbaldehydes. The...
Pozo-Gonzalo, C., Khan, T., McDouall, J.J.W., Skabara, P.J., Roberts, D.M., Light, M.E., ...
A new series of regioregular poly(terthiophenes), bearing bis( thioether) side groups, has been prepared by electrochemical oxidation. Cyclic voltammetry of the parent trimers reveals an increase in...
Pozo-Gonzalo, C., Berridge, R., Skabara, P.J., Cerrada, E., Laguna, M., Coles, S.J., ...
Bis(dithiolene) metal complexes incorporating fused terthiophene units have been prepared; the nickel analogue undergoes electropolymerisation to afford a low bandgap material with very broad...
Novel transition metal complexes based on covalently linked DMIT systems (2001)
Berridge, R., Bricklebank, N., Allen, D.W., Skabara, P.J., Malik, K.M.A., Coles, S.J., ...
The synthesis of a novel series of transition metal ligands and complexes is reported; the materials are related to the well-studied DMIT systems, allowing greater versatility in terms of structural...
Khan, T., Skabara, P.J., Coles, S.J., Hursthouse, M.B.
In the presence of perchloric acid, an unusual 1,4-aryl shift is observed for two electron-rich 4,5-bis[hydroxy(aryl)methyl]-1,3-dithiole-2-thiones; the X-ray crystal structure of compound 8 confirms...
Skabara, P.J., Bricklebank, N., Berridge, R., Long, S., Light, M.E., Coles, S.J., ...
The crystal structure of an iodine monobromide adduct of dimethyl 1,3-dithiole-2-thione-4,5-dicarboxylate reveals a layered polymeric network of donor and acceptor molecules linked primarily through...
Skabara, P.J., Berridge, R., Prescott, K., Goldenberg, L.M., Orti, E., Viruela, R., ...
The syntheses and electrochemistry of thieno[3',4'∶5,6][1,4]dithiino[2,3-b]quinoxaline (9), 2,3-bis(methylsulfanyl)[1,4]dithiino[2,3-b]quinoxaline (16) and...
Skabara, P.J., Serebryakov, I.M., Roberts, D.M., Perepichka, I.F., Coles, S.J., Hursthouse, M.B.
The syntheses of a series of 1,3-dithiole-2-thione derivatives (3-6), bearing fused terthiophene or bis(2-thienyl)-2,5-furan units, are reported. These novel heterocycles are readily polymerized...
Charge densities from high-resolution synchrotron X-ray diffraction experiments
Mallinson, P.R., Barr, G., Coles, S.J., Row, T.N.G., MacNicol, D.D., Teat, S.J., ...
The combination of intense X-ray sources, especially synchrotron radiation, with area-detector technology has accomplished an enormous advance in the experimental conditions available for...
Efthimiou, J, Mounsey, P J, Benson, D N, Madgwick, R, Coles, S J, Benson, M K
BACKGROUND: High calorie intakes, especially as carbohydrate, increase carbon dioxide production (VCO2) and may precipitate respiratory failure in patients with severe pulmonary disease. Energy...