S. J. Dolin

Effects of the calcium channel activator Bay K 8644 on general anaesthetic potency in mice.

Dolin, S. J., Halsey, M. J., Little, H. J.

1. The effects of the calcium channel activator, Bay K 8644, on the anaesthetic potencies of ethanol, argon and pentobarbitone were examined in mice. 2. Bay K 8644, at 1 mg kg-1 i.p., significantly...

Chronic dihydropyridine treatment can reverse the behavioural consequences of and prevent adaptations to, chronic ethanol treatment.

Whittington, M. A., Dolin, S. J., Patch, T. L., Siarey, R. J., Butterworth, A. R., Little, H. J.

1. Chronic treatment with the dihydropyridine calcium channel antagonist, nitrendipine, given concurrently with ethanol, prevented the ethanol withdrawal syndrome in mice, even though the chronic...

The effects of chronic treatment with the dihydropyridine, Bay K 8644, on hyperexcitability due to ethanol withdrawal, in vivo and in vitro.

Whittington, M. A., Butterworth, A. R., Dolin, S. J., Patch, T. L., Little, H. J.

1. The effects of chronic treatment with the dihydropyridine, Bay K 8644, were studied on the ethanol withdrawal syndrome, in vivo and in vitro. 2. Addition of racemic Bay K 8644 to the drinking...

Augmentation by calcium channel antagonists of general anaesthetic potency in mice.

Dolin, S. J., Little, H. J.

The effects of three kinds of calcium channel antagonists on the anaesthetic potencies of ethanol, pentobarbitone and argon were examined in mice. Ethanol and pentobarbitone anaesthetic potencies in...

Nitrendipine decreases benzodiazepine withdrawal seizures but not the development of benzodiazepine tolerance or withdrawal signs.

Dolin, S. J., Patch, T. L., Rabbani, M., Siarey, R. J., Bowhay, A. R., Little, H. J.

1. The effects of the calcium channel blocking agent, nitrendipine, were studied on seizures in mice produced during withdrawal from chronic benzodiazepine treatment and on the development of...